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Wim Jiskoot
Wim Jiskoot
Leiden University, Coriolis Pharma
Geverifieerd e-mailadres voor lacdr.leidenuniv.nl
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Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates
V Filipe, A Hawe, W Jiskoot
Pharmaceutical research 27 (5), 796-810, 2010
17122010
Extrinsic fluorescent dyes as tools for protein characterization
A Hawe, M Sutter, W Jiskoot
Pharmaceutical research 25 (7), 1487-1499, 2008
11452008
Protein instability in poly (lactic-co-glycolic acid) microparticles
M van de Weert, WE Hennink, W Jiskoot
Pharmaceutical research 17 (10), 1159-1167, 2000
8532000
Structure-immunogenicity relationships of therapeutic proteins
S Hermeling, DJA Crommelin, H Schellekens, W Jiskoot
Pharmaceutical research 21 (6), 897-903, 2004
7092004
Chitosan-based delivery systems for protein therapeutics and antigens
M Amidi, E Mastrobattista, W Jiskoot, WE Hennink
Advanced drug delivery reviews 62 (1), 59-82, 2010
6782010
Identification of formaldehyde-induced modifications in proteins: reactions with model peptides
B Metz, GFA Kersten, P Hoogerhout, HF Brugghe, HAM Timmermans, ...
Journal of Biological Chemistry 279 (8), 6235-6243, 2004
6672004
Overlooking subvisible particles in therapeutic protein products: gaps that may compromise product quality
JF Carpenter, TW Randolph, WIM Jiskoot, DJA Crommelin, CR Middaugh, ...
Journal of pharmaceutical sciences 98 (4), 1201-1205, 2009
5662009
Microneedle technologies for (trans) dermal drug and vaccine delivery
K Van Der Maaden, W Jiskoot, J Bouwstra
Journal of controlled release 161 (2), 645-655, 2012
5452012
Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system
M Amidi, SG Romeijn, G Borchard, HE Junginger, WE Hennink, W Jiskoot
Journal of controlled release 111 (1-2), 107-116, 2006
4652006
ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity
MI De Jonge, G Pehau-Arnaudet, MM Fretz, F Romain, D Bottai, P Brodin, ...
Journal of bacteriology 189 (16), 6028-6034, 2007
3622007
Strategies for the assessment of protein aggregates in pharmaceutical biotech product development
J Den Engelsman, P Garidel, R Smulders, H Koll, B Smith, S Bassarab, ...
Pharmaceutical research 28 (4), 920-933, 2011
3242011
N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model
M Amidi, SG Romeijn, JC Verhoef, HE Junginger, L Bungener, ...
Vaccine 25 (1), 144-153, 2007
2832007
Shifting paradigms: biopharmaceuticals versus low molecular weight drugs
DJA Crommelin, G Storm, R Verrijk, L de Leede, W Jiskoot, WE Hennink
International journal of pharmaceutics 266 (1-2), 3-16, 2003
2712003
Functional characterization of an endosome-disruptive peptide and its application in cytosolic delivery of immunoliposome-entrapped proteins
E Mastrobattista, GA Koning, L van Bloois, ACS Filipe, W Jiskoot, G Storm
Journal of Biological Chemistry 277 (30), 27135-27143, 2002
2502002
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
RA Rosalia, LJ Cruz, S van Duikeren, AT Tromp, AL Silva, W Jiskoot, ...
Biomaterials 40, 88-97, 2015
2462015
Antibody response to aggregated human interferon alpha2b in wild-type and transgenic immune tolerant mice depends on type and level of aggregation
S Hermeling, H Schellekens, C Maas, MFBG Gebbink, DJA Crommelin, ...
Journal of pharmaceutical sciences 95 (5), 1084-1096, 2006
2462006
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release
W Jiskoot, TW Randolph, DB Volkin, CR Middaugh, C Schöneich, ...
Journal of pharmaceutical sciences 101 (3), 946-954, 2012
2452012
Structural properties of monoclonal antibody aggregates induced by freeze–thawing and thermal stress
A Hawe, JC Kasper, W Friess, W Jiskoot
European journal of pharmaceutical sciences 38 (2), 79-87, 2009
2432009
Synthesis, characterization and in vitro biological properties of O-methyl free N, N, N-trimethylated chitosan
RJ Verheul, M Amidi, S van der Wal, E van Riet, W Jiskoot, WE Hennink
Biomaterials 29 (27), 3642-3649, 2008
2382008
mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability
L Schoenmaker, D Witzigmann, JA Kulkarni, R Verbeke, G Kersten, ...
International Journal of Pharmaceutics 601, 120586, 2021
2322021
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