Characterization of the cell-free DNA released by cultured cancer cells AJ Bronkhorst, JF Wentzel, J Aucamp, E Van Dyk, L Du Plessis, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (1), 157-165, 2016 | 198 | 2016 |
Antimicrobial peptides: the Achilles’ heel of antibiotic resistance? A Lewies, LH Du Plessis, JF Wentzel Probiotics and antimicrobial proteins 11, 370-381, 2019 | 154 | 2019 |
Measuring DNA modifications with the comet assay: a compendium of protocols A Collins, P Møller, G Gajski, S Vodenková, A Abdulwahed, D Anderson, ... Nature protocols 18 (3), 929-989, 2023 | 101 | 2023 |
Assessing the DNA methylation status of single cells with the comet assay JF Wentzel, C Gouws, C Huysamen, E Van Dyk, G Koekemoer, ... Analytical biochemistry 400 (2), 190-194, 2010 | 83 | 2010 |
Interactions of the antimicrobial peptide nisin Z with conventional antibiotics and the use of nanostructured lipid carriers to enhance antimicrobial activity A Lewies, JF Wentzel, A Jordaan, C Bezuidenhout, LH Du Plessis International journal of pharmaceutics 526 (1-2), 244-253, 2017 | 80 | 2017 |
The potential use of natural and structural analogues of antimicrobial peptides in the fight against neglected tropical diseases A Lewies, JF Wentzel, G Jacobs, LH Du Plessis Molecules 20 (8), 15392-15433, 2015 | 71 | 2015 |
The antimicrobial peptide nisin Z induces selective toxicity and apoptotic cell death in cultured melanoma cells A Lewies, JF Wentzel, HC Miller, LH Du Plessis Biochimie 144, 28-40, 2018 | 64 | 2018 |
Evaluation of the cytotoxic properties, gene expression profiles and secondary signalling responses of cultured cells exposed to fumonisin B1, deoxynivalenol and zearalenone … JF Wentzel, MJ Lombard, LH Du Plessis, L Zandberg Archives of toxicology 91, 2265-2282, 2017 | 59 | 2017 |
Efflux as a mechanism of antimicrobial drug resistance in clinical relevant microorganisms: the role of efflux inhibitors C Willers, JF Wentzel, LH Du Plessis, C Gouws, JH Hamman Expert opinion on therapeutic targets 21 (1), 23-36, 2017 | 53 | 2017 |
Exposure to high levels of fumarate and succinate leads to apoptotic cytotoxicity and altered global DNA methylation profiles in vitro JF Wentzel, A Lewies, AJ Bronkhorst, E Van Dyk, LH Du Plessis, ... Biochimie 135, 28-34, 2017 | 51 | 2017 |
Synthesis, in vitro antimalarial activities and cytotoxicities of amino-artemisinin-ferrocene derivatives C De Lange, D Coertzen, FJ Smit, JF Wentzel, HN Wong, LM Birkholtz, ... Bioorganic & medicinal chemistry letters 28 (3), 289-292, 2018 | 41 | 2018 |
Sequence analysis of cell-free DNA derived from cultured human bone osteosarcoma (143B) cells AJ Bronkhorst, JF Wentzel, V Ungerer, DL Peters, J Aucamp, ... Tumor Biology 40 (9), 1010428318801190, 2018 | 40 | 2018 |
Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1, 2-disubstituted ferrocene hybrids C De Lange, D Coertzen, FJ Smit, JF Wentzel, HN Wong, LM Birkholtz, ... Bioorganic & Medicinal Chemistry Letters 28 (19), 3161-3163, 2018 | 33 | 2018 |
Using a medium-throughput comet assay to evaluate the global DNA methylation status of single cells A Lewies, E Van Dyk, JF Wentzel, PJ Pretorius Frontiers in genetics 5, 98207, 2014 | 29 | 2014 |
The cytotoxic, antimicrobial and anticancer properties of the antimicrobial peptide nisin Z alone and in combination with conventional treatments A Lewies, LH Du Plessis, JF Wentzel Cytotoxicity 25, 21, 2018 | 22 | 2018 |
Preliminary evaluation of artemisinin–cholesterol conjugates as potential drugs for the treatment of intractable forms of malaria and tuberculosis M Morake, D Coertzen, A Ngwane, JF Wentzel, HN Wong, FJ Smit, ... ChemMedChem 13 (1), 67-77, 2018 | 16 | 2018 |
Reference gene selection for in vitro cell-free DNA analysis and gene expression profiling AJ Bronkhorst, J Aucamp, JF Wentzel, PJ Pretorius Clinical biochemistry 49 (7-8), 606-608, 2016 | 15 | 2016 |
Anti-melanoma activities of artemisone and prenylated amino-artemisinins in combination with known anticancer drugs HN Wong, A Lewies, M Haigh, JM Viljoen, JF Wentzel, RK Haynes, ... Frontiers in Pharmacology 11, 558894, 2020 | 13 | 2020 |
Probiotics Antimicrob A Lewies, LH Du Plessis, JF Wentzel Proteins 11, 370-381, 2019 | 11 | 2019 |
Consensus sequence determination and elucidation of the evolutionary history of a rotavirus Wa variant reveal a close relationship to various Wa variants derived from the … JF Wentzel, L Yuan, S Rao, AA van Dijk, HG O’Neill Infection, Genetics and Evolution 20, 276-283, 2013 | 11 | 2013 |