Dominique PV de Kleijn
Dominique PV de Kleijn
Experimental Vascular Surgery
Geverifieerd e-mailadres voor umcutrecht.nl
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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury
RC Lai, F Arslan, MM Lee, NSK Sze, A Choo, TS Chen, M Salto-Tellez, ...
Stem cell research 4 (3), 214-222, 2010
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse …
F Arslan, RC Lai, MB Smeets, L Akeroyd, A Choo, ENE Aguor, L Timmers, ...
Stem cell research 10 (3), 301-312, 2013
Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper
T Lener, M Gimona, L Aigner, V Börger, E Buzas, G Camussi, N Chaput, ...
Journal of extracellular vesicles 4 (1), 30087, 2015
Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium
L Timmers, SK Lim, F Arslan, JS Armstrong, IE Hoefer, PA Doevendans, ...
Stem cell research 1 (2), 129-137, 2008
Frameshift mutants of β amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients
FW Van Leeuwen, DPV de Kleijn, HH van den Hurk, A Neubauer, ...
Science 279 (5348), 242-247, 1998
Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury
L Timmers, JPS Henriques, DPV de Kleijn, JH DeVries, H Kemperman, ...
Journal of the American College of Cardiology 53 (6), 501-510, 2009
Composition of carotid atherosclerotic plaque is associated with cardiovascular outcome: a prognostic study
WE Hellings, W Peeters, FL Moll, SRD Piers, J van Setten, ...
Circulation 121 (17), 1941-1950, 2010
Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery
G Pasterkamp, AH Schoneveld, DJ Hijnen, DPV de Kleijn, H Teepen, ...
Atherosclerosis 150 (2), 245-253, 2000
Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction
L Timmers, SK Lim, IE Hoefer, F Arslan, RC Lai, AAM van Oorschot, ...
Stem cell research 6 (3), 206-214, 2011
Proteolytic potential of the MSC exosome proteome: implications for an exosome-mediated delivery of therapeutic proteasome
RC Lai, SS Tan, BJ Teh, SK Sze, F Arslan, DP De Kleijn, A Choo, SK Lim
International journal of proteomics 2012, 2012
Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
L Timmers, JPG Sluijter, JK van Keulen, IE Hoefer, MGJ Nederhoff, ...
Circulation research 102 (2), 257-264, 2008
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti–toll-like receptor-2 antibody
F Arslan, MB Smeets, LAJ O'Neill, B Keogh, P McGuirk, L Timmers, ...
Circulation 121 (1), 80-90, 2010
Innate immune signaling in cardiac ischemia
F Arslan, DP De Kleijn, G Pasterkamp
Nature Reviews Cardiology 8 (5), 292-300, 2011
In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded …
JI Rotmans, JMM Heyligers, HJM Verhagen, E Velema, MM Nagtegaal, ...
Circulation 112 (1), 12-18, 2005
In vivo evidence for a role of toll-like receptor 4 in the development of intimal lesions
A Vink, AH Schoneveld, JJ van der Meer, BJ van Middelaar, JPG Sluijter, ...
Circulation 106 (15), 1985-1990, 2002
Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs
TS Chen, F Arslan, Y Yin, SS Tan, RC Lai, ABH Choo, J Padmanabhan, ...
Journal of translational medicine 9 (1), 1-10, 2011
Defining mesenchymal stromal cell (MSC)-derived small extracellular vesicles for therapeutic applications
KW Witwer, BWM Van Balkom, S Bruno, A Choo, M Dominici, M Gimona, ...
Journal of extracellular vesicles 8 (1), 1609206, 2019
The innate immune response in reperfused myocardium
L Timmers, G Pasterkamp, VC de Hoog, F Arslan, Y Appelman, ...
Cardiovascular research 94 (2), 276-283, 2012
Elucidating the secretion proteome of human embryonic stem cell-derived mesenchymal stem cells
SK Sze, DPV de Kleijn, RC Lai, EKW Tan, H Zhao, KS Yeo, TY Low, ...
Molecular & Cellular Proteomics 6 (10), 1680-1689, 2007
TGF-β1 induces efficient differentiation of human cardiomyocyte progenitor cells into functional cardiomyocytes in vitro
MJ Goumans, TP de Boer, AM Smits, LW van Laake, P van Vliet, ...
Stem cell research 1 (2), 138-149, 2008
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