Menno de Winther
Menno de Winther
Professor of Vascular Immune Cell Biology
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Nuclear factor κB signaling in atherogenesis
MPJ De Winther, E Kanters, G Kraal, MH Hofker
Arteriosclerosis, thrombosis, and vascular biology 25 (5), 904-914, 2005
Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo
N Jetten, S Verbruggen, MJ Gijbels, MJ Post, MPJ De Winther, ...
Angiogenesis 17 (1), 109-118, 2014
Distribution of macrophage polarization markers in human atherosclerosis
JL Stöger, MJJ Gijbels, S van der Velden, M Manca, CM van der Loos, ...
Atherosclerosis 225 (2), 461-468, 2012
Myeloperoxidase: molecular mechanisms of action and their relevance to human health and disease
BS Van der Veen, MPJ de Winther, P Heeringa
Antioxidants & redox signaling 11 (11), 2899-2937, 2009
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
J Van den Bossche, J Baardman, NA Otto, S van der Velden, AE Neele, ...
Cell reports 17 (3), 684-696, 2016
Endothelial cell-specific NF-κB inhibition protects mice from atherosclerosis
R Gareus, E Kotsaki, S Xanthoulea, I van der Made, MJJ Gijbels, ...
Cell metabolism 8 (5), 372-383, 2008
Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice
E Kanters, M Pasparakis, MJJ Gijbels, MN Vergouwe, I Partouns-Hendriks, ...
The Journal of clinical investigation 112 (8), 1176-1185, 2003
Macrophage scavenger receptor class A: a multifunctional receptor in atherosclerosis
MPJ de Winther, KW van Dijk, LM Havekes, MH Hofker
Arteriosclerosis, thrombosis, and vascular biology 20 (2), 290-297, 2000
Atherosclerotic plaque destabilization: mechanisms, models, and therapeutic strategies
C Silvestre-Roig, MP De Winther, C Weber, MJ Daemen, E Lutgens, ...
Circulation research 114 (1), 214-226, 2014
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
E Lutgens, D Lievens, L Beckers, E Wijnands, O Soehnlein, A Zernecke, ...
Journal of Experimental Medicine 207 (2), 391-404, 2010
Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice
JJ Manning-Tobin, KJ Moore, TA Seimon, SA Bell, M Sharuk, ...
Arteriosclerosis, thrombosis, and vascular biology 29 (1), 19-26, 2009
Disruption of the Cathepsin K Gene Reduces Atherosclerosis Progression and Induces Plaque Fibrosis but Accelerates Macrophage Foam Cell Formation
E Lutgens, SPM Lutgens, BCG Faber, S Heeneman, MMJ Gijbels, ...
Circulation 113 (1), 98-107, 2006
Macrophage microRNA-155 promotes cardiac hypertrophy and failure
S Heymans, MF Corsten, W Verhesen, P Carai, REW Van Leeuwen, ...
Circulation 128 (13), 1420-1432, 2013
Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation
IMJ Wolfs, MMPC Donners, MPJ de Winther
Thrombosis and haemostasis 106 (11), 763-771, 2011
Accumulation of Myeloperoxidase-Positive Neutrophils in Atherosclerotic Lesions in LDLR−/− Mice
M Van Leeuwen, MJJ Gijbels, A Duijvestijn, M Smook, MJ van de Gaar, ...
Arteriosclerosis, thrombosis, and vascular biology 28 (1), 84-89, 2008
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions
P Goossens, MJJ Gijbels, A Zernecke, W Eijgelaar, MN Vergouwe, ...
Cell metabolism 12 (2), 142-153, 2010
MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis
MF Corsten, A Papageorgiou, W Verhesen, P Carai, M Lindow, S Obad, ...
Circulation research 111 (4), 415-425, 2012
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis
J Van den Bossche, J Baardman, MPJ de Winther
JoVE (Journal of Visualized Experiments), e53424, 2015
The Class A Macrophage Scavenger Receptor Is a Major Pattern Recognition Receptor for Neisseria meningitidis Which Is Independent of Lipopolysaccharide and …
L Peiser, MPJ De Winther, K Makepeace, M Hollinshead, P Coull, ...
Infection and immunity 70 (10), 5346-5354, 2002
Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice
V Bieghs, K Wouters, PJ Van Gorp, MJJ Gijbels, MPJ De Winther, ...
Gastroenterology 138 (7), 2477-2486. e3, 2010
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