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Timothy Cloughesy
Timothy Cloughesy
Geverifieerd e-mailadres voor mednet.ucla.edu
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Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
PY Wen, DR Macdonald, DA Reardon, TF Cloughesy, AG Sorensen, ...
Journal of clinical oncology 28 (11), 1963-1972, 2010
39792010
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
HS Friedman, MD Prados, PY Wen, T Mikkelsen, D Schiff, LE Abrey, ...
Journal of clinical oncology 27 (28), 4733-4740, 2009
29182009
Bevacizumab plus radiotherapy–temozolomide for newly diagnosed glioblastoma
OL Chinot, W Wick, W Mason, R Henriksson, F Saran, R Nishikawa, ...
New England Journal of Medicine 370 (8), 709-722, 2014
26272014
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
17172005
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12322007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11572007
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma
TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ...
Nature medicine 25 (3), 477-486, 2019
10732019
Gene expression profiling of gliomas strongly predicts survival
WA Freije, FE Castro-Vargas, Z Fang, S Horvath, T Cloughesy, LM Liau, ...
Cancer research 64 (18), 6503-6510, 2004
8822004
Standards of care for treatment of recurrent glioblastoma—are we there yet?
M Weller, T Cloughesy, JR Perry, W Wick
Neuro-oncology 15 (1), 4-27, 2013
8012013
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
S Horvath, B Zhang, M Carlson, KV Lu, S Zhu, RM Felciano, MF Laurance, ...
Proceedings of the National Academy of Sciences 103 (46), 17402-17407, 2006
7412006
Adult glioblastoma
BM Alexander, TF Cloughesy
Journal of Clinical Oncology 35 (21), 2402-2409, 2017
7372017
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ...
Neuro-oncology 22 (8), 1073-1113, 2020
6732020
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
TF Cloughesy, K Yoshimoto, P Nghiemphu, K Brown, J Dang, S Zhu, ...
PLoS medicine 5 (1), e8, 2008
6622008
Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials
BM Ellingson, M Bendszus, J Boxerman, D Barboriak, BJ Erickson, ...
Neuro-oncology 17 (9), 1188-1198, 2015
6372015
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
LM Liau, RM Prins, SM Kiertscher, SK Odesa, TJ Kremen, AJ Giovannone, ...
Clinical Cancer Research 11 (15), 5515-5525, 2005
6202005
Glioblastoma: from molecular pathology to targeted treatment
TF Cloughesy, WK Cavenee, PS Mischel
Annual review of pathology: mechanisms of disease 9, 1-25, 2014
5862014
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
DA Reardon, KL Fink, T Mikkelsen, TF Cloughesy, A O'Neill, S Plotkin, ...
Journal of clinical oncology 26 (34), 5610-5617, 2008
5812008
Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo
G Choe, S Horvath, TF Cloughesy, K Crosby, D Seligson, A Palotie, ...
Cancer research 63 (11), 2742-2746, 2003
5682003
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA
DA Nathanson, B Gini, J Mottahedeh, K Visnyei, T Koga, G Gomez, ...
Science 343 (6166), 72-76, 2014
5632014
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
A Lai, A Tran, PL Nghiemphu, WB Pope, OE Solis, M Selch, E Filka, ...
Journal of clinical oncology 29 (2), 142, 2011
5582011
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