High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae J Wong, T de Rond, L d’Espaux, C van der Horst, I Dev, L Rios-Solis, ... Metabolic engineering 45, 142-148, 2018 | 63 | 2018 |
Structural basis of selective cannabinoid CB2 receptor activation X Li, H Chang, J Bouma, LV de Paus, P Mukhopadhyay, J Paloczi, ... Nature Communications 14 (1), 1447, 2023 | 40 | 2023 |
De novo synthesis of the sedative valerenic acid in Saccharomyces cerevisiae J Wong, L d’Espaux, I Dev, C van der Horst, J Keasling Metabolic engineering 47, 94-101, 2018 | 29 | 2018 |
Design and characterization of an intracellular covalent ligand for CC chemokine receptor 2 NV Ortiz Zacarías, KK Chahal, T Šimková, C Van Der Horst, Y Zheng, ... Journal of Medicinal Chemistry 64 (5), 2608-2621, 2021 | 18 | 2021 |
Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists M Patberg, A Isaak, F Füsser, NVO Zacarías, L Vinnenberg, J Schulte, ... European Journal of Medicinal Chemistry 226, 113838, 2021 | 9 | 2021 |
A multiple classifier system identifies novel cannabinoid CB2 receptor ligands D Ruano-Ordás, L Burggraaff, R Liu, C van der Horst, LH Heitman, ... Journal of Cheminformatics 11, 1-14, 2019 | 5 | 2019 |
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R) L Mach, A Omran, J Bouma, S Radetzki, DA Sykes, W Guba, X Li, ... Journal of Medicinal Chemistry 67 (14), 11841-11867, 2024 | 2 | 2024 |
SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism G Wágner, TAM Mocking, X Ma, I Slynko, D Da Costa Pereira, ... Archiv der Pharmazie 356 (1), 2200451, 2023 | 2 | 2023 |
Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor J Bouma, JD Broekhuis, C van der Horst, P Kumar, A Ligresti, ... Biochemical Pharmacology 218, 115924, 2023 | 1 | 2023 |
Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe LS den Hollander, BLH Beerkens, S Dekkers, JPD van Veldhoven, ... ACS Chemical Biology 19 (9), 2070-2080, 2024 | | 2024 |
Visualization of membrane localization and the functional state of CB 2 R pools using matched agonist and inverse agonist probe pairs M Wąsińska-Kałwa, A Omran, L Mach, L Scipioni, J Bouma, X Li, ... Chemical Science, 2024 | | 2024 |
The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles VM Straub, B Barti, ST Tandar, AF Stevens, T van der Wel, N Zhu, ... bioRxiv, 2024.09. 23.614520, 2024 | | 2024 |