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Laurens Raes
Laurens Raes
PhD student, Laboratory of General Biochemistry and Physical Pharmacy (Ghent University)
Geverifieerd e-mailadres voor ugent.be
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Photothermal nanofibres enable safe engineering of therapeutic cells
R Xiong, D Hua, J Van Hoeck, D Berdecka, L Léger, S De Munter, ...
Nature nanotechnology 16 (11), 1281-1291, 2021
2122021
Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation
L Raes, S Stremersch, JC Fraire, T Brans, G Goetgeluk, S De Munter, ...
Nano-Micro Letters 12, 1-17, 2020
552020
Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
JC Fraire, G Houthaeve, J Liu, L Raes, L Vermeulen, S Stremersch, ...
Journal of controlled release 319, 262-275, 2020
552020
Non-viral transfection technologies for next-generation therapeutic T cell engineering
L Raes, SC De Smedt, K Raemdonck, K Braeckmans
Biotechnology Advances 49, 107760, 2021
402021
Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells
L Raes, C Van Hecke, J Michiels, S Stremersch, JC Fraire, T Brans, ...
Crystals 9 (8), 411, 2019
342019
Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells
A Harizaj, M Wels, L Raes, S Stremersch, G Goetgeluk, T Brans, ...
Advanced Functional Materials 31 (28), 2102472, 2021
312021
Fluorescence‐based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts
H Zhang, K Rombouts, L Raes, R Xiong, SC De Smedt, K Braeckmans, ...
Advanced biosystems 4 (5), 2000057, 2020
302020
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells
L Van Hoecke, L Raes, S Stremersch, T Brans, JC Fraire, R Roelandt, ...
International Journal of Molecular Sciences 20 (17), 4254, 2019
252019
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering
L Raes, M Pille, A Harizaj, G Goetgeluk, J Van Hoeck, S Stremersch, ...
Molecular Therapy-Nucleic Acids 25, 696-707, 2021
192021
Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles
LMP Vermeulen, JC Fraire, L Raes, E De Meester, S De Keulenaer, ...
International Journal of Molecular Sciences 19 (8), 2400, 2018
172018
Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells
JC Fraire, E Shaabani, M Sharifiaghdam, M Rombaut, C Hinnekens, ...
Nature Communications 13 (1), 1996, 2022
162022
Phase I study of [68Ga] Ga-Anti-CD206-sdAb for PET/CT assessment of protumorigenic macrophage presence in solid tumors (MMR phase I)
O Gondry, C Xavier, L Raes, J Heemskerk, N Devoogdt, H Everaert, ...
Journal of Nuclear Medicine 64 (9), 1378-1384, 2023
102023
Engineering and crystal structure of a monomeric FLT3 ligand variant
E Pannecoucke, L Raes, SN Savvides
Acta Crystallographica Section F: Structural Biology Communications 77 (4 …, 2021
22021
Phase II Trial Assessing the Repeatability and Tumor Uptake of [68Ga] Ga-HER2 Single-Domain Antibody PET/CT in Patients with Breast Carcinoma
O Gondry, V Caveliers, C Xavier, L Raes, M Vanhoeij, G Verfaillie, ...
Journal of Nuclear Medicine 65 (2), 178-184, 2024
12024
VNB-mediated endosomal escape triggers robust gene silencing in human cell lines
JC Fraire, G Houthaeve, J Liu, L Raes, S Stremersch, T Brans, ...
Colloidal Nanoparticles for Biomedical Applications XV 11255, 1125504, 2020
12020
Towards safe and efficient delivery of mRNA and CRISPR-Cas9 complexes in T cells by vapor nanobubble photoporation
L Raes, S Stremersch, J Fraire, T Brans, G Goetgeluk, J Van Hoeck, ...
HUMAN GENE THERAPY 30 (12), A13-A13, 2019
12019
Nanobody-based fluorescent contrast agents for rapid and specific intra-operative tumor visualization
S Hernot
Molecular-Guided Surgery: Molecules, Devices, and Applications X, PC128250N, 2024
2024
First in vivo results for a novel macroscale time-domain fluorescence imaging system
H Ingelberts, S Janssen, T Van Den Dries, T Lapauw, S Sahakian, ...
2023
A comparison of [68Ga] Ga-NOTA-anti-HER2-sdAb PET/CT with [18F] FDG-PET/CT in breast carcinoma patients.
O Gondry, C Xavier, J Heemskerk, LAJ Raes, J Debacker, F De Geeter, ...
18th Annual Meeting of the European Molecular Imaging (EMIM 2023), 2023
2023
Repeatability of 68GaNOTA-anti-HER2 sdAb in 20 breast cancer patients.
O Gondry, C Xavier, F De Geeter, K Glorieus, S Aspeslagh, S Joris, ...
EMIM 2022: 17th European Molecular Imaging Meeting, 2022
2022
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