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Extracellular vesicles: biology and emerging therapeutic opportunities
S El Andaloussi, I Mäger, XO Breakefield, MJA Wood
Nature reviews Drug discovery 12 (5), 347-357, 2013
29922013
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
OPB Wiklander, JZ Nordin, A O'Loughlin, Y Gustafsson, G Corso, I Mäger, ...
Journal of extracellular vesicles 4 (1), 26316, 2015
12862015
Cells release subpopulations of exosomes with distinct molecular and biological properties
E Willms, HJ Johansson, I Mäger, Y Lee, KEM Blomberg, M Sadik, ...
Scientific reports 6 (1), 22519, 2016
9422016
Methodological guidelines to study extracellular vesicles
FAW Coumans, AR Brisson, EI Buzas, F Dignat-George, EEE Drees, ...
Circulation research 120 (10), 1632-1648, 2017
9152017
Extracellular vesicle heterogeneity: subpopulations, isolation techniques, and diverse functions in cancer progression
E Willms, C Cabañas, I Mäger, MJA Wood, P Vader
Frontiers in immunology 9, 355368, 2018
8042018
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper
B Mateescu, EJK Kowal, BWM van Balkom, S Bartel, SN Bhattacharyya, ...
Journal of extracellular vesicles 6 (1), 1286095, 2017
6942017
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
JZ Nordin, Y Lee, P Vader, I Mäger, HJ Johansson, W Heusermann, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (4), 879-883, 2015
6572015
Isolation of exosomes from blood plasma: qualitative and quantitative comparison of ultracentrifugation and size exclusion chromatography methods
T Baranyai, K Herczeg, Z Onódi, I Voszka, K Módos, N Marton, G Nagy, ...
PloS one 10 (12), e0145686, 2015
6312015
Exosomes for targeted siRNA delivery across biological barriers
SEL Andaloussi, S Lakhal, I Mäger, MJA Wood
Advanced drug delivery reviews 65 (3), 391-397, 2013
5312013
Extracellular vesicles in neurodegenerative disease—pathogenesis to biomarkers
AG Thompson, E Gray, SM Heman-Ackah, I Mäger, K Talbot, ...
Nature Reviews Neurology 12 (6), 346-357, 2016
3412016
Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo
S El Andaloussi, T Lehto, I Mäger, K Rosenthal-Aizman, II Oprea, ...
Nucleic acids research 39 (9), 3972-3987, 2011
3262011
Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography
G Corso, I Mäger, Y Lee, A Görgens, J Bultema, B Giebel, MJA Wood, ...
Scientific reports 7 (1), 11561, 2017
2002017
Therapeutic potential of multipotent mesenchymal stromal cells and their extracellular vesicles
N Heldring, I Mäger, MJA Wood, K Le Blanc, SEL Andaloussi
Human gene therapy 26 (8), 506-517, 2015
1982015
Functional delivery of lipid-conjugated siRNA by extracellular vesicles
AJ O’Loughlin, I Mäger, OG de Jong, MA Varela, RM Schiffelers, ...
Molecular Therapy 25 (7), 1580-1587, 2017
1852017
In vivo biodistribution and efficacy of peptide mediated delivery
P Järver, I Mäger, Ü Langel
Trends in pharmacological sciences 31 (11), 528-535, 2010
1772010
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles
J Li, Y Lee, HJ Johansson, I Mäger, P Vader, JZ Nordin, OPB Wiklander, ...
Journal of extracellular vesicles 4 (1), 26883, 2015
1722015
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia
Y Aoki, R Manzano, Y Lee, R Dafinca, M Aoki, AGL Douglas, MA Varela, ...
Brain 140 (4), 887-897, 2017
1692017
Delivery of nucleic acids with a stearylated (RxR) 4 peptide using a non-covalent co-incubation strategy
T Lehto, R Abes, N Oskolkov, J Suhorutšenko, DM Copolovici, I Mäger, ...
Journal of Controlled Release 141 (1), 42-51, 2010
1512010
Sensitive and rapid detection of Chlamydia trachomatis by recombinase polymerase amplification directly from urine samples
K Krõlov, J Frolova, O Tudoran, J Suhorutsenko, T Lehto, H Sibul, I Mäger, ...
The Journal of Molecular Diagnostics 16 (1), 127-135, 2014
1482014
A peptide-based vector for efficient gene transfer in vitro and in vivo
T Lehto, OE Simonson, I Mäger, K Ezzat, H Sork, DM Copolovici, JR Viola, ...
Molecular Therapy 19 (8), 1457-1467, 2011
1372011
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Artikelen 1–20