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Cas van der Horst
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High-titer production of lathyrane diterpenoids from sugar by engineered Saccharomyces cerevisiae
J Wong, T de Rond, L d’Espaux, C van der Horst, I Dev, L Rios-Solis, ...
Metabolic engineering 45, 142-148, 2018
632018
Structural basis of selective cannabinoid CB2 receptor activation
X Li, H Chang, J Bouma, LV de Paus, P Mukhopadhyay, J Paloczi, ...
Nature Communications 14 (1), 1447, 2023
402023
De novo synthesis of the sedative valerenic acid in Saccharomyces cerevisiae
J Wong, L d’Espaux, I Dev, C van der Horst, J Keasling
Metabolic engineering 47, 94-101, 2018
292018
Design and characterization of an intracellular covalent ligand for CC chemokine receptor 2
NV Ortiz Zacarías, KK Chahal, T Šimková, C Van Der Horst, Y Zheng, ...
Journal of Medicinal Chemistry 64 (5), 2608-2621, 2021
182021
Piperazine squaric acid diamides, a novel class of allosteric P2X7 receptor antagonists
M Patberg, A Isaak, F Füsser, NVO Zacarías, L Vinnenberg, J Schulte, ...
European Journal of Medicinal Chemistry 226, 113838, 2021
92021
A multiple classifier system identifies novel cannabinoid CB2 receptor ligands
D Ruano-Ordás, L Burggraaff, R Liu, C van der Horst, LH Heitman, ...
Journal of Cheminformatics 11, 1-14, 2019
52019
Highly Selective Drug-Derived Fluorescent Probes for the Cannabinoid Receptor Type 1 (CB1R)
L Mach, A Omran, J Bouma, S Radetzki, DA Sykes, W Guba, X Li, ...
Journal of Medicinal Chemistry 67 (14), 11841-11867, 2024
22024
SAR exploration of the non‐imidazole histamine H3 receptor ligand ZEL‐H16 reveals potent inverse agonism
G Wágner, TAM Mocking, X Ma, I Slynko, D Da Costa Pereira, ...
Archiv der Pharmazie 356 (1), 2200451, 2023
22023
Dual allosteric and orthosteric pharmacology of synthetic analog cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor
J Bouma, JD Broekhuis, C van der Horst, P Kumar, A Ligresti, ...
Biochemical Pharmacology 218, 115924, 2023
12023
Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe
LS den Hollander, BLH Beerkens, S Dekkers, JPD van Veldhoven, ...
ACS Chemical Biology 19 (9), 2070-2080, 2024
2024
Visualization of membrane localization and the functional state of CB 2 R pools using matched agonist and inverse agonist probe pairs
M Wąsińska-Kałwa, A Omran, L Mach, L Scipioni, J Bouma, X Li, ...
Chemical Science, 2024
2024
The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles
VM Straub, B Barti, ST Tandar, AF Stevens, T van der Wel, N Zhu, ...
bioRxiv, 2024.09. 23.614520, 2024
2024
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Artikelen 1–12