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Sylvia Fernandez Boj
Sylvia Fernandez Boj
Hubrecht Orgaoid Technology
Verified email at huborganoids.nl - Homepage
Title
Cited by
Cited by
Year
Organoid models of human and mouse ductal pancreatic cancer
SF Boj, CI Hwang, LA Baker, IIC Chio, DD Engle, V Corbo, M Jager, ...
Cell 160 (1), 324-338, 2015
18962015
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
M Huch, C Dorrell, SF Boj, JH Van Es, VSW Li, M Van De Wetering, ...
Nature 494 (7436), 247-250, 2013
15612013
A living biobank of breast cancer organoids captures disease heterogeneity
N Sachs, J De Ligt, O Kopper, E Gogola, G Bounova, F Weeber, ...
Cell 172 (1), 373-386. e10, 2018
14702018
Long‐term expanding human airway organoids for disease modeling
N Sachs, A Papaspyropoulos, DD Zomer‐van Ommen, I Heo, L Böttinger, ...
The EMBO journal 38 (4), e100300, 2019
7712019
Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis
M Huch, P Bonfanti, SF Boj, T Sato, CJM Loomans, M Van De Wetering, ...
The EMBO journal 32 (20), 2708-2721, 2013
7052013
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
L Broutier, A Andersson-Rolf, CJ Hindley, SF Boj, H Clevers, BK Koo, ...
Nature protocols 11 (9), 1724-1743, 2016
6632016
Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene
ER Pearson, SF Boj, AM Steele, T Barrett, K Stals, JP Shield, S Ellard, ...
PLoS medicine 4 (4), e118, 2007
5292007
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening
E Driehuis, A Van Hoeck, K Moore, S Kolders, HE Francies, ...
Proceedings of the National Academy of Sciences 116 (52), 26580-26590, 2019
3322019
A transcription factor regulatory circuit in differentiated pancreatic cells
SF Boj, M Párrizas, MA Maestro, J Ferrer
Proceedings of the National Academy of Sciences 98 (25), 14481-14486, 2001
3062001
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60-68, 2017
3032017
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ...
Molecular and cellular biology, 2012
2972012
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand
SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ...
Cell 151 (7), 1595-1607, 2012
2472012
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas
MA Maestro, SF Boj, RF Luco, CE Pierreux, J Cabedo, JM Servitja, ...
Human molecular genetics 12 (24), 3307-3314, 2003
1962003
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
ACF Bolhaqueiro, B Ponsioen, B Bakker, SJ Klaasen, E Kucukkose, ...
Nature genetics 51 (5), 824-834, 2019
1902019
CRISPR-based adenine editors correct nonsense mutations in a cystic fibrosis organoid biobank
MH Geurts, E de Poel, GD Amatngalim, R Oka, FM Meijers, ...
Cell stem cell 26 (4), 503-510. e7, 2020
1682020
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ...
Cell Stem Cell 28 (5), 816-832, 2021
1642021
Hepatic nuclear factor 1-α directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets
M Párrizas, MA Maestro, SF Boj, A Paniagua, R Casamitjana, R Gomis, ...
Molecular and cellular biology 21 (9), 3234-3243, 2001
1602001
Hnf1α (MODY3) controls tissue-specific transcriptional programs and exerts opposed effects on cell growth in pancreatic islets and liver
JM Servitja, M Pignatelli, MA Maestro, C Cardalda, SF Boj, J Lozano, ...
Molecular and cellular biology 29 (11), 2945-2959, 2009
1502009
Genetic evidence that HNF-1α–dependent transcriptional control of HNF-4α is essential for human pancreatic β cell function
SK Hansen, M Párrizas, ML Jensen, S Pruhova, J Ek, SF Boj, A Johansen, ...
The Journal of clinical investigation 110 (6), 827-833, 2002
1462002
Distinct roles of HNF1 Β, HNF1 α, and HNF4 α in regulating pancreas development, Β-cell function and growth
MA Maestro, C Cardalda, SF Boj, RF Luco, JM Servitja, J Ferrer
Development of the Pancreas and Neonatal Diabetes 12, 33-45, 2007
1392007
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