| LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 310 | 2022 |
| Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA M Alami, K Dalal, B Lelj‐Garolla, SG Sligar, F Duong The EMBO journal 26 (8), 1995-2004, 2007 | 185 | 2007 |
| Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling BD Fonseca, GH Diering, MA Bidinosti, K Dalal, T Alain, AD Balgi, ... Journal of Biological Chemistry 287 (21), 17530-17545, 2012 | 158 | 2012 |
| Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer K Dalal, M Roshan-Moniri, A Sharma, H Li, F Ban, M Hessein, M Hsing, ... Journal of biological chemistry 289 (38), 26417-26429, 2014 | 141 | 2014 |
| Discovery of small-molecule inhibitors selectively targeting the DNA-binding domain of the human androgen receptor H Li, F Ban, K Dalal, E Leblanc, K Frewin, D Ma, H Adomat, PS Rennie, ... Journal of medicinal chemistry 57 (15), 6458-6467, 2014 | 137 | 2014 |
| Best practices of computer-aided drug discovery: lessons learned from the development of a preclinical candidate for prostate cancer with a new mechanism of action F Ban, K Dalal, H Li, E LeBlanc, PS Rennie, A Cherkasov Journal of chemical information and modeling 57 (5), 1018-1028, 2017 | 109 | 2017 |
| Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer N Lallous, K Dalal, A Cherkasov, PS Rennie International journal of molecular sciences 14 (6), 12496-12519, 2013 | 82 | 2013 |
| Moving towards precision urologic oncology: targeting enzalutamide-resistant prostate cancer and mutated forms of the androgen receptor using the novel inhibitor darolutamide … H Borgmann, N Lallous, D Ozistanbullu, E Beraldi, N Paul, K Dalal, L Fazli, ... European urology 73 (1), 4-8, 2018 | 78 | 2018 |
| RPA nucleic acid-binding properties of IFI16-HIN200 H Yan, K Dalal, BK Hon, P Youkharibache, D Lau, F Pio Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (7-8), 1087 …, 2008 | 68 | 2008 |
| Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase K Dalal, CS Chan, SG Sligar, F Duong Proceedings of the National Academy of Sciences 109 (11), 4104-4109, 2012 | 62 | 2012 |
| SecYEG activates GTPases to drive the completion of cotranslational protein targeting D Akopian, K Dalal, K Shen, F Duong, S Shan Journal of Cell Biology 200 (4), 397-405, 2013 | 57 | 2013 |
| Androgen receptor-binding sites are highly mutated in prostate cancer T Morova, DR McNeill, N Lallous, M Gönen, K Dalal, DM Wilson III, ... Nature communications 11 (1), 832, 2020 | 51 | 2020 |
| Structure, binding, and activity of Syd, a SecY-interacting protein K Dalal, N Nguyen, M Alami, J Tan, TF Moraes, WC Lee, R Maurus, ... Journal of Biological Chemistry 284 (12), 7897-7902, 2009 | 50 | 2009 |
| Selectively targeting the dimerization interface of human androgen receptor with small-molecules to treat castration-resistant prostate cancer K Dalal, F Ban, H Li, H Morin, M Roshan-Moniri, KJ Tam, A Shepherd, ... Cancer Letters 437, 35-43, 2018 | 49 | 2018 |
| Discovery and characterization of small molecules targeting the DNA-binding ETS domain of ERG in prostate cancer MS Butler, M Roshan-Moniri, M Hsing, D Lau, A Kim, P Yen, M Mroczek, ... Oncotarget 8 (26), 42438, 2017 | 43 | 2017 |
| Reconstitution of the SecY translocon in nanodiscs K Dalal, F Duong Protein Secretion: Methods and Protocols, 145-156, 2010 | 39 | 2010 |
| The maltose ABC transporter: action of membrane lipids on the transporter stability, coupling and ATPase activity H Bao, K Dalal, V Wang, I Rouiller, F Duong Biochimica Et Biophysica Acta (BBA)-Biomembranes 1828 (8), 1723-1730, 2013 | 38 | 2013 |
| Bypassing drug resistance mechanisms of prostate cancer with small molecules that target androgen Receptor–Chromatin interactions K Dalal, M Che, NS Que, A Sharma, R Yang, N Lallous, H Borgmann, ... Molecular cancer therapeutics 16 (10), 2281-2291, 2017 | 33 | 2017 |
| The SecY complex: conducting the orchestra of protein translocation K Dalal, F Duong Trends in cell biology 21 (9), 506-514, 2011 | 30 | 2011 |
| The SecY complex forms a channel capable of ionic discrimination K Dalal, F Duong EMBO reports 10 (7), 762-768, 2009 | 30 | 2009 |
Artem CherkasovUniversity of British ColumbiaVerified email at interchange.ubc.ca
