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Charles Fulco
Charles Fulco
Verified email at sanofi.com
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Year
Perturb-seq: dissecting molecular circuits with scalable single-cell RNA profiling of pooled genetic screens
A Dixit, O Parnas, B Li, J Chen, CP Fulco, L Jerby-Arnon, ND Marjanovic, ...
Cell 167 (7), 1853-1866. e17, 2016
13822016
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
CP Fulco, J Nasser, TR Jones, G Munson, DT Bergman, V Subramanian, ...
Nature Genetics 51 (12), 1664-1669, 2019
7012019
Systematic mapping of functional enhancer–promoter connections with CRISPR interference
CP Fulco, M Munschauer, R Anyoha, G Munson, SR Grossman, EM Perez, ...
Science 354 (6313), 769-773, 2016
5972016
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ...
Nature 586 (7831), 763-768, 2020
4792020
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ...
Nature 548, 343-346, 2017
4032017
Genome-wide enhancer maps link risk variants to disease genes
J Nasser, DT Bergman, CP Fulco, P Guckelberger, BR Doughty, ...
Nature 593 (7858), 238-243, 2021
3962021
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
M Munschauer, CT Nguyen, K Sirokman, CR Hartigan, L Hogstrom, ...
Nature 561 (7721), 132-136, 2018
3572018
Ribosome levels selectively regulate translation and lineage commitment in human hematopoiesis
RK Khajuria, M Munschauer, JC Ulirsch, C Fiorini, LS Ludwig, ...
Cell 173 (1), 90-103. e19, 2018
3562018
Cycling cancer persister cells arise from lineages with distinct programs
Y Oren, M Tsabar, MS Cuoco, L Amir-Zilberstein, HF Cabanos, JC Hütter, ...
Nature 596 (7873), 576-582, 2021
2742021
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases
EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ...
Nature Genetics 55 (8), 1267-1276, 2023
1392023
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity
S Gazal, O Weissbrod, F Hormozdiari, KK Dey, J Nasser, KA Jagadeesh, ...
Nature Genetics, 1-10, 2022
872022
Compatibility rules of human enhancer and promoter sequences
DT Bergman, TR Jones, V Liu, J Ray, E Jagoda, L Siraj, HY Kang, ...
Nature 607 (7917), 176-184, 2022
862022
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features
JP Ray, CG de Boer, CP Fulco, CA Lareau, M Kanai, JC Ulirsch, ...
Nature Communications 11 (1), 1-13, 2020
442020
CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data
JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ...
Nature Methods 15, 992-993, 2018
342018
HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes
JL Marshall, BR Doughty, V Subramanian, P Guckelberger, Q Wang, ...
Proceedings of the National Academy of Sciences 117 (52), 33404-33413, 2020
272020
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease
J Dahlqvist, CP Fulco, JP Ray, T Liechti, CG de Boer, DJ Lieb, ...
Human Molecular Genetics 31 (12), 1946-1961, 2022
92022
Rewriting regulatory DNA to dissect and reprogram gene expression
GE Martyn, MT Montgomery, H Jones, K Guo, BR Doughty, J Linder, ...
bioRxiv, 2023.12. 20.572268, 2023
42023
Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma
AR Iyer, A Gurumurthy, R Kodgule, AR Aguilar, T Saari, A Ramzan, ...
bioRxiv, 2023.05. 02.538892, 2023
22023
SYSTEMATIC SCREENING AND MAPPING OF REGULATORY ELEMENTS IN NON-CODING GENOMIC REGIONS, METHODS, COMPOSITIONS, AND APPLICATIONS THEREOF
J Engreitz, ES Lander, C Fulco
US Patent App. 16/337,846, 2020
22020
Novel mechanism of MYC deregulation in Multiple Myeloma
M Rahmat, K Clement, JB Alberge, R Sklavenitis-Pistofidis, R Kodgule, ...
bioRxiv, 2023.05. 19.541506, 2023
2023
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