Crystal structure of a Baeyer–Villiger monooxygenase E Malito, A Alfieri, MW Fraaije, A Mattevi Proceedings of the National Academy of Sciences 101 (36), 13157-13162, 2004 | 361 | 2004 |
Self-assembling protein nanoparticles in the design of vaccines J López-Sagaseta, E Malito, R Rappuoli, MJ Bottomley Computational and structural biotechnology journal 14, 58-68, 2016 | 346 | 2016 |
Amyloid β-degrading cryptidases: insulin degrading enzyme, presequence peptidase, and neprilysin E Malito, RE Hulse, WJ Tang Cellular and Molecular Life Sciences 65, 2574-2585, 2008 | 228 | 2008 |
Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase A Alfieri, E Malito, R Orru, MW Fraaije, A Mattevi Proceedings of the National Academy of Sciences 105 (18), 6572-6577, 2008 | 179 | 2008 |
Rational design of a meningococcal antigen inducing broad protective immunity M Scarselli, B Aricò, B Brunelli, S Savino, F Di Marcello, E Palumbo, ... Science translational medicine 3 (91), 91ra62-91ra62, 2011 | 164 | 2011 |
Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197 E Malito, B Bursulaya, C Chen, PL Surdo, M Picchianti, E Balducci, ... Proceedings of the National Academy of Sciences 109 (14), 5229-5234, 2012 | 162 | 2012 |
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen E Malito, A Faleri, P Lo Surdo, D Veggi, G Maruggi, E Grassi, E Cartocci, ... Proceedings of the National Academy of Sciences 110 (9), 3304-3309, 2013 | 148 | 2013 |
Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE H Im, M Manolopoulou, E Malito, Y Shen, J Zhao, M Neant-Fery, CY Sun, ... Journal of biological chemistry 282 (35), 25453-25463, 2007 | 146 | 2007 |
Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin MA Leissring, E Malito, S Hedouin, L Reinstatler, T Sahara, SO Abdul-Hay, ... PloS one 5 (5), e10504, 2010 | 132 | 2010 |
Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis RW Bourdeau, E Malito, A Chenal, BL Bishop, MW Musch, ML Villereal, ... Journal of Biological Chemistry 284 (21), 14645-14656, 2009 | 111 | 2009 |
Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme E Malito, LA Ralat, M Manolopoulou, JL Tsay, NL Wadlington, WJ Tang Biochemistry 47 (48), 12822-12834, 2008 | 102 | 2008 |
Structural and computational biology in the design of immunogenic vaccine antigens L Liljeroos, E Malito, I Ferlenghi, MJ Bottomley Journal of immunology research 2015, 2015 | 97 | 2015 |
Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme M Manolopoulou, Q Guo, E Malito, AB Schilling, WJ Tang Journal of biological chemistry 284 (21), 14177-14188, 2009 | 96 | 2009 |
Structures of Michaelis and product complexes of plant cytokinin dehydrogenase: implications for flavoenzyme catalysis E Malito, A Coda, KD Bilyeu, MW Fraaije, A Mattevi Journal of molecular biology 341 (5), 1237-1249, 2004 | 95 | 2004 |
Elucidation of human choline kinase crystal structures in complex with the products ADP or phosphocholine E Malito, N Sekulic, WCS Too, M Konrad, A Lavie Journal of molecular biology 364 (2), 136-151, 2006 | 91 | 2006 |
Structural basis for potent antibody-mediated neutralization of human cytomegalovirus S Chandramouli, E Malito, TV Nguyen, K Luisi, D Donnarumma, Y Xing, ... Science immunology 2 (12), eaan1457, 2017 | 89 | 2017 |
Modular total chemical synthesis of a human immunodeficiency virus type 1 protease ECB Johnson, E Malito, Y Shen, D Rich, WJ Tang, SBH Kent Journal of the American Chemical Society 129 (37), 11480-11490, 2007 | 82 | 2007 |
Supramolecular organization of the repetitive backbone unit of the Streptococcus pneumoniae pilus G Spraggon, E Koesema, M Scarselli, E Malito, M Biagini, N Norais, ... PloS one 5 (6), e10919, 2010 | 72 | 2010 |
Protein crystallography in vaccine research and development E Malito, A Carfi, MJ Bottomley International Journal of Molecular Sciences 16 (6), 13106-13140, 2015 | 70 | 2015 |
Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide F Carboni, R Adamo, M Fabbrini, R De Ricco, V Cattaneo, B Brogioni, ... Proceedings of the National Academy of Sciences 114 (19), 5017-5022, 2017 | 68 | 2017 |