Jeroen van de Peppel
Jeroen van de Peppel
Erasmus MC
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A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells
AMC Barradas, HAM Fernandes, N Groen, YC Chai, J Schrooten, ...
Biomaterials 33 (11), 3205-3215, 2012
Life-course genome-wide association study meta-analysis of total body BMD and assessment of age-specific effects
C Medina-Gomez, JP Kemp, K Trajanoska, J Luan, A Chesi, TS Ahluwalia, ...
The American Journal of Human Genetics 102 (1), 88-102, 2018
Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets
J van de Peppel, N Kettelarij, H van Bakel, TTJP Kockelkorn, ...
Molecular cell 19 (4), 511-522, 2005
MicroRNA functions in osteogenesis and dysfunctions in osteoporosis
AJ Van Wijnen, J Van De Peppel, JP Van Leeuwen, JB Lian, GS Stein, ...
Current osteoporosis reports 11, 72-82, 2013
Monitoring global messenger RNA changes in externally controlled microarray experiments
J van de Peppel, P Kemmeren, H van Bakel, M Radonjic, D van Leenen, ...
EMBO reports 4 (4), 387-393, 2003
Genome-wide location of the coactivator mediator: Binding without activation and transient Cdk8 interaction on DNA
JC Andrau, L van de Pasch, P Lijnzaad, T Bijma, MG Koerkamp, ...
Molecular cell 22 (2), 179-192, 2006
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course
M Graff, JS Ngwa, T Workalemahu, G Homuth, S Schipf, A Teumer, ...
Human molecular genetics 22 (17), 3597-3607, 2013
Vitamin D and gene networks in human osteoblasts
J van de Peppel, JPTM van Leeuwen
Frontiers in Physiology 5, 137, 2014
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment
JP Kemp, C Medina-Gomez, K Estrada, B St Pourcain, DHM Heppe, ...
PLoS genetics 10 (6), e1004423, 2014
Calcifying vascular smooth muscle cells and osteoblasts: independent cell types exhibiting extracellular matrix and biomineralization-related mimicries
RDAM Alves, M Eijken, J van de Peppel, JPTM van Leeuwen
BMC genomics 15, 1-14, 2014
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway
AM Brum, J van de Peppel, CS Van Der Leije, M Schreuders-Koedam, ...
Proceedings of the National Academy of Sciences 112 (41), 12711-12716, 2015
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone
C Bruedigam, M Eijken, M Koedam, J Van De Peppel, K Drabek, H Chiba, ...
Stem cells 28 (5), 916-927, 2010
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
C Medina-Gomez, JP Kemp, NL Dimou, E Kreiner, A Chesi, BS Zemel, ...
Nature communications 8 (1), 121, 2017
Identification of three early phases of cell-fate determination during osteogenic and adipogenic differentiation by transcription factor dynamics
J van de Peppel, T Strini, J Tilburg, H Westerhoff, AJ van Wijnen, ...
Stem cell reports 8 (4), 947-960, 2017
Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth
J Morhayim, J van de Peppel, JAA Demmers, G Kocer, AL Nigg, ...
The FASEB Journal 29 (1), 274-285, 2015
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses
C Bruedigam, M Driel, M Koedam, J Peppel, BCJ van der Eerden, ...
Current protocols in stem cell biology 17 (1), 1H. 3.1-1H. 3.20, 2011
GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release
K Drabek, J van de Peppel, M Eijken, JPTM van Leeuwen
Journal of Bone and Mineral Research 26 (9), 2045-2051, 2011
Human memory Th17 cell populations change into anti-inflammatory cells with regulatory capacity upon exposure to active vitamin D
W Dankers, N Davelaar, JP Van Hamburg, J Van De Peppel, EM Colin, ...
Frontiers in immunology 10, 1504, 2019
Pro-osteogenic trophic effects by PKA activation in human mesenchymal stromal cells
J Doorn, J van de Peppel, JPTM van Leeuwen, N Groen, ...
Biomaterials 32 (26), 6089-6098, 2011
Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns
NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga, L Pieuchot, K Anselme, ...
Scientific reports 9 (1), 9099, 2019
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