Janet Askari
Janet Askari
Geverifieerd e-mailadres voor manchester.ac.uk
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Linking integrin conformation to function
JA Askari, PA Buckley, AP Mould, MJ Humphries
Journal of cell science 122 (2), 165-170, 2009
3682009
Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly
ER Horton, A Byron, JA Askari, DHJ Ng, A Millon-Frémillon, J Robertson, ...
Nature cell biology 17 (12), 1577-1587, 2015
3372015
Integrin-specific signaling pathways controlling focal adhesion formation and cell migration
Z Mostafavi-Pour, JA Askari, SJ Parkinson, PJ Parker, TTC Ng, ...
Journal of Cell Biology 161 (1), 155-167, 2003
2612003
Crystal structure of a heparin‐and integrin‐binding segment of human fibronectin
A Sharma, JA Askari, MJ Humphries, EY Jones, DI Stuart
The EMBO Journal 18 (6), 1468-1479, 1999
2271999
SHARPIN is an endogenous inhibitor of β1-integrin activation
JK Rantala, J Pouwels, T Pellinen, S Veltel, P Laasola, E Mattila, ...
Nature cell biology 13 (11), 1315-1324, 2011
2062011
Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies EVIDENCE THAT THE SYNERGY SEQUENCE OF FIBRONECTIN IS …
AP Mould, JA Askari, S Aota, KM Yamada, A Irie, Y Takada, HJ Mardon, ...
Journal of Biological Chemistry 272 (28), 17283-17292, 1997
2061997
Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies EVIDENCE THAT THE SYNERGY SEQUENCE OF FIBRONECTIN IS …
AP Mould, JA Askari, S Aota, KM Yamada, A Irie, Y Takada, HJ Mardon, ...
Journal of Biological Chemistry 272 (28), 17283-17292, 1997
2061997
Anti-integrin monoclonal antibodies
A Byron, JD Humphries, JA Askari, SE Craig, AP Mould, MJ Humphries
Journal of cell science 122 (22), 4009-4011, 2009
1812009
Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit
AP Mould, AN Garratt, JA Askari, SK Akiyama, MJ Humphries
FEBS letters 363 (1-2), 118-122, 1995
1781995
Integrin alpha 4 beta 1-mediated melanoma cell adhesion and migration on vascular cell adhesion molecule-1 (VCAM-1) and the alternatively spliced IIICS region of fibronectin.
AP Mould, JA Askari, SE Craig, AN Garratt, J Clements, MJ Humphries
Journal of Biological Chemistry 269 (44), 27224-27230, 1994
1611994
Conformational Changes in the Integrin औA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement
AP Mould, SJ Barton, JA Askari, PA McEwan, PA Buckley, SE Craig, ...
Journal of Biological Chemistry 278 (19), 17028-17035, 2003
1532003
Integrin activation involves a conformational change in the α1 helix of the β subunit A-domain
AP Mould, JA Askari, S Barton, AD Kline, PA McEwan, SE Craig, ...
Journal of Biological Chemistry 277 (22), 19800-19805, 2002
1512002
Signal transduction via integrin adhesion complexes
JD Humphries, MR Chastney, JA Askari, MJ Humphries
Current opinion in cell biology 56, 14-21, 2019
1352019
The integrin adhesome network at a glance
ER Horton, JD Humphries, J James, MC Jones, JA Askari, MJ Humphries
Journal of cell science 129 (22), 4159-4163, 2016
1352016
Molecular basis of ligand recognition by integrin α5β1: I. Specificity of ligand binding is determined by amino acid sequences in the second and third NH2-terminal repeats of …
AP Mould, JA Askari, MJ Humphries
Journal of Biological Chemistry 275 (27), 20324-20336, 2000
1352000
A specific α5β1-integrin conformation promotes directional integrin translocation and fibronectin matrix formation
K Clark, R Pankov, MA Travis, JA Askari, AP Mould, SE Craig, P Newham, ...
Journal of cell science 118 (2), 291-300, 2005
1312005
Focal adhesions are sites of integrin extension
JA Askari, CJ Tynan, SED Webb, ML Martin-Fernandez, C Ballestrem, ...
Journal of Cell Biology 188 (6), 891-903, 2010
1212010
Role of ADMIDAS cation-binding site in ligand recognition by integrin α5β1
AP Mould, SJ Barton, JA Askari, SE Craig, MJ Humphries
Journal of Biological Chemistry 278 (51), 51622-51629, 2003
1162003
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis
AP Mould, EJH Symonds, PA Buckley, JG Grossmann, PA McEwan, ...
Journal of Biological Chemistry 278 (41), 39993-39999, 2003
1162003
Competitive binding of vascular cell adhesion molecule-1 and the HepII/IIICS domain of fibronectin to the integrin alpha 4 beta 1.
R Makarem, P Newham, JA Askari, LJ Green, J Clements, M Edwards, ...
Journal of Biological Chemistry 269 (6), 4005-4011, 1994
1151994
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