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Chung-ke Chang
Chung-ke Chang
Geverifieerd e-mailadres voor ibms.sinica.edu.tw
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The SARS coronavirus nucleocapsid protein–forms and functions
C Chang, MH Hou, CF Chang, CD Hsiao, T Huang
Antiviral research 103, 39-50, 2014
5342014
Modular organization of SARS coronavirus nucleocapsid protein
C Chang, SC Sue, T Yu, CM Hsieh, CK Tsai, YC Chiang, S Lee, H Hsiao, ...
Journal of biomedical science 13, 59-72, 2006
3972006
Structure of the SARS coronavirus nucleocapsid protein RNA-binding dimerization domain suggests a mechanism for helical packaging of viral RNA
CY Chen, C Chang, YW Chang, SC Sue, HI Bai, L Riang, CD Hsiao, ...
Journal of molecular biology 368 (4), 1075-1086, 2007
2752007
Assembly of severe acute respiratory syndrome coronavirus RNA packaging signal into virus-like particles is nucleocapsid dependent
PK Hsieh, SC Chang, CC Huang, TT Lee, CW Hsiao, YH Kou, IY Chen, ...
Journal of virology 79 (22), 13848-13855, 2005
2362005
Multiple nucleic acid binding sites and intrinsic disorder of severe acute respiratory syndrome coronavirus nucleocapsid protein: implications for ribonucleocapsid protein …
CK Chang, YL Hsu, YH Chang, FA Chao, MC Wu, YS Huang, CK Hu, ...
Journal of virology 83 (5), 2255-2264, 2009
1932009
Recent insights into the development of therapeutics against coronavirus diseases by targeting N protein
C Chang, SC Lo, YS Wang, MH Hou
Drug discovery today 21 (4), 562-572, 2016
1252016
Solution structure of the c-terminal dimerization domain of SARS coronavirus nucleocapsid protein solved by the SAIL-NMR method
M Takeda, C Chang, T Ikeya, P Güntert, Y Chang, Y Hsu, T Huang, ...
Journal of molecular biology 380 (4), 608-622, 2008
1232008
Transient oligomerization of the SARS-CoV N protein–implication for virus ribonucleoprotein packaging
C Chang, CMM Chen, M Chiang, Y Hsu, T Huang
PloS one 8 (5), e65045, 2013
1192013
The N-terminus of TDP-43 promotes its oligomerization and enhances DNA binding affinity
C Chang, TH Wu, CY Wu, M Chiang, EKW Toh, YC Hsu, KF Lin, Y Liao, ...
Biochemical and biophysical research communications 425 (2), 219-224, 2012
1182012
Structure-based stabilization of non-native protein–protein interactions of coronavirus nucleocapsid proteins in antiviral drug design
SM Lin, SC Lin, JN Hsu, C Chang, CM Chien, YS Wang, HY Wu, US Jeng, ...
Journal of medicinal chemistry 63 (6), 3131-3141, 2020
1092020
Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function
C Chang, M Chiang, EKW Toh, CF Chang, T Huang
FEBS letters 587 (6), 575-582, 2013
762013
The dimer interface of the SARS coronavirus nucleocapsid protein adapts a porcine respiratory and reproductive syndrome virus-like structure
C Chang, SC Sue, T Yu, CM Hsieh, CK Tsai, YC Chiang, S Lee, H Hsiao, ...
FEBS letters 579 (25), 5663-5668, 2005
612005
Structure-based virtual screening and experimental validation of the discovery of inhibitors targeted towards the human coronavirus nucleocapsid protein
C Chang, S Jeyachandran, NJ Hu, CL Liu, SY Lin, YS Wang, YM Chang, ...
Molecular biosystems 12 (1), 59-66, 2016
562016
Effects of Amino Acid Substitutions at β131 on the Structure and Properties of Hemoglobin:  Evidence for Communication between α1β1- and α1β2-Subunit …
C Chang, V Simplaceanu, C Ho
Biochemistry 41 (17), 5644-5655, 2002
412002
Parity-dependent hairpin configurations of repetitive DNA sequence promote slippage associated with DNA expansion
TY Huang, C Chang, YF Kao, CH Chin, CW Ni, HY Hsu, NJ Hu, LC Hsieh, ...
Proceedings of the National Academy of Sciences 114 (36), 9535-9540, 2017
342017
A survey of recent unusual high-resolution DNA structures provoked by mismatches, repeats and ligand binding
R Satange, C Chang, MH Hou
Nucleic acids research 46 (13), 6416-6434, 2018
332018
Targeting protein-protein interaction interfaces in COVID-19 drug discovery
C Chang, SM Lin, R Satange, SC Lin, SC Sun, HY Wu, K Kehn-Hall, ...
Computational and structural biotechnology journal 19, 2246-2255, 2021
312021
Induced‐Fit Recognition of CCG Trinucleotide Repeats by a Nickel–Chromomycin Complex Resulting in Large‐Scale DNA Deformation
WH Tseng, C Chang, PC Wu, NJ Hu, GH Lee, CC Tzeng, S Neidle, ...
Angewandte Chemie International Edition 56 (30), 8761-8765, 2017
312017
Structural dynamics of the two-component response regulator RstA in recognition of promoter DNA element
YC Li, C Chang, CF Chang, YH Cheng, PJ Fang, T Yu, SC Chen, YC Li, ...
Nucleic acids research 42 (13), 8777-8788, 2014
302014
Cooperative recognition of T: T mismatch by echinomycin causes structural distortions in DNA duplex
PC Wu, SL Tzeng, C Chang, YF Kao, MJ Waring, MH Hou
Nucleic acids research 46 (14), 7396-7404, 2018
232018
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Artikelen 1–20