Gautam Goel
Gautam Goel
ImmusanT
Verified email at immusant.com - Homepage
Title
Cited by
Cited by
Year
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ...
Nature 496 (7444), 238-242, 2013
17752013
Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages
EM Palsson-McDermott, AM Curtis, G Goel, MAR Lauterbach, FJ Sheedy, ...
Cell metabolism 21 (1), 65-80, 2015
5312015
Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon gamma
S Hwang, NS Maloney, MW Bruinsma, G Goel, E Duan, L Zhang, ...
Cell host & microbe 11 (4), 397-409, 2012
1942012
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection
KL Conway, P Kuballa, JH Song, KK Patel, AB Castoreno, OH Yilmaz, ...
Gastroenterology 145 (6), 1347-1357, 2013
1892013
Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis
M Beaudoin, P Goyette, G Boucher, KS Lo, MA Rivas, C Stevens, ...
PLoS Genet 9 (9), e1003723, 2013
1522013
Helminth infection reactivates latent γ-herpesvirus via cytokine competition at a viral promoter
TA Reese, BS Wakeman, HS Choi, MM Hufford, SC Huang, X Zhang, ...
Science 345 (6196), 573-577, 2014
1502014
Regulation of glycolysis in Lactococcus lactis: an unfinished systems biological case study
EO Voit, J Almeida, S Marino, R Lall, G Goel, AR Neves, H Santos
IEE Proceedings-Systems Biology 153 (4), 286-298, 2006
932006
System estimation from metabolic time-series data
G Goel, IC Chou, EO Voit
Bioinformatics 24 (21), 2505-2511, 2008
902008
Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies
G Goel, T King, AJ Daveson, JM Andrews, J Krishnarajah, R Krause, ...
The lancet Gastroenterology & hepatology 2 (7), 479-493, 2017
832017
Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAFV600E colorectal cancer
EM Coffee, AC Faber, J Roper, MJ Sinnamon, G Goel, L Keung, ...
Clinical cancer research 19 (10), 2688-2698, 2013
762013
Mechanisms of pediatric inflammatory bowel disease
JM Peloquin, G Goel, EJ Villablanca, RJ Xavier
Annual review of immunology 34, 31-64, 2016
642016
A systems biology viewpoint on autophagy in health and disease
A Huett, G Goel, RJ Xavier
Current opinion in gastroenterology 26 (4), 302-309, 2010
562010
Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk
KG Lassen, CI McKenzie, M Mari, T Murano, J Begun, LA Baxt, G Goel, ...
Immunity 44 (6), 1392-1405, 2016
552016
Biological systems modeling and analysis: a biomolecular technique of the twenty-first century
G Goel, IC Chou, EO Voit
Journal of biomolecular techniques: JBT 17 (4), 252, 2006
512006
Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules
SY Shaw, K Tran, AB Castoreno, JM Peloquin, KG Lassen, B Khor, ...
ACS chemical biology 8 (12), 2724-2733, 2013
502013
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics
SY Kuo, AB Castoreno, LN Aldrich, KG Lassen, G Goel, V Dančík, ...
Proceedings of the National Academy of Sciences 112 (31), E4281-E4287, 2015
472015
RNF166 determines recruitment of adaptor proteins during antibacterial autophagy
RJ Heath, G Goel, LA Baxt, JS Rush, V Mohanan, GLC Paulus, V Jani, ...
Cell reports 17 (9), 2183-2194, 2016
452016
Essential cell-autonomous role for interferon (IFN) regulatory factor 1 in IFN-γ-mediated inhibition of norovirus replication in macrophages
NS Maloney, LB Thackray, G Goel, S Hwang, E Duan, P Vachharajani, ...
Journal of virology 86 (23), 12655-12664, 2012
442012
p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation
KL Conway, G Goel, H Sokol, M Manocha, E Mizoguchi, C Terhorst, ...
The Journal of Immunology 189 (7), 3631-3640, 2012
442012
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells
B Khor, JD Gagnon, G Goel, MI Roche, KL Conway, K Tran, LN Aldrich, ...
Elife 4, e05920, 2015
352015
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