Ardy van Helvoort
Ardy van Helvoort
Director Research Neuroscience, Muscle & Nutrition; Associate Professor Medical Nutrition
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TitleCited byYear
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine
A van Helvoort, AJ Smith, H Sprong, I Fritzsche, AH Schinkel, P Borst, ...
Cell 87 (3), 507-517, 1996
ABC transporters in lipid transport
P Borst, N Zelcer, A Van Helvoort
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping
AJ Smith, A Van Helvoort, G Van Meer, K Szabó, E Welker, G Szakács, ...
Journal of Biological Chemistry 275 (31), 23530-23539, 2000
Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies
GL Scheffer, M Kool, M Heijn, M de Haas, ACLM Pijnenborg, J Wijnholds, ...
Cancer research 60 (18), 5269-5277, 2000
The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane
RJ Raggers, A van Helvoort, R Evers, G van Meer
Journal of Cell Science 112 (3), 415-422, 1999
Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food
NEP Deutz, A Safar, S Schutzler, R Memelink, A Ferrando, H Spencer, ...
Clinical nutrition 30 (6), 759-768, 2011
Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement
FH Schröder, MJ Roobol, ER Boevé, R de Mutsert, ...
European urology 48 (6), 922-931, 2005
Transport of sphingomyelin to the cell surface is inhibited by brefeldin A and in mitosis, where C6-NBD-sphingomyelin is translocated across the plasma membrane by a multidrug …
A van Helvoort, ML Giudici, M Thielemans, G van Meer
Journal of cell science 110 (1), 75-83, 1997
Conversion of diacylglycerol to phosphatidylcholine on the basolateral surface of epithelial (Madin-Darby canine kidney) cells. Evidence for the reverse action of a …
A Van Helvoort, W Van't Hof, T Ritsema, A Sandra, G Van Meer
Journal of Biological Chemistry 269 (3), 1763-1769, 1994
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice
K Van Norren, D Kegler, JM Argiles, Y Luiking, M Gorselink, A Laviano, ...
British journal of cancer 100 (5), 713-722, 2009
Direct effects of doxorubicin on skeletal muscle contribute to fatigue
K Van Norren, A Van Helvoort, JM Argilés, S Van Tuijl, K Arts, M Gorselink, ...
British journal of cancer 100 (2), 311-314, 2009
Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces
A van Helvoort, A de Brouwer, R Ottenhoff, JFHM Brouwers, J Wijnholds, ...
Proceedings of the National Academy of Sciences 96 (20), 11501-11506, 1999
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells.
K Sandvig, O Garred, A Van Helvoort, G Van Meer, B Van Deurs
Molecular biology of the cell 7 (9), 1391-1404, 1996
Supplementation with a fish oil-enriched, high-protein medical food leads to rapid incorporation of EPA into white blood cells and modulates immune responses within one week in …
J Faber, M Berkhout, AP Vos, JWC Sijben, PC Calder, J Garssen, ...
The Journal of nutrition 141 (5), 964-970, 2011
A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD
C Bool, E Rutten, A Helvoort, FME Franssen, EFM Wouters, AMWJ Schols
Journal of Cachexia, Sarcopenia and Muscle 8 (5), 748–758, 2017
Intracellular lipid heterogeneity caused by topology of synthesis and specificity in transport. Example: sphingolipids
A van Helvoort, G van Meer
FEBS letters 369 (1), 18-21, 1995
Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia
J Faber, P Vos, D Kegler, K Van Norren, JM Argiles, A Laviano, J Garssen, ...
British journal of cancer 99 (12), 2029-2036, 2008
Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice
SJ Peters, A Van Helvoort, D Kegler, JM Argiles, YC Luiking, A Laviano, ...
Oncology reports 26 (1), 247-254, 2011
Mass‐dependent decline of skeletal muscle function in cancer cachexia
M Gorselink, SFC Vaessen, LG van der Flier, I Leenders, D Kegler, ...
Muscle & Nerve: Official Journal of the American Association of …, 2006
Improved body weight and performance status and reduced serum PGE2 levels after nutritional intervention with a specific medical food in newly diagnosed …
J Faber, MJ Uitdehaag, M Spaander, S van Steenbergen‐Langeveld, ...
Journal of cachexia, sarcopenia and muscle 6 (1), 32-44, 2015
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