| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13833* | 2021 |
| Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease BR Stockwell, JPF Angeli, H Bayir, AI Bush, M Conrad, SJ Dixon, S Fulda, ... Cell 171 (2), 273-285, 2017 | 5419 | 2017 |
| Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress DD Zhang, M Hannink Molecular and cellular biology, 2003 | 1675 | 2003 |
| Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival SB Cullinan, D Zhang, M Hannink, E Arvisais, RJ Kaufman, JA Diehl Molecular and cellular biology 23 (20), 7198-7209, 2003 | 1452 | 2003 |
| Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex DD Zhang, SC Lo, JV Cross, DJ Templeton, M Hannink Molecular and cellular biology, 2004 | 1447 | 2004 |
| NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis M Dodson, R Castro-Portuguez, DD Zhang Redox biology 23, 101107, 2019 | 1408 | 2019 |
| The emerging role of the Nrf2–Keap1 signaling pathway in cancer MC Jaramillo, DD Zhang Genes & development 27 (20), 2179-2191, 2013 | 1405 | 2013 |
| Mechanistic studies of the Nrf2-Keap1 signaling pathway DD Zhang Drug metabolism reviews 38 (4), 769-789, 2006 | 1293 | 2006 |
| NRF2 and the Hallmarks of Cancer MR de la Vega, E Chapman, DD Zhang Cancer cell 34 (1), 21-43, 2018 | 1169 | 2018 |
| Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2 XJ Wang, Z Sun, NF Villeneuve, S Zhang, F Zhao, Y Li, W Chen, X Yi, ... Carcinogenesis 29 (6), 1235-1243, 2008 | 966 | 2008 |
| A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62 A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ... Molecular and cellular biology 30 (13), 3275-3285, 2010 | 898 | 2010 |
| Dual roles of Nrf2 in cancer A Lau, NF Villeneuve, Z Sun, PK Wong, DD Zhang Pharmacological research 58 (5-6), 262-270, 2008 | 809 | 2008 |
| Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response W Chen, Z Sun, XJ Wang, T Jiang, Z Huang, D Fang, DD Zhang Molecular cell 34 (6), 663-673, 2009 | 729 | 2009 |
| Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism D Ren, NF Villeneuve, T Jiang, T Wu, A Lau, HA Toppin, DD Zhang Proceedings of the National Academy of Sciences 108 (4), 1433-1438, 2011 | 689 | 2011 |
| p62 links autophagy and Nrf2 signaling T Jiang, B Harder, MR De La Vega, PK Wong, E Chapman, DD Zhang Free Radical Biology and Medicine 88, 199-204, 2015 | 593 | 2015 |
| Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy H Zheng, SA Whitman, W Wu, GT Wondrak, PK Wong, D Fang, DD Zhang Diabetes 60 (11), 3055-3066, 2011 | 574 | 2011 |
| The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy T Jiang, Z Huang, Y Lin, Z Zhang, D Fang, DD Zhang Diabetes 59 (4), 850-860, 2010 | 509 | 2010 |
| Regulation of the Nrf2–Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases NF Villeneuve, A Lau, DD Zhang Antioxidants & redox signaling 13 (11), 1699-1712, 2010 | 458 | 2010 |
| Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response Z Sun, YE Chin, DD Zhang Molecular and cellular biology, 2009 | 443 | 2009 |
| Modulating NRF2 in disease: timing is everything M Dodson, MR de la Vega, AB Cholanians, CJ Schmidlin, E Chapman, ... Annual review of pharmacology and toxicology 59 (1), 555-575, 2019 | 426 | 2019 |
Eli ChapmanThe University of ArizonaAdresse e-mail validée de pharmacy.arizona.edu
