Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman, ... Science 306 (5695), 457-461, 2004 | 4558 | 2004 |
A central role for JNK in obesity and insulin resistance J Hirosumi, G Tuncman, L Chang, CZ Görgün, KT Uysal, K Maeda, ... Nature 420 (6913), 333-336, 2002 | 4163 | 2002 |
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2 M Furuhashi, G Tuncman, CZ Görgün, L Makowski, G Atsumi, ... Nature 447 (7147), 959-965, 2007 | 857 | 2007 |
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis T Nakamura, M Furuhashi, P Li, H Cao, G Tuncman, N Sonenberg, ... Cell 140 (3), 338-348, 2010 | 589 | 2010 |
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance G Tuncman, J Hirosumi, G Solinas, L Chang, M Karin, GS Hotamisligil Proceedings of the National Academy of Sciences 103 (28), 10741-10746, 2006 | 450 | 2006 |
Adipocyte/macrophage fatty acid–binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice M Furuhashi, R Fucho, CZ Görgün, G Tuncman, H Cao, GS Hotamisligil The Journal of clinical investigation 118 (7), 2640-2650, 2008 | 386 | 2008 |
A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease G Tuncman, E Erbay, X Hom, I De Vivo, H Campos, EB Rimm, ... Proceedings of the National Academy of Sciences 103 (18), 6970-6975, 2006 | 353 | 2006 |
Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production H Cao, M Sekiya, ME Ertunc, MF Burak, JR Mayers, A White, K Inouye, ... Cell metabolism 17 (5), 768-778, 2013 | 265 | 2013 |
The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans A Tirosh, ES Calay, G Tuncman, KC Claiborn, KE Inouye, K Eguchi, ... Science translational medicine 11 (489), eaav0120, 2019 | 226 | 2019 |
Development of a therapeutic monoclonal antibody that targets secreted fatty acid–binding protein aP2 to treat type 2 diabetes MF Burak, KE Inouye, A White, A Lee, G Tuncman, ES Calay, M Sekiya, ... Science translational medicine 7 (319), 319ra205-319ra205, 2015 | 97 | 2015 |
Intercellular transmission of hepatic ER stress in obesity disrupts systemic metabolism A Tirosh, G Tuncman, ES Calay, M Rathaus, I Ron, A Tirosh, A Yalcin, ... Cell Metabolism 33 (2), 319-333. e6, 2021 | 64 | 2021 |
Divergent roles for p55 and p75 TNF-α receptors in the induction of plasminogen activator inhibitor-1 M Pandey, G Tuncman, GS Hotamisligil, F Samad The American journal of pathology 162 (3), 933-941, 2003 | 57 | 2003 |
Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia S Peller, R Yona, Y Kopilova, M Prokocimer, N Goldfinger, A Uysal, ... Genes, Chromosomes and Cancer 21 (1), 2-7, 1998 | 29 | 1998 |
Null alleles of the aldolase B gene in patients with hereditary fructose intolerance. M Ali, G Tuncman, NC Cross, M Vidailhet, I Bökesoy, R Gitzelmann, ... Journal of medical genetics 31 (6), 499-503, 1994 | 21 | 1994 |
948 Gorgun C, Glimcher LH, and Hotamisligil GS U Ozcan, Q Cao, E Yilmaz, AH Lee, NN Iwakoshi, E Ozdelen, G Tuncman Endoplasmic reticulum stress links 949, 457-461, 0 | 9 | |
OR01-1: Leveraging Immunometabolic Control to Prevent and Treat Obesity Related Asthma MF Burak, N Dagtekin, P Bejo, E Vaillancourt, L Liu, C Gorgun, E Rimm, ... Journal of the Endocrine Society 3 (Supplement_1), OR01-1, 2019 | 1 | 2019 |
FABP4 as a Therapeutic Host Target Controlling SARS-CoV2 Infection H Baazim, E Koyuncu, G Tuncman, MF Burak, L Merkel, N Bahour, ... bioRxiv, 2024.02. 10.579717, 2024 | | 2024 |
COMPOUNDS USEFUL TO TREAT METABOLIC DISORDERS GS Hotamisligil, E Calay, A Tirosh, G Tuncman, M Sekiya US Patent App. 16/937,316, 2021 | | 2021 |
Compounds useful to treat metabolic disorders GS Hotamisligil, E Calay, A Tirosh, G Tuncman, M Sekiya US Patent App. 16/228,297, 2019 | | 2019 |
The Effects of the Common Food Preservative Propionic Acid on Postprandial Metabolism and Body Weight A Tirosh, ES Calay, G Tuncman, KC Claiborn, K Eguchi, M Rathaus, I Ron, ... DIABETES 66, A522-A522, 2017 | | 2017 |