| Network pharmacology: curing causal mechanisms instead of treating symptoms C Nogales, ZM Mamdouh, M List, C Kiel, AI Casas, HHHW Schmidt Trends in Pharmacological Sciences 43 (2), 136-150, 2022 | 346 | 2022 |
| European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 314 | 2017 |
| From single drug targets to synergistic network pharmacology in ischemic stroke AI Casas, AA Hassan, SJ Larsen, V Gomez-Rangel, M Elbatreek, ... Proceedings of the National Academy of Sciences 116 (14), 7129-7136, 2019 | 160 | 2019 |
| Reactive oxygen-related diseases: therapeutic targets and emerging clinical indications AI Casas, VTV Dao, A Daiber, GJ Maghzal, F Di Lisa, N Kaludercic, ... Antioxidants & redox signaling 23 (14), 1171-1185, 2015 | 148 | 2015 |
| NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage AI Casas, E Geuss, PWM Kleikers, S Mencl, AM Herrmann, I Buendia, ... Proceedings of the National Academy of Sciences 114 (46), 12315-12320, 2017 | 133 | 2017 |
| Agmatine, by improving neuroplasticity markers and inducing Nrf2, prevents corticosterone-induced depressive-like behavior in mice AE Freitas, J Egea, I Buendia, V Gómez-Rangel, E Parada, E Navarro, ... Molecular Neurobiology 53, 3030-3045, 2016 | 99 | 2016 |
| Pharmacology and clinical drug candidates in redox medicine VTV Dao, AI Casas, GJ Maghzal, T Seredenina, N Kaludercic, ... Antioxidants & redox signaling 23 (14), 1113-1129, 2015 | 87 | 2015 |
| On the clinical pharmacology of reactive oxygen species AI Casas, C Nogales, HAM Mucke, A Petraina, A Cuadrado, AI Rojo, ... Pharmacological reviews 72 (4), 801-828, 2020 | 85 | 2020 |
| Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke AI Casas, PWM Kleikers, E Geuss, F Langhauser, T Adler, DH Busch, ... The Journal of clinical investigation 129 (4), 1772-1778, 2019 | 72 | 2019 |
| Simultaneous determination of 8 neurotransmitters and their metabolite levels in rat brain using liquid chromatography in tandem with mass spectrometry: Application to the … A Wojnicz, JA Ortiz, AI Casas, AE Freitas, MG Lopez, A Ruiz-Nuno Clinica Chimica Acta 453, 174-181, 2016 | 71 | 2016 |
| Simultaneous determination of 8 neurotransmitters and their metabolite levels in rat brain using liquid chromatography in tandem with mass spectrometry: Application to the … A Wojnicz, JA Ortiz, AI Casas, AE Freitas, MG Lopez, A Ruiz-Nuno Clinica Chimica Acta 453, 174-181, 2016 | 69 | 2016 |
| Isoform-selective NADPH oxidase inhibitor panel for pharmacological target validation VTV Dao, MH Elbatreek, S Altenhöfer, AI Casas, MP Pachado, ... Free Radical Biology and Medicine 148, 60-69, 2020 | 67 | 2020 |
| A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection F Langhauser, AI Casas, VTV Dao, E Guney, J Menche, E Geuss, ... NPJ systems biology and applications 4 (1), 8, 2018 | 55 | 2018 |
| Early toll‐like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodent and human brain ischaemia models E Parada, AI Casas, A Palomino‐Antolin, V Gómez‐Rangel, ... British Journal of Pharmacology 176 (15), 2764-2779, 2019 | 52 | 2019 |
| Network medicine for disease module identification and drug repurposing with the NeDRex platform S Sadegh, J Skelton, E Anastasi, J Bernett, DB Blumenthal, G Galindez, ... Nature Communications 12 (1), 6848, 2021 | 51 | 2021 |
| Thromboinflammation in Brain Ischemia: Recent Updates and Future Perspectives SF De Meyer, F Langhauser, S Haupeltshofer, C Kleinschnitz, AI Casas Stroke 53 (5), 1487-1499, 2022 | 25 | 2022 |
| NOS knockout or inhibition but not disrupting PSD-95-NOS interaction protect against ischemic brain damage C Kleinschnitz, S Mencl, PWM Kleikers, MK Schuhmann, M G López, ... Journal of Cerebral Blood Flow & Metabolism 36 (9), 1508-1512, 2016 | 22 | 2016 |
| Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia A Palomino‐Antolin, P Narros‐Fernández, V Farré‐Alins, ... British Journal of Pharmacology 179 (7), 1395-1410, 2022 | 19 | 2022 |
| Clinical relevance of cyclic GMP modulators: A translational success story of network pharmacology JM Oettrich, VT Dao, J Frijhoff, PWM Kleikers, AI Casas, AJ Hobbs, ... Clinical Pharmacology & Therapeutics 99 (4), 360-362, 2016 | 18 | 2016 |
| Implication of type 4 NADPH oxidase (NOX4) in tauopathy E Luengo, P Trigo-Alonso, C Fernández-Mendívil, Á Nuñez, ... Redox Biology 49, 102210, 2022 | 17 | 2022 |
