Phenotypic characterization of human colorectal cancer stem cells P Dalerba, SJ Dylla, IK Park, R Liu, X Wang, RW Cho, T Hoey, A Gurney, ... Proceedings of the National Academy of Sciences 104 (24), 10158-10163, 2007 | 2756 | 2007 |
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells I Park, D Qian, M Kiel, MW Becker, M Pihalja, IL Weissman, SJ Morrison, ... Nature 423 (6937), 302-305, 2003 | 2382 | 2003 |
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation AV Molofsky, R Pardal, T Iwashita, IK Park, MF Clarke, SJ Morrison Nature 425 (6961), 962-967, 2003 | 1606 | 2003 |
Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy SJ Dylla, L Beviglia, IK Park, C Chartier, J Raval, L Ngan, K Pickell, ... PloS one 3 (6), e2428, 2008 | 750 | 2008 |
Bmi1, stem cells, and senescence regulation IK Park, SJ Morrison, MF Clarke The Journal of clinical investigation 113 (2), 175-179, 2004 | 666 | 2004 |
Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors A Gurney, F Axelrod, CJ Bond, J Cain, C Chartier, L Donigan, M Fischer, ... Proceedings of the National Academy of Sciences 109 (29), 11717-11722, 2012 | 637 | 2012 |
DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency T Hoey, WC Yen, F Axelrod, J Basi, L Donigian, S Dylla, M Fitch-Bruhns, ... Cell stem cell 5 (2), 168-177, 2009 | 504 | 2009 |
Differential gene expression profiling of adult murine hematopoietic stem cells IK Park, Y He, F Lin, OD Laerum, Q Tian, R Bumgarner, CA Klug, K Li, ... Blood, The Journal of the American Society of Hematology 99 (2), 488-498, 2002 | 241 | 2002 |
Serine/threonine protein phosphatases in the control of cell function AA Depaoli-Roach, IK Park, V Cerovsky, C Csortos, SD Durbin, MJ Kuntz, ... Advances in enzyme regulation 34, 199-224, 1994 | 219 | 1994 |
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors OO Akala, IK Park, D Qian, M Pihalja, MW Becker, MF Clarke Nature 453 (7192), 228-232, 2008 | 194 | 2008 |
Activation of Ca2+/Calmodulin-dependent Protein Kinase (CaM-kinase) IV by CaM-kinase Kinase in Jurkat T Lymphocytes (∗) IK Park, TR Soderling Journal of Biological Chemistry 270 (51), 30464-30469, 1995 | 138 | 1995 |
A genetic determinant that specifically regulates the frequency of hematopoietic stem cells SJ Morrison, D Qian, L Jerabek, BA Thiel, IK Park, PS Ford, MJ Kiel, ... The Journal of Immunology 168 (2), 635-642, 2002 | 132 | 2002 |
Molecular mechanism of the synergistic phosphorylation of phosphatase inhibitor-2. Cloning, expression, and site-directed mutagenesis of inhibitor-2. IK Park, P Roach, J Bondor, SP Fox, AA DePaoli-Roach Journal of Biological Chemistry 269 (2), 944-954, 1994 | 105 | 1994 |
Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase. I Park, AA DePaoli-Roach Journal of Biological Chemistry 269 (46), 28919-28928, 1994 | 91 | 1994 |
Isoform differences in substrate recognition by glycogen synthase kinases 3. alpha. and 3. beta. in the phosphorylation of phosphatase inhibitor 2 QM Wang, IK Park, CJ Fiol, PJ Roach, AA DePaoli-Roach Biochemistry 33 (1), 143-147, 1994 | 88 | 1994 |
Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells IK Park, CA Klug, K Li, L Jerabek, L Li, M Nanamori, RR Neubig, L Hood, ... Journal of Biological Chemistry 276 (2), 915-923, 2001 | 77 | 2001 |
Fluorescence studies on the interaction of inhibitor 2 and okadaic acid with the catalytic subunit of type 1 phosphoprotein phosphatases WD Picking, W Kudlicki, G Kramer, B Hardesty, JR Vandenheede, ... Biochemistry 30 (42), 10280-10287, 1991 | 44 | 1991 |
Combination Therapy For Treatment Of Disease CL Murriel, TC Hoey, AL Gurney, JM Roda, MK Srivastava, I Park, ... US Patent App. 14/928,271, 2016 | 17 | 2016 |
Combination therapy for treatment of disease CL Murriel, TC Hoey, AL Gurney, JM Roda, MK Srivastava, I Park, ... US Patent 11,046,760, 2021 | 9 | 2021 |
PHOSPHATASE INHIBITOR-2 FUNCTIONS AS A POSITIVE REGULATOR OF GLYCOGEN-METABOLISM IN SACCHAROMYCES-CEREVISIAE AA DEPAOLIROACH, IK Park, M Khalil, JF Cannon FASEB JOURNAL 7 (7), A1157-A1157, 1993 | 6 | 1993 |