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Malgorzata Krajewska
Malgorzata Krajewska
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Gene expression analysis identifies global gene dosage sensitivity in cancer
RSN Fehrmann, JM Karjalainen, M Krajewska, HJ Westra, D Maloney, ...
Nature genetics 47 (2), 115-125, 2015
3872015
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation
M Krajewska, R Dries, AV Grassetti, S Dust, Y Gao, H Huang, B Sharma, ...
Nature communications 10 (1), 1757, 2019
1892019
Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination
M Krajewska, AM Heijink, YJWM Bisselink, RI Seinstra, HHW Silljé, ...
Oncogene 32 (24), 3001-3008, 2013
1322013
The DNA damage response during mitosis
AM Heijink, M Krajewska, MATM van Vugt
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 750 (1 …, 2013
1162013
ATR inhibition preferentially targets homologous recombination-deficient tumor cells
M Krajewska, RSN Fehrmann, PM Schoonen, S Labib, EGE De Vries, ...
Oncogene 34 (26), 3474-3481, 2015
1132015
Regulators of homologous recombination repair as novel targets for cancer treatment
M Krajewska, RSN Fehrmann, EGE De Vries, MATM van Vugt
Frontiers in genetics 6, 134139, 2015
992015
Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma
I Bayles, M Krajewska, WD Pontius, A Saiakhova, JJ Morrow, C Bartels, ...
The Journal of Clinical Investigation 129 (10), 4377-4392, 2019
352019
Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes
S Sengupta, S Das, AC Crespo, AM Cornel, AG Patel, NR Mahadevan, ...
Nature cancer 3 (10), 1228-1246, 2022
242022
Synergistic anti-tumor effect of combining selective CDK7 and BRD4 inhibition in neuroblastoma
Y Gao, M Volegova, N Nasholm, S Das, N Kwiatkowski, BJ Abraham, ...
Frontiers in Oncology 11, 773186, 2022
122022
Cell lineage as a predictor of immune response in neuroblastoma
S Sengupta, S Das, A Crespo, B Miller, B Sharma, S Zhang, R Dries, ...
bioRxiv, 2021.01. 29.428154, 2021
72021
Building a great wall around mitosis: evolutionary conserved roles for the Greatwall/MASTL kinases in securing chromosome stability
M Krajewska, MATM van Vugt
Cell Cycle 9 (19), 3842-3847, 2010
32010
The DNA Damage Response During Mitosis
M Krajewska, AM Heijink, MATM van Vugt
Targeting Homologous Recombination Repair In Cancer Cells 750 (1-2), 91, 2014
12014
Investigation of gene expression data of 77,840 samples reveals global gene dosage sensitivity
RSN Fehrmann, JM Karjalainen, M Krajewska, HJ Westra, D Maloney, ...
Targeting Homologous Recombination Repair In Cancer Cells, 121, 2014
12014
Abstract PR04: Targeting super-enhancer driven oncogene transcription through cyclin-dependent kinase inhibitors
M Krajewska, NF Moore, E Chipumuro, T Zhang, E Marco, C Hatheway, ...
Cancer Research 76 (2_Supplement), PR04-PR04, 2016
2016
Krajewska M, Fehrmann RS, Labib S, de Vries EG, Franke L and van Vugt MA. ATR Signaling is Essential for Survival of Homologous Recombination-Deficient Tumor Cells. under revision
M Krajewska
Targeting Homologous Recombination Repair In Cancer Cells, 197, 2014
2014
Wee1 as a Therapeutic Target in Cervical Cancer
M Krajewska, H Wieringa, M Everts, GBA Wisman, AGJ van der Zee, ...
Targeting Homologous Recombination Repair In Cancer Cells, 69, 2014
2014
ATR Signaling is Essential for Survival of Homologous Recombination-Deficient Tumor Cells
M Krajewska, RSN Fehrmann, S Labib, EGE de Vries, L Franke, ...
Targeting Homologous Recombination Repair In Cancer Cells, 145, 2014
2014
Forced Activation of Cdk1 via Wee1 Inhibition Impairs Homologous Recombination in Cancer Cells
M Krajewska, AM Heijink, YJWM Bisselink, RI Seinstra, HHW Silljé, ...
Targeting Homologous Recombination Repair In Cancer Cells 32 (24), 45, 2014
2014
SP-02: Cell Cycle Regulation of the DNA Damage Response: Targeting WEE1 Kinase to Impair DNA Repair.
M Van Vugt, M Krajewska, H Sillje, AM Heijink, Y Bisselink, EGE de Vries
Radiotherapy and Oncology, 21, 2012
2012
Small-Molecule Inhibition of Mettl3 Suppresses Neuroblastoma Tumor Growth and Promotes Differentiation
M Pomaville, Z Jiang, P Wang, M Chennakesavalu, C Ye, R Ge, Z Zou, ...
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