Edoardo Gaude
Edoardo Gaude
POCKiT diagnostics Ltd
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ...
Nature 515 (7527), 431-435, 2014
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
ET Chouchani, VR Pell, E Gaude, D Aksentijević, SY Sundier, EL Robb, ...
Nature 515 (7527), 431-435, 2014
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
The stem cell secretome and its role in brain repair
D Drago, C Cossetti, N Iraci, E Gaude, G Musco, A Bachi, S Pluchino
Biochimie 95 (12), 2271-2285, 2013
Mutant Kras copy number defines metabolic reprogramming and therapeutic susceptibilities
EM Kerr, E Gaude, FK Turrell, C Frezza, CP Martins
Nature 531 (7592), 110-113, 2016
Defects in mitochondrial metabolism and cancer
E Gaude, C Frezza
Cancer & metabolism 2 (1), 1-9, 2014
Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
E Gaude, C Frezza
Nature communications 7 (1), 13041, 2016
Fumarate induces redox-dependent senescence by modifying glutathione metabolism
L Zheng, S Cardaci, L Jerby, ED MacKenzie, M Sciacovelli, TI Johnson, ...
Nature communications 6 (1), 6001, 2015
Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo
PA Gammage, C Viscomi, ML Simard, ASH Costa, E Gaude, CA Powell, ...
Nature medicine 24 (11), 1691-1695, 2018
Germline FH Mutations Presenting With Pheochromocytoma
GR Clark, M Sciacovelli, E Gaude, DM Walsh, G Kirby, MA Simpson, ...
The Journal of Clinical Endocrinology & Metabolism 99 (10), E2046-E2050, 2014
NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction
E Gaude, C Schmidt, PA Gammage, A Dugourd, T Blacker, SP Chew, ...
Molecular cell 69 (4), 581-593. e7, 2018
Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer
K Yizhak, E Gaude, S Le Dévédec, YY Waldman, GY Stein, ...
Elife 3, e03641, 2014
A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients
D Rodenhizer, E Gaude, D Cojocari, R Mahadevan, C Frezza, ...
Nature materials 15 (2), 227-234, 2016
The metabolic alterations of cancer cells
M Sciacovelli, E Gaude, M Hilvo, C Frezza
Methods in enzymology 542, 1-23, 2014
Safety and efficacy of transcranial direct current stimulation in acute experimental ischemic stroke
L Peruzzotti-Jametti, M Cambiaghi, M Bacigaluppi, M Gallizioli, E Gaude, ...
Stroke 44 (11), 3166-3174, 2013
Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death
D Catanzaro, E Gaude, G Orso, C Giordano, G Guzzo, A Rasola, ...
Oncotarget 6 (30), 30102, 2015
Extracellular vesicles are independent metabolic units with asparaginase activity
N Iraci, E Gaude, T Leonardi, ASH Costa, C Cossetti, L Peruzzotti-Jametti, ...
Nature chemical biology 13 (9), 951-955, 2017
Near-complete elimination of mutant mtDNA by iterative or dynamic dose-controlled treatment with mtZFNs
PA Gammage, E Gaude, L Van Haute, P Rebelo-Guiomar, CB Jackson, ...
Nucleic acids research 44 (16), 7804-7816, 2016
Integrated pharmacodynamic analysis identifies two metabolic adaption pathways to metformin in breast cancer
SR Lord, WC Cheng, D Liu, E Gaude, S Haider, T Metcalf, N Patel, ...
Cell metabolism 28 (5), 679-688. e4, 2018
muma, an R package for metabolomics univariate and multivariate statistical analysis
E Gaude, F Chignola, D Spiliotopoulos, A Spitaleri, M Ghitti, ...
Current Metabolomics 1 (2), 180-189, 2013
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Articles 1–20