|High frequency of mutations of the PIK3CA gene in human cancers|
Y Samuels, Z Wang, A Bardelli, N Silliman, J Ptak, S Szabo, H Yan, ...
Science 304 (5670), 554-554, 2004
|Genomic classification of cutaneous melanoma|
R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ...
Cell 161 (7), 1681-1696, 2015
|Mutant PIK3CA promotes cell growth and invasion of human cancer cells|
Y Samuels, LA Diaz Jr, O Schmidt-Kittler, JM Cummins, L DeLong, ...
Cancer cell 7 (6), 561-573, 2005
|Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells|
PF Robbins, YC Lu, M El-Gamil, YF Li, C Gross, J Gartner, JC Lin, JK Teer, ...
Nature medicine 19 (6), 747, 2013
|ASPP proteins specifically stimulate the apoptotic function of p53|
Y Samuels-Lev, DJ O'Connor, D Bergamaschi, G Trigiante, JK Hsieh, ...
Molecular cell 8 (4), 781-794, 2001
|The PIK3CA gene is mutated with high frequency in human breast cancers|
KE Bachman, P Argani, Y Samuels, N Silliman, J Ptak, S Szabo, ...
Cancer biology & therapy 3 (8), 772-775, 2004
|Colorectal cancer: mutations in a signalling pathway|
DW Parsons, TL Wang, Y Samuels, A Bardelli, JM Cummins, L DeLong, ...
Nature 436 (7052), 792, 2005
|Oncogenic PI3K and its role in cancer|
Y Samuels, K Ericson
Current opinion in oncology 18 (1), 77-82, 2006
|The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations|
CH Huang, D Mandelker, O Schmidt-Kittler, Y Samuels, VE Velculescu, ...
Science 318 (5857), 1744-1748, 2007
|Exome sequencing identifies GRIN2A as frequently mutated in melanoma|
X Wei, V Walia, JC Lin, JK Teer, TD Prickett, J Gartner, S Davis, ...
Nature genetics 43 (5), 442, 2011
|Oncogenic mutations of PIK3CA in human cancers|
Y Samuels, VE Velculescu
Cell cycle 3 (10), 1221-1224, 2004
|iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human|
D Bergamaschi, Y Samuels, NJ O'Neil, G Trigiante, T Crook, JK Hsieh, ...
Nature genetics 33 (2), 162, 2003
|Mutational inactivation of STAG2 causes aneuploidy in human cancer|
DA Solomon, T Kim, LA Diaz-Martinez, J Fair, AG Elkahloun, BT Harris, ...
Science 333 (6045), 1039-1043, 2011
|Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas|
DK Broderick, C Di, TJ Parrett, YR Samuels, JM Cummins, RE McLendon, ...
Cancer research 64 (15), 5048-5050, 2004
|Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4|
TD Prickett, NS Agrawal, X Wei, KE Yates, JC Lin, JR Wunderlich, ...
Nature genetics 41 (10), 1127, 2009
|Efficient identification of mutated cancer antigens recognized by T cells associated with durable tumor regressions|
YC Lu, X Yao, JS Crystal, YF Li, M El-Gamil, C Gross, L Davis, ME Dudley, ...
Clinical Cancer Research 20 (13), 3401-3410, 2014
|ASPP1 and ASPP2: common activators of p53 family members|
D Bergamaschi, Y Samuels, B Jin, S Duraisingham, T Crook, X Lu
Molecular and cellular biology 24 (3), 1341-1350, 2004
|iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53|
D Bergamaschi, Y Samuels, A Sullivan, M Zvelebil, H Breyssens, A Bisso, ...
Nature genetics 38 (10), 1133, 2006
|Analysis of the genome to personalize therapy for melanoma|
MA Davies, Y Samuels
Oncogene 29 (41), 5545, 2010
|Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion|
K Tateishi, H Wakimoto, AJ Iafrate, S Tanaka, F Loebel, N Lelic, ...
Cancer cell 28 (6), 773-784, 2015