Olivier de Jong
Olivier de Jong
Assistant Professor, Dept. of Pharmaceutics, Utrecht University
Geverifieerd e-mailadres voor uu.nl - Homepage
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Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes
OG de Jong, MC Verhaar, Y Chen, P Vader, H Gremmels, G Posthuma, ...
Journal of extracellular vesicles 1 (1), 18396, 2012
4632012
Endothelial cells require miR-214 to secrete exosomes that suppress senescence and induce angiogenesis in human and mouse endothelial cells
BWM van Balkom, OG De Jong, M Smits, J Brummelman, K den Ouden, ...
Blood, The Journal of the American Society of Hematology 121 (19), 3997-4006, 2013
4482013
Extracellular vesicles: potential roles in regenerative medicine
OG De Jong, BWM Van Balkom, RM Schiffelers, CVC Bouten, ...
Frontiers in immunology 5, 608, 2014
2282014
Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking
DE Murphy, OG de Jong, M Brouwer, MJ Wood, G Lavieu, RM Schiffelers, ...
Experimental & molecular medicine 51 (3), 1-12, 2019
1532019
Expression of PD‐L1 and PD‐L2 on human macrophages is up‐regulated by HIV‐1 and differentially modulated by IL‐10
M Rodríguez‐García, F Porichis, OG de Jong, K Levi, TJ Diefenbach, ...
Journal of leukocyte biology 89 (4), 507-515, 2011
962011
Extracellular vesicles as drug delivery systems: Why and how?
OM Elsharkasy, JZ Nordin, DW Hagey, OG de Jong, RM Schiffelers, ...
Advanced drug delivery reviews 159, 332-343, 2020
902020
Functional delivery of lipid-conjugated siRNA by extracellular vesicles
AJ O’Loughlin, I Mäger, OG de Jong, MA Varela, RM Schiffelers, ...
Molecular Therapy 25 (7), 1580-1587, 2017
862017
Drug delivery with extracellular vesicles: from imagination to innovation
OG De Jong, SAA Kooijmans, DE Murphy, L Jiang, MJW Evers, ...
Accounts of chemical research 52 (7), 1761-1770, 2019
662019
Exosomes from hypoxic endothelial cells have increased collagen crosslinking activity through up‐regulation of lysyl oxidase‐like 2
OG de Jong, BWM van Balkom, H Gremmels, MC Verhaar
Journal of cellular and molecular medicine 20 (2), 342-350, 2016
572016
A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
OG De Jong, DE Murphy, I Mager, E Willms, A Garcia Guerra, ...
Nature Communications 11, 1113, 2020
312020
Proteins in preservation fluid as predictors of delayed graft function in kidneys from donors after circulatory death
BWM van Balkom, H Gremmels, LSS Ooms, RJ Toorop, FJMF Dor, ...
Clinical Journal of the American Society of Nephrology 12 (5), 817-824, 2017
172017
Interfering with endolysosomal trafficking enhances release of bioactive exosomes
FG Ortega, MT Roefs, D de Miguel Perez, SA Kooijmans, OG de Jong, ...
Nanomedicine: Nanotechnology, Biology and Medicine 20, 102014, 2019
162019
Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis
SJ Vervoort, OG de Jong, MG Roukens, CL Frederiks, JF Vermeulen, ...
Elife 7, e27706, 2018
162018
The transcription factor Nrf2 protects angiogenic capacity of endothelial colony forming cells in high oxygen radical stress conditions
H Gremmels, OG de Jong, DH Hazenbrink, JO Fledderus, MC Verhaar
152017
Environmental influences on endothelial to mesenchymal transition in developing implanted cardiovascular tissue-engineered grafts
DEP Muylaert, OG de Jong, GGG Slaats, FE Nieuweboer, JO Fledderus, ...
Tissue Engineering Part B: Reviews 22 (1), 58-67, 2016
132016
Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition
OG de Jong, LM van der Waals, FRW Kools, MC Verhaar, ...
Journal of cellular physiology 234 (7), 10260-10269, 2019
112019
Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles
DE Murphy, OG de Jong, MJW Evers, M Nurazizah, RM Schiffelers, ...
Nano letters 21 (4), 1888-1895, 2021
42021
A post-insertion strategy for surface functionalization of bacterial and mammalian cell-derived extracellular vesicles
L Jiang, J Luirink, SAA Kooijmans, KPM van Kessel, W Jong, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (4), 129763, 2021
22021
The Small RNA Repertoire of Small Extracellular Vesicles Isolated From Donor Kidney Preservation Fluid Provides a Source for Biomarker Discovery for Organ Quality and …
H Gremmels, OG de Jong, RJ Toorop, L Michielsen, AD van Zuilen, ...
Transplantation direct 5 (9), 2019
22019
Hydrogel‐Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane‐Impermeable Cargo
J Van Hoeck, T Van de Vyver, A Harizaj, G Goetgeluk, P Merckx, J Liu, ...
Advanced Materials, 2008054, 2021
2021
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