| Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (PCB3) in female rats K Dhakal, E Uwimana, A Adamcakova-Dodd, PS Thorne, HJ Lehmler, ... Chemical research in toxicology 27 (8), 1411-1420, 2014 | 48 | 2014 |
| Human CYP2A6, CYP2B6, and CYP2E1 atropselectively metabolize polychlorinated biphenyls to hydroxylated metabolites E Uwimana, P Ruiz, X Li, HJ Lehmler Environmental science & technology 53 (4), 2114-2123, 2018 | 38 | 2018 |
| 2, 2′, 3, 5′, 6-Pentachlorobiphenyl (PCB 95) is atropselectively metabolized to para-hydroxylated metabolites by human liver microsomes E Uwimana, X Li, HJ Lehmler Chemical research in toxicology 29 (12), 2108-2110, 2016 | 25 | 2016 |
| Microsomal metabolism of prochiral polychlorinated biphenyls results in the enantioselective formation of chiral metabolites E Uwimana, A Maiers, X Li, HJ Lehmler Environmental science & technology 51 (3), 1820-1829, 2017 | 22 | 2017 |
| Human liver microsomes atropselectively metabolize 2, 2′, 3, 4′, 6-pentachlorobiphenyl (PCB 91) to a 1, 2-shift product as the major metabolite E Uwimana, X Li, HJ Lehmler Environmental science & technology 52 (10), 6000-6008, 2018 | 21 | 2018 |
| Subacute nicotine co-exposure has no effect on 2, 2′, 3, 5′, 6-pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat M Stamou, E Uwimana, BM Flannery, I Kania-Korwel, HJ Lehmler, ... Toxicology 338, 59-68, 2015 | 16 | 2015 |
| Atropselective oxidation of 2, 2′, 3, 3′, 4, 6′-hexachlorobiphenyl (PCB 132) to hydroxylated metabolites by human liver microsomes and its implications for PCB 132 neurotoxicity E Uwimana, B Cagle, C Yeung, X Li, EV Patterson, JA Doorn, HJ Lehmler Toxicological sciences 171 (2), 406-420, 2019 | 15 | 2019 |
| Probing the role of CYP2 enzymes in the atropselective metabolism of polychlorinated biphenyls using liver microsomes from transgenic mouse models HJ Lehmler, E Uwimana, LE Dean, N Kovalchuk, QY Zhang, X Ding Chemical research in toxicology 35 (12), 2310-2323, 2022 | 2 | 2022 |
| In vitro airway models from mice, rhesus macaques, and humans maintain species differences in xenobiotic metabolism and cellular responses to naphthalene LVW J Kelty, N Kovalchuk, E Uwimana, L Yin, X Ding American Journal of Physiology-Lung Cellular and Molecular Physiology, 2022 | 1 | 2022 |
| Impact of Ergothioneine Pretreatment on Naphthalene Toxicity in the Mouse Lung VJ Brown, N Kovalchuk, E Uwimana, X Ding, LS Van Winkle TP119. TP119 NOVEL IN VITRO STUDIES OF THE AIRWAYS AND LUNG, A4522-A4522, 2021 | | 2021 |
| Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes: Involvement of Arene Oxide Intermediates HJL Eric Uwimana, Xueshu Li, Coby Yeung, Eric V. Patterson bioRxiv, The PrePrint Server for Biology. doi: https://doi.org/10.1101/373837, 2018 | | 2018 |
| Probing the PCB metabolome: metabolism of chiral and non-chiral polychlorinated biphenyls to chiral hydroxylated metabolites in humans and rats E Uwimana The University of Iowa, 2018 | | 2018 |
| metabolism of 2, 2’, 3, 5’, 6-pentachlorobiphenyl (PCB 95): effect of microsomal epoxide hydrolase inhibition J Shen, E Uwimana, HJ Lehmler | | |
| In vitro metabolism of 2, 2’, 3, 5’, 6-pentachlorobiphenyl (PCB 95): effect of microsomal epoxide hydrolase inhibition J Shen, E Uwimana, HJ Lehmler | | |
Hans-Joachim LehmlerProfessor, Department of Occupational and Environmental Health, University of IowaVerified email at uiowa.edu
