Joel Rothman
Joel Rothman
Professor of MCD Biology, University of California, Santa Barbara
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Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.
JH Rothman, CT Yamashiro, CK Raymond, PM Kane, TH Stevens
The Journal of cell biology 109 (1), 93-100, 1989
Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance
WB Derry, AP Putzke, JH Rothman
Science 294 (5542), 591-595, 2001
Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway
JH Rothman, TH Stevens
Cell 47 (6), 1041-1051, 1986
PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors
G Ammerer, CP Hunter, JH Rothman, GC Saari, LA Valls, TH Stevens
Molecular and cellular biology, 1986
Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide
LA Valls, CP Hunter, JH Rothman, TH Stevens
Cell 48 (5), 887-897, 1987
Cytokinesis and Midzone Microtubule Organization inCaenorhabditis elegans Require the Kinesin-like Protein ZEN-4
WB Raich, AN Moran, JH Rothman, J Hardin
Molecular biology of the cell 9 (8), 2037-2049, 1998
A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting
JH Rothman, CK Raymond, T Gilbert, PJ O'Hara, TH Stevens
Cell 61 (6), 1063-1074, 1990
Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae.
JH Rothman, I Howald, TH Stevens
The EMBO journal 8 (7), 2057-2065, 1989
end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos
J Zhu, RJ Hill, PJ Heid, M Fukuyama, A Sugimoto, JR Priess, JH Rothman
Genes & development 11 (21), 2883-2896, 1997
Baculovirus p35 prevents developmentally programmed cell death and rescues a ced‐9 mutant in the nematode Caenorhabditis elegans.
A Sugimoto, PD Friesen, JH Rothman
The EMBO Journal 13 (9), 2023-2028, 1994
Restriction of mesendoderm to a single blastomere by the combined action of SKN-1 and a GSK-3β homolog is mediated by MED-1 and-2 in C. elegans
MF Maduro, MD Meneghini, B Bowerman, G Broitman-Maduro, ...
Molecular cell 7 (3), 475-485, 2001
Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y.
TH Stevens, JH Rothman, GS Payne, R Schekman
The Journal of cell biology 102 (5), 1551-1557, 1986
Making Worm Guts: The Gene Regulatory Network of the Caenorhabditis elegans Endoderm
MF Maduro, JH Rothman
Developmental biology 246 (1), 68-85, 2002
ELT-5 and ELT-6 are required continuously to regulate epidermal seam cell differentiation and cell fusion in C. elegans
K Koh, JH Rothman
Oxford University Press for The Company of Biologists Limited 128 (15), 2867 …, 2001
Reprogramming of early embryonic blastomeres into endodermal progenitors by a Caenorhabditis elegans GATA factor
J Zhu, T Fukushige, JD McGhee, JH Rothman
Genes & development 12 (24), 3809-3814, 1998
Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene.
JH Rothman, CP Hunter, LA Valls, TH Stevens
Proceedings of the National Academy of Sciences 83 (10), 3248-3252, 1986
Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole.
CJ Roberts, G Pohlig, JH Rothman, TH Stevens
The Journal of cell biology 108 (4), 1363-1373, 1989
C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline
M Fukuyama, AE Rougvie, JH Rothman
Current Biology 16 (8), 773-779, 2006
dad‐1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates.
A Sugimoto, RR Hozak, T Nakashima, T Nishimoto, JH Rothman
The EMBO Journal 14 (18), 4434-4441, 1995
Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans
TA Bloss, ES Witze, JH Rothman
Nature 424 (6952), 1066-1071, 2003
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