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Koen van de Wetering
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Multidrug resistance-associated proteins 3, 4, and 5
P Borst, C de Wolf, K van de Wetering
Pflügers Archiv-European Journal of Physiology 453, 661-673, 2007
3752007
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
S Rottenberg, AOH Nygren, M Pajic, FWB van Leeuwen, ...
Proceedings of the National Academy of Sciences 104 (29), 12117-12122, 2007
3672007
Collectins: players of the innate immune system
JK Van De Wetering, LMG Van Golde, JJ Batenburg
European Journal of Biochemistry 271 (7), 1229-1249, 2004
3252004
ABCC6–mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation—brief report
RS Jansen, S Duijst, S Mahakena, D Sommer, F Szeri, A Váradi, A Plomp, ...
Arteriosclerosis, thrombosis, and vascular biology 34 (9), 1985-1989, 2014
2862014
Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception
N Zelcer, K van de Wetering, M Hillebrand, E Sarton, A Kuil, PR Wielinga, ...
Proceedings of the National Academy of Sciences 102 (20), 7274-7279, 2005
2452005
ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release
RS Jansen, A Küçükosmanoğlu, M De Haas, S Sapthu, JA Otero, ...
Proceedings of the National Academy of Sciences 110 (50), 20206-20211, 2013
2382013
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
N Zelcer, K van de Wetering, R de Waart, GL Scheffer, HU Marschall, ...
Journal of hepatology 44 (4), 768-775, 2006
2082006
Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin
R Beedholm-Ebsen, K van de Wetering, T Hardlei, E Nexř, P Borst, ...
Blood, The Journal of the American Society of Hematology 115 (8), 1632-1639, 2010
1712010
Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol
K van de Wetering, A Burkon, W Feddema, A Bot, H de Jonge, V Somoza, ...
Molecular pharmacology 75 (4), 876-885, 2009
1612009
MRP2 and 3 in health and disease
P Borst, N Zelcer, K Van De Wetering
Cancer letters 234 (1), 51-61, 2006
1432006
Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides
K van de Wetering, N Zelcer, A Kuil, W Feddema, M Hillebrand, ...
Molecular pharmacology 72 (2), 387-394, 2007
1292007
An exercise-inducible metabolite that suppresses feeding and obesity
VL Li, Y He, K Contrepois, H Liu, JT Kim, AL Wiggenhorn, JT Tanzo, ...
Nature 606 (7915), 785-790, 2022
1192022
Functionally overlapping roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate in vivo
MLH Vlaming, Z Pala, A van Esch, E Wagenaar, DR de Waart, ...
Clinical Cancer Research 15 (9), 3084-3093, 2009
1172009
Oral administration of pyrophosphate inhibits connective tissue calcification
D Dedinszki, F Szeri, E Kozák, V Pomozi, N Tőkési, TR Mezei, K Merczel, ...
EMBO molecular medicine 9 (11), 1463-1470, 2017
1062017
Characteristics of surfactant protein A and D binding to lipoteichoic acid and peptidoglycan, 2 major cell wall components of gram-positive bacteria
J de Wetering, M Van Eijk, LMG Van Golde, T Hartung, JAG Van Strijp, ...
Journal of Infectious Diseases 184 (9), 1143, 2001
1052001
On the putative co-transport of drugs by multidrug resistance proteins
P Borst, N Zelcer, K Van de Wetering, B Poolman
FEBS letters 580 (4), 1085-1093, 2006
912006
Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo
MLH Vlaming, A van Esch, Z Pala, E Wagenaar, K van de Wetering, ...
Molecular cancer therapeutics 8 (12), 3350-3359, 2009
882009
Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?
P Borst, K van de Wetering, R Schlingemann
Cell Cycle 7 (11), 1575-1579, 2008
832008
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides
C De Wolf, R Jansen, H Yamaguchi, M De Haas, K Van De Wetering, ...
Molecular cancer therapeutics 7 (9), 3092-3102, 2008
802008
Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the In vivo Elimination of Methotrexate and its Main Toxic Metabolite 7-hydroxymethotrexate
MLH Vlaming, Z Pala, A van Esch, E Wagenaar, O van Tellingen, ...
Clinical Cancer Research 14 (24), 8152-8160, 2008
772008
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