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Tim E. Moors
Tim E. Moors
Postdoctoral Research Fellow, Harvard Medical School and Brigham and Women's Hospital
Verified email at bwh.harvard.edu
Title
Cited by
Cited by
Year
Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, TE Moors, PP Navarro, ...
Nature neuroscience 22 (7), 1099-1109, 2019
7372019
Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease
TE Moors, JJM Hoozemans, A Ingrassia, T Beccari, L Parnetti, ...
Molecular neurodegeneration 12, 1-18, 2017
3002017
Microglial phenotypes and toll-like receptor 2 in the substantia nigra and hippocampus of incidental Lewy body disease cases and Parkinson’s disease patients
KJ Doorn, T Moors, B Drukarch, WDJ van de Berg, PJ Lucassen, ...
Acta neuropathologica communications 2, 1-17, 2014
2952014
Lysosomal dysfunction and α‐Synuclein aggregation in Parkinson's disease: diagnostic links
T Moors, S Paciotti, D Chiasserini, P Calabresi, L Parnetti, T Beccari, ...
Movement Disorders 31 (6), 791-801, 2016
1502016
Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson’s Disease and Dementia with Lewy Bodies
TE Moors, S Paciotti, A Ingrassia, M Quadri, G Breedveld, A Tasegian, ...
Molecular neurobiology 56, 1344-1355, 2019
1212019
The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
Acta neuropathologica 142, 423-448, 2021
772021
Path mediation analysis reveals GBA impacts Lewy body disease status by increasing α-synuclein levels
AL Gündner, G Duran-Pacheco, S Zimmermann, I Ruf, T Moors, ...
Neurobiology of disease 121, 205-213, 2019
552019
Lewy pathology in Parkinson’s disease consists of a crowded organellar, membranous medley
SH Shahmoradian, AJ Lewis, C Genoud, J Hench, T Moors, PP Navarro, ...
biorxiv, 137976, 2017
332017
Wild-type GBA1 increases the α-synuclein tetramer–monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice
KE Glajch, TE Moors, Y Chen, PA Bechade, AY Nam, MM Rajsombath, ...
Proceedings of the National Academy of Sciences 118 (31), e2103425118, 2021
242021
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity
N Ramalingam, SX Jin, TE Moors, L Fonseca-Ornelas, K Shimanaka, ...
npj Parkinson's Disease 9 (1), 4, 2023
212023
Subcellular orchestration of alpha-synuclein variants in Parkinson’s disease brains revealed by 3D multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
bioRxiv, 470476, 2018
122018
Detailed structural orchestration of Lewy pathology in Parkinson’s disease as revealed by 3D multicolor STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
Biorxiv, 470476, 2018
122018
The orchestration of subcellular alpha-synuclein pathology in the Parkinson’s disease brain revealed by STED microscopy
TE Moors, CA Maat, D Niedieker, D Mona, D Petersen, ...
bioRxiv, 2018
92018
Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies
TE Moors, D Mona, S Luehe, G Duran-Pacheco, L Spycher, O Mundigl, ...
Acta neuropathologica communications 10 (1), 82, 2022
82022
Origin of α-mannosidase activity in CSF
A Tasegian, S Paciotti, MR Ceccarini, M Codini, T Moors, D Chiasserini, ...
The international journal of biochemistry & cell biology 87, 34-37, 2017
72017
Lewy pathology in Parkinson’s disease consists of a crowded organellar membranous medley. bioRxiv 137976
SH Shahmoradian, C Genoud, A Graff-Meyer, J Hench, T Moors, ...
72017
Alterations in sub-axonal architecture between normal aging and Parkinson’s diseased human brains using label-free cryogenic X-ray nanotomography
HT Tran, EHR Tsai, AJ Lewis, T Moors, J Bol, I Rostami, A Diaz, AJ Jonker, ...
Frontiers in neuroscience 14, 570019, 2020
52020
Increased palmitoylation improves estrogen receptor alpha–dependent hippocampal synaptic deficits in a mouse model of synucleinopathy
TE Moors, S Li, TD McCaffery, GPH Ho, PA Bechade, LN Pham, ...
Science Advances 9 (46), eadj1454, 2023
22023
Altered TFEB subcellular localization in nigral neurons of subjects with incidental, sporadic and GBA-related Lewy body diseases
TE Moors, ML Morella, C Bertran-Cobo, H Geut, V Udayar, ...
Acta Neuropathologica 147 (1), 67, 2024
2024
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson’s disease phenotypes
S Nuber, X Zhang, TD McCaffery, TE Moors, MA Adom, WN Hahn, ...
npj Parkinson's Disease 10 (1), 47, 2024
2024
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