| Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates V Filipe, A Hawe, W Jiskoot Pharmaceutical research 27 (5), 796-810, 2010 | 1709 | 2010 |
| Extrinsic fluorescent dyes as tools for protein characterization A Hawe, M Sutter, W Jiskoot Pharmaceutical research 25 (7), 1487-1499, 2008 | 1145 | 2008 |
| Protein instability in poly (lactic-co-glycolic acid) microparticles M van de Weert, WE Hennink, W Jiskoot Pharmaceutical research 17 (10), 1159-1167, 2000 | 853 | 2000 |
| Structure-immunogenicity relationships of therapeutic proteins S Hermeling, DJA Crommelin, H Schellekens, W Jiskoot Pharmaceutical research 21 (6), 897-903, 2004 | 710 | 2004 |
| Chitosan-based delivery systems for protein therapeutics and antigens M Amidi, E Mastrobattista, W Jiskoot, WE Hennink Advanced drug delivery reviews 62 (1), 59-82, 2010 | 676 | 2010 |
| Identification of formaldehyde-induced modifications in proteins: reactions with model peptides B Metz, GFA Kersten, P Hoogerhout, HF Brugghe, HAM Timmermans, ... Journal of Biological Chemistry 279 (8), 6235-6243, 2004 | 667 | 2004 |
| Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality JF Carpenter, TW Randolph, WIM Jiskoot, DJA Crommelin, CR Middaugh, ... Journal of pharmaceutical sciences 98 (4), 1201-1205, 2009 | 563 | 2009 |
| Microneedle technologies for (trans) dermal drug and vaccine delivery K Van Der Maaden, W Jiskoot, J Bouwstra Journal of controlled release 161 (2), 645-655, 2012 | 544 | 2012 |
| Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system M Amidi, SG Romeijn, G Borchard, HE Junginger, WE Hennink, W Jiskoot Journal of controlled release 111 (1-2), 107-116, 2006 | 464 | 2006 |
| ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity MI De Jonge, G Pehau-Arnaudet, MM Fretz, F Romain, D Bottai, P Brodin, ... Journal of bacteriology 189 (16), 6028-6034, 2007 | 361 | 2007 |
| Strategies for the assessment of protein aggregates in pharmaceutical biotech product development J Den Engelsman, P Garidel, R Smulders, H Koll, B Smith, S Bassarab, ... Pharmaceutical research 28 (4), 920-933, 2011 | 324 | 2011 |
| N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model M Amidi, SG Romeijn, JC Verhoef, HE Junginger, L Bungener, ... Vaccine 25 (1), 144-153, 2007 | 283 | 2007 |
| Shifting paradigms: biopharmaceuticals versus low molecular weight drugs DJA Crommelin, G Storm, R Verrijk, L de Leede, W Jiskoot, WE Hennink International journal of pharmaceutics 266 (1-2), 3-16, 2003 | 271 | 2003 |
| Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins E Mastrobattista, GA Koning, L van Bloois, ACS Filipe, W Jiskoot, G Storm Journal of Biological Chemistry 277 (30), 27135-27143, 2002 | 249 | 2002 |
| CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses RA Rosalia, LJ Cruz, S van Duikeren, AT Tromp, AL Silva, W Jiskoot, ... Biomaterials 40, 88-97, 2015 | 246 | 2015 |
| Antibody response to aggregated human interferon alpha2b in wild-type and transgenic immune tolerant mice depends on type and level of aggregation S Hermeling, H Schellekens, C Maas, MFBG Gebbink, DJA Crommelin, ... Journal of pharmaceutical sciences 95 (5), 1084-1096, 2006 | 246 | 2006 |
| Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release W Jiskoot, TW Randolph, DB Volkin, CR Middaugh, C Schöneich, ... Journal of pharmaceutical sciences 101 (3), 946-954, 2012 | 245 | 2012 |
| Structural properties of monoclonal antibody aggregates induced by freeze–thawing and thermal stress A Hawe, JC Kasper, W Friess, W Jiskoot European journal of pharmaceutical sciences 38 (2), 79-87, 2009 | 243 | 2009 |
| Synthesis, characterization and in vitro biological properties of O-methyl free N, N, N-trimethylated chitosan RJ Verheul, M Amidi, S van der Wal, E van Riet, W Jiskoot, WE Hennink Biomaterials 29 (27), 3642-3649, 2008 | 238 | 2008 |
| Forced degradation of therapeutic proteins A Hawe, M Wiggenhorn, M van de Weert, JHO Garbe, H Mahler, ... Journal of pharmaceutical sciences 101 (3), 895-913, 2012 | 229 | 2012 |
Wim HenninkProfessor, Department of Pharmaceutics, Utrecht University, The NetherlandsVerified email at uu.nl
