Shenghui He
Shenghui He
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Increasing p16 INK4a expression decreases forebrain progenitors and neurogenesis during ageing
AV Molofsky, SG Slutsky, NM Joseph, S He, R Pardal, J Krishnamurthy, ...
Nature 443 (7110), 448-452, 2006
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
AV Molofsky, S He, M Bydon, SJ Morrison, R Pardal
Genes & development 19 (12), 1432-1437, 2005
Mechanisms of stem cell self-renewal
HE Shenghui, D Nakada, SJ Morrison
Annual Review of Cell and Developmental 25, 377-406, 2009
Senescence in health and disease
S He, NE Sharpless
Cell 169 (6), 1000-1011, 2017
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU
MJ Kiel, S He, R Ashkenazi, SN Gentry, M Teta, JA Kushner, TL Jackson, ...
Nature 449 (7159), 238-242, 2007
Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors
I Kim, S He, OH Yilmaz, MJ Kiel, SJ Morrison
Blood 108 (2), 737-744, 2006
Enteric glia are multipotent in culture but primarily form glia in the adult rodent gut
NM Joseph, S He, E Quintana, YG Kim, G Nez, SJ Morrison
The Journal of clinical investigation 121 (9), 3398-3411, 2011
Stem cell self-renewal and cancer cell proliferation are regulated by common networks that balance the activation of proto-oncogenes and tumor suppressors
R Pardal, AV Molofsky, S He, SJ Morrison
Cold Spring Harbor symposia on quantitative biology 70, 177-185, 2005
Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors
S He, I Kim, MS Lim, SJ Morrison
Genes & development 25 (15), 1613-1627, 2011
Bmi-1 over-expression in neural stem/progenitor cells increases proliferation and neurogenesis in culture but has little effect on these functions in vivo
S He, T Iwashita, J Buchstaller, AV Molofsky, D Thomas, SJ Morrison
Developmental biology 328 (2), 257-272, 2009
Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion
S He, PJ Roberts, JA Sorrentino, JE Bisi, H Storrie-White, RG Tiessen, ...
Science translational medicine 9 (387), 2017
The first human trial of CRISPR-based cell therapy clears safety concerns as new treatment for late-stage lung cancer
S He
Signal Transduction and Targeted Therapy 5 (1), 1-2, 2020
The impact of aging on cancer progression and treatment
S He, NE Sharpless
Advances in Geroscience, 53-83, 2016
G1T28-1, a novel CDK4/6 inhibitor, protects murine hematopoietic stem and progenitor cells from cytotoxic chemotherapy
JA Sorrentino, S He, JE Bisi, PJ Roberts, JC Strum, NE Sharpless
Cancer Research 75 (15 Supplement), 941-941, 2015
G1T28, a CDK4/6 inhibitor, preserves T lymphocyte function from damage by cytotoxic chemotherapy
P Roberts, S He, G Schvartsman, T Patil, J Sorrentio, J Bisi, R Hoyer, ...
European Journal of Cancer 1 (69), S143-S144, 2016
Stem cell self-renewal and aging reflect a balance between repression and age-related activation of the INK4A and ARF senescence pathways.
R Pardal, AV Molofsky, SH He, GM Kruger, SJ Morrison
Developmental Biology 283 (2), 582-582, 2005
Transcriptional regulation of stem cell self-renewal
S He
University of Michigan, 2010
Bmil promotes adult stem cell self-renewal by repressing the expression of senescence pathways
A Molofsky, R Pardal, SH He, S Morrison
Differentiation 72 (6), 2004
Enhanced purification of fetal liver hematopoietic stem cells using SLAM
I Kim, S He, OH Yilmaz, MJ Kiel, SJ Morrison
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