| Impaired TFEB-mediated lysosome biogenesis and autophagy promote chronic ethanol-induced liver injury and steatosis in mice X Chao, S Wang, K Zhao, Y Li, JA Williams, T Li, H Chavan, ... Gastroenterology 155 (3), 865-879. e12, 2018 | 277 | 2018 |
| Cancer-associated fibroblasts drive glycolysis in a targetable signaling loop implicated in head and neck squamous cell carcinoma progression D Kumar, J New, V Vishwakarma, R Joshi, J Enders, F Lin, S Dasari, ... Cancer research 78 (14), 3769-3782, 2018 | 115 | 2018 |
| Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice H Wang, HM Ni, X Chao, X Ma, YA Rodriguez, H Chavan, S Wang, ... Redox biology 22, 101148, 2019 | 105 | 2019 |
| Editor’s highlight: metformin protects against acetaminophen hepatotoxicity by attenuation of mitochondrial oxidant stress and dysfunction K Du, A Ramachandran, JL Weemhoff, H Chavan, Y Xie, P Krishnamurthy, ... Toxicological Sciences 154 (2), 214-226, 2016 | 70 | 2016 |
| The ATP-binding cassette transporter ABCB6 is induced by arsenic and protects against arsenic cytotoxicity H Chavan, M Oruganti, P Krishnamurthy Toxicological Sciences 120 (2), 519-528, 2011 | 59 | 2011 |
| Dual role of epidermal growth factor receptor in liver injury and regeneration after acetaminophen overdose in mice B Bhushan, H Chavan, P Borude, Y Xie, K Du, MR McGill, M Lebofsky, ... Toxicological Sciences 155 (2), 363-378, 2017 | 56 | 2017 |
| Metabolomics reveals the formation of aldehydes and iminium in gefitinib metabolism X Liu, Y Lu, X Guan, B Dong, H Chavan, J Wang, Y Zhang, ... Biochemical pharmacology 97 (1), 111-121, 2015 | 50 | 2015 |
| Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription RP Kumar, S Ray, P Home, B Saha, B Bhattacharya, HM Wilkins, ... Development 145 (19), dev162644, 2018 | 48 | 2018 |
| Efficient purification and reconstitution of ATP binding cassette transporter B6 (ABCB6) for functional and structural studies H Chavan, MMT Khan, G Tegos, P Krishnamurthy Journal of Biological Chemistry 288 (31), 22658-22669, 2013 | 48 | 2013 |
| Targeting the enterohepatic bile acid signaling induces hepatic autophagy via a CYP7A1 - AKT - mTOR axis in mice Y Wang, Y Ding, J Li, H Chavan, D Matye, HM Ni, JYL Chiang, ... Cellular and Molecular Gastroenterology and Hepatology, 2016 | 46 | 2016 |
| Sortilin 1 modulates hepatic cholesterol lipotoxicity in mice via functional interaction with liver carboxylesterase 1 J Li, Y Wang, DJ Matye, H Chavan, P Krishnamurthy, F Li, T Li Journal of Biological Chemistry 292 (1), 146-160, 2017 | 42 | 2017 |
| Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma K Polireddy, H Chavan, BA Abdulkarim, P Krishnamurthy Molecular oncology 5 (5), 410-425, 2011 | 42 | 2011 |
| Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR) H Chavan, P Krishnamurthy Journal of Biological Chemistry 287 (38), 32054-32068, 2012 | 34 | 2012 |
| Lack of toxicity in non-human primates receiving clinically relevant doses of an AAV9. U7snRNA vector designed to induce DMD exon 2 skipping LV Gushchina, EC Frair, NL Rohan, AJ Bradley, HD Chavan, HJ Chou, ... Human Gene Therapy, 2021 | 31 | 2021 |
| Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer C Li, C He, Y Xu, H Xu, Y Tang, H Chavan, S Duan, A Artigues, ML Forrest, ... The Prostate 79 (6), 628-639, 2019 | 31 | 2019 |
| Arsenite effects on mitochondrial bioenergetics in human and mouse primary hepatocytes follow a nonlinear dose response H Chavan, P Christudoss, K Mickey, R Tessman, H Ni, R Swerdlow, ... Oxidative Medicine and Cellular Longevity 2017, 2017 | 29 | 2017 |
| A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6 K Polireddy, MMT Khan, H Chavan, S Young, X Ma, A Waller, M Garcia, ... PLoS One 7 (7), e40005, 2012 | 23 | 2012 |
| Proteomic analysis of miltefosine-resistant Leishmania reveals the possible involvement of eukaryotic initiation factor 4A (eIF4A) G Singh, HD Chavan, CS Dey International journal of antimicrobial agents 31 (6), 584-586, 2008 | 22 | 2008 |
| Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver H Chavan, F Li, R Tessman, K Mickey, K Dorko, T Schmitt, S Kumer, ... Journal of Biological Chemistry 290 (12), 7871-7886, 2015 | 18 | 2015 |
| Proteomic analysis of wild type and arsenite-resistant Leishmania donovani S Sharma, G Singh, HD Chavan, CS Dey Experimental parasitology 123 (4), 369-376, 2009 | 18 | 2009 |
Wen-Xing DingUniversity of Kansas Medical CenterVerified email at kumc.edu
