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Hanneke Vlaming
Hanneke Vlaming
Harvard Medical School
Geverifieerd e-mailadres voor hms.harvard.edu
Titel
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Jaar
The upstreams and downstreams of H3K79 methylation by DOT1L
H Vlaming, F van Leeuwen
Chromosoma 125 (4), 593-605, 2016
742016
Yeast PP4 Interacts with ATR Homolog Ddc2-Mec1 and Regulates Checkpoint Signaling
N Hustedt, A Seeber, R Sack, M Tsai-Pflugfelder, B Bhullar, H Vlaming, ...
Molecular cell 57 (2), 273-289, 2015
652015
Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo
H Vlaming, T van Welsem, EL de Graaf, D Ontoso, AFM Altelaar, ...
EMBO reports 15 (10), 1077-1084, 2014
432014
HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis
CD Zimberlin, C Lancini, R Sno, SL Rosekrans, CM McLean, H Vlaming, ...
The FASEB Journal 29 (5), 2070-2080, 2015
422015
Dot1 promotes H2B ubiquitination by a methyltransferase-independent mechanism
T van Welsem, T Korthout, R Ekkebus, D Morais, TM Molenaar, ...
Nucleic acids research 46 (21), 11251-11261, 2018
302018
Direct screening for chromatin status on DNA barcodes in yeast delineates the regulome of H3K79 methylation by Dot1
H Vlaming, TM Molenaar, T van Welsem, DW Poramba-Liyanage, ...
eLife 5, e18919, 2016
272016
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma
H Vlaming, CM McLean, T Korthout, MF Alemdehy, S Hendriks, C Lancini, ...
The EMBO journal 38 (14), e101564, 2019
252019
The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells
EM Kwesi-Maliepaard, MA Aslam, MF Alemdehy, T van den Brand, ...
Proceedings of the National Academy of Sciences 117 (34), 20706-20716, 2020
222020
Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.
IJ Stulemeijer, D De Vos, K Van Harten, OK Joshi, O Blomberg, ...
Scientific reports 5, 9824-9824, 2015
182015
Crosstalk between aging and the epigenome
H Vlaming, F van Leeuwen
Epigenomics 4 (1), 5-7, 2012
112012
Strength is in engagement: The rise of an online scientific community during the COVID‐19 pandemic
CE Cucinotta, BJE Martin, M Noé González, P Raman, VB Teif, H Vlaming
EMBO reports 22 (5), e52612, 2021
42021
Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential
H Vlaming, CA Mimoso, AR Field, BJE Martin, K Adelman
Nature Structural & Molecular Biology 29, 613–620, 2022
32022
Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies
L Kollenstart, SC van der Horst, K Vreeken, GMC Janssen, F Martino, ...
Scientific reports 11 (1), 1-17, 2021
22021
Modeling Distributive Histone Modification by Dot1 Methyltransferases: From Mechanism to Biological Insights.
D De Vos, H Vlaming, BM Bakker, F Van Leeuwen
Epigenetics and Systems Biology, 117–141, 2017
22017
Connecting the dots: Delineating the regulation of H3K79 methylation by Dot1
H Vlaming
Universiteit van Amsterdam, 2017
2017
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro
EM Kwesi-Maliepaard, M Malik, T Van Welsem, R Van Doorn, ...
Frontiers in Genetics, 3178, 0
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Artikelen 1–16