Miklos Guttman
Miklos Guttman
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HIV-1 neutralizing antibodies induced by native-like envelope trimers
RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ...
Science 349 (6244), 2015
3952015
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env
Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ...
Nature structural & molecular biology 22 (7), 522, 2015
2472015
Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes
SW de Taeye, G Ozorowski, AT de la Peņa, M Guttman, JP Julien, ...
Cell 163 (7), 1702-1715, 2015
2222015
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ...
Nature Methods 16 (7), 595-602, 2019
1372019
An unexpected twist in viral capsid maturation
I Gertsman, L Gan, M Guttman, K Lee, JA Speir, RL Duda, RW Hendrix, ...
Nature 458 (7238), 646-650, 2009
1362009
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design
J Gorman, C Soto, MM Yang, TM Davenport, M Guttman, RT Bailer, ...
Nature structural & molecular biology 23 (1), 81, 2016
1262016
CD4-induced activation in a soluble HIV-1 Env trimer
M Guttman, NK Garcia, A Cupo, T Matsui, JP Julien, RW Sanders, ...
Structure 22 (7), 974-984, 2014
1162014
Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra
M Guttman, DD Weis, JR Engen, KK Lee
Journal of the American Society for Mass Spectrometry 24 (12), 1906-1912, 2013
1142013
Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env
M Guttman, A Cupo, JP Julien, RW Sanders, IA Wilson, JP Moore, KK Lee
Nature communications 6 (1), 1-11, 2015
1082015
Sequential and simultaneous immunization of rabbits with HIV-1 envelope glycoprotein SOSIP. 664 trimers from clades A, B and C
PJ Klasse, CC LaBranche, TJ Ketas, G Ozorowski, A Cupo, P Pugach, ...
PLoS pathogens 12 (9), e1005864, 2016
922016
Local and global structural drivers for the photoactivation of the orange carotenoid protein
S Gupta, M Guttman, RL Leverenz, K Zhumadilova, EG Pawlowski, ...
Proceedings of the National Academy of Sciences 112 (41), E5567-E5574, 2015
902015
Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization
AT de la Peņa, JP Julien, SW de Taeye, F Garces, M Guttman, ...
Cell reports 20 (8), 1805-1817, 2017
842017
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
MG Joyce, B Zhang, L Ou, M Chen, GY Chuang, A Druz, WP Kong, YT Lai, ...
Nature structural & molecular biology 23 (9), 811, 2016
742016
Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120
M Guttman, M Kahn, NK Garcia, SL Hu, KK Lee
Journal of virology 86 (16), 8750-8764, 2012
742012
Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers
RP Ringe, A Yasmeen, G Ozorowski, EP Go, LK Pritchard, M Guttman, ...
Journal of virology 89 (23), 12189-12210, 2015
722015
All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins
M Guttman, P Weinkam, A Sali, KK Lee
Structure 21 (3), 321-331, 2013
682013
Interactions of the NPXY microdomains of the low density lipoprotein receptor‐related protein 1
M Guttman, GN Betts, H Barnes, M Ghassemian, P van der Geer, ...
Proteomics 9 (22), 5016-5028, 2009
622009
Dynamic changes during acid-induced activation of influenza hemagglutinin
NK Garcia, M Guttman, JL Ebner, KK Lee
Structure 23 (4), 665-676, 2015
552015
HIV-1 vaccines. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science 349: aac4223
RW Sanders, MJ Van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ...
552015
Structure of the minimal interface between ApoE and LRP
M Guttman, JH Prieto, TM Handel, PJ Domaille, EA Komives
Journal of molecular biology 398 (2), 306-319, 2010
552010
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