Coen Maas, PhD
Coen Maas, PhD
Associate Professor, Department of Clinical Chemistry and Haematology, University Medical Center
Verified email at
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In vivo roles of factor XII
T RennÚ, AH Schmaier, KF Nickel, M Blombńck, C Maas
Blood 120 (22), 4296, 2012
Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation
C Maas, JWP Govers-Riemslag, B Bouma, B Schiks, BPC Hazenberg, ...
The Journal of clinical investigation 118 (9), 3208, 2008
Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo
C Oschatz, C Maas, B Lecher, T Jansen, J Bj÷rkqvist, T Tradler, ...
Immunity 34 (2), 258-268, 2011
Antibody response to aggregated human interferon alpha2b in wild‐type and transgenic immune tolerant mice depends on type and level of aggregation
S Hermeling, H Schellekens, C Maas, MFBG Gebbink, DJA Crommelin, ...
Journal of pharmaceutical sciences 95 (5), 1084-1096, 2006
A role for protein misfolding in immunogenicity of biopharmaceuticals
C Maas, S Hermeling, B Bouma, W Jiskoot, MFBG Gebbink
Journal of Biological Chemistry 282 (4), 2229, 2007
Defective glycosylation of coagulation factor XII underlies hereditary angioedema type III
J Bj÷rkqvist, S de Maat, U Lewandrowski, A Di Gennaro, C Oschatz, ...
The Journal of clinical investigation 125 (8), 3132-3146, 2015
Coagulation factor XII in thrombosis and inflammation
C Maas, T RennÚ
Blood, The Journal of the American Society of Hematology 131 (17), 1903-1909, 2018
Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations
S de Maat, J Bj÷rkqvist, C Suffritti, CP Wiesenekker, W Nagtegaal, ...
Journal of Allergy and Clinical Immunology 138 (5), 1414-1423. e9, 2016
Plasma contact system activation drives anaphylaxis in severe mast cell–mediated allergic reactions
A Sala-Cunill, J Bj÷rkqvist, R Senter, M Guilarte, V Cardona, M Labrador, ...
Journal of Allergy and Clinical Immunology 135 (4), 1031-1043. e6, 2015
The plasma contact system 2.0
C Maas, C Oschatz, T RennÚ
Seminars in thrombosis and hemostasis 37 (04), 375-381, 2011
Polyphosphate nanoparticles on the platelet surface trigger contact system activation
JJF Verhoef, AD Barendrecht, KF Nickel, K Dijkxhoorn, E Kenne, ...
Blood, The Journal of the American Society of Hematology 129 (12), 1707-1717, 2017
Immune responses against domain I of β2‐glycoprotein I are driven by conformational changes
B de Laat, M van Berkel, RT Urbanus, B Siregar, P de Groot, M Gebbink, ...
Arthritis & Rheumatism 63 (12), 3960-8, 2011
Bradykinin: inflammatory product of the coagulation system
Z Hofman, S de Maat, CE Hack, C Maas
Clinical reviews in allergy & immunology 51, 152-161, 2016
PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells
E Steller, D Raats, J Koster, B Rutten, K Govaert, B Emmink, N Snoeren, ...
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy
C Tersteeg, S de Maat, SF De Meyer, MWJ Smeets, AD Barendrecht, ...
Circulation 129 (12), 1320-1331, 2014
SERPINs—from trap to treatment
W Sanrattana, C Maas, S De Maat
Frontiers in medicine 6, 25, 2019
New insights into the role of erythrocytes in thrombus formation
VX Du, D Huskens, C Maas, R Al Dieri, PG de Groot, B de Laat
Seminars in thrombosis and hemostasis 40 (01), 072-080, 2014
Factor XII: form determines function
S De Maat, C Maas
Journal of Thrombosis and Haemostasis 14 (8), 1498-1506, 2016
Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection
L Labberton, E Kenne, AT Long, KF Nickel, A Di Gennaro, RA Rigg, ...
Nature communications 7 (1), 12616, 2016
Physiological responses to protein aggregates: fibrinolysis, coagulation and inflammation (new roles for old factors)
MFBG Gebbink, B Bouma, C Maas, BN Bouma
FEBS letters 583 (16), 2691-2699, 2009
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