Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone MJ Costanzo, SC Yabut, HR Almond, P Andrade-Gordon, TW Corcoran, ... Journal of medicinal chemistry 46 (18), 3865-3876, 2003 | 104 | 2003 |
Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain R Recacha, A Boulet, F Jollivet, S Monier, A Houdusse, B Goud, AR Khan Structure 17 (1), 21-30, 2009 | 90 | 2009 |
Nonpeptide inhibitors of cathepsin G: optimization of a novel β-ketophosphonic acid lead by structure-based drug design MN Greco, MJ Hawkins, ET Powell, HR Almond, TW Corcoran, ... Journal of the American Chemical Society 124 (15), 3810-3811, 2002 | 83 | 2002 |
Crystal structure of human carbonic anhydrase II complexed with ananti-convulsant sugar sulphamate R Recacha, MJ Costanzo, BE Maryanoff, D Chattopadhyay Biochemical Journal 361 (3), 437-441, 2002 | 62 | 2002 |
Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV D Rasina, M Otikovs, J Leitans, R Recacha, OV Borysov, I Kanepe-Lapsa, ... Journal of Medicinal Chemistry 59 (1), 374-387, 2016 | 59 | 2016 |
Structure of the nucleotide-binding domain of Plasmodium falciparum rab6 in the GDP-bound form D Chattopadhyay, G Langsley, M Carson, R Recacha, L DeLucas, ... Acta Crystallographica Section D: Biological Crystallography 56 (8), 937-944, 2000 | 48 | 2000 |
Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection C Santiago, G Mugdal, J Reguera, R Recacha, S Albretch, ... Scientific Reports, 2017 | 34 | 2017 |
A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein MH Wilson, S Rajan, A Danoff, RJ White, MR Hensley, VH Quinlivan, ... PLoS Genetics 16 (8), e1008941, 2020 | 24 | 2020 |
Structural aspects of Rab6–effector complexes H Fernandes, E Franklin, R Recacha, A Houdusse, B Goud, AR Khan Biochemical Society Transactions 37 (5), 1037-1041, 2009 | 24 | 2009 |
Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors R Recacha, J Leitans, I Akopjana, L Aprupe, P Trapencieris, K Jaudzems, ... Acta Crystallographica Section F: Structural Biology Communications 71 (12 …, 2015 | 16 | 2015 |
Structure of human α-thrombin complexed with RWJ-51438 at 1.7 Ĺ: unusual perturbation of the 60A–60I insertion loop R Recacha, MJ Costanzo, BE Maryanoff, M Carson, L DeLucas, ... Acta Crystallographica Section D: Biological Crystallography 56 (11), 1395-1400, 2000 | 13 | 2000 |
Toxoplasma gondii adenosine kinase: expression, purification, characterization, crystallization and preliminary crystallographic analysis R Recacha, A Talalaev, L DeLucas, D Chattopadhyay Acta Crystallographica Section D: Biological Crystallography 56 (1), 76-78, 2000 | 11 | 2000 |
Structure of the RWJ-51084–bovine pancreatic β-trypsin complex at 1.8 Ĺ R Recacha, M Carson, MJ Costanzo, B Maryanoff, LJ DeLucas, ... Acta Crystallographica Section D: Biological Crystallography 55 (11), 1785-1791, 1999 | 11 | 1999 |
Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions R Recacha, D Jiménez, L Tian, R Barredo, CG Gahmberg, ... Acta Crystallographica Section D: Biological Crystallography 70 (7), 1934-1943, 2014 | 9 | 2014 |
Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins R Recacha, K Jaudzems, I Akopjana, A Jirgensons, K Tars Acta Crystallographica Section F: Structural Biology Communications 72 (9 …, 2016 | 7 | 2016 |
Structure and supramolecular packing features of the dipeptide Arg‐Val acetate R Recacha, N Verdaguer, JA Subirana The Journal of peptide research 50 (5), 388-392, 1997 | 4 | 1997 |
Production of neutralizing antibody fragment variants in the cytoplasm of E. coli for rapid screening: SARS-CoV-2 a case study AA Tungekar, R Recacha, LW Ruddock Scientific Reports 13 (4408), 2023 | 2 | 2023 |
Efficient soluble production of folded cat allergen Fel d 1 in Escherichia coli C Zhang, R Recacha, L Ruddock, A Moilanen Protein Expression and Purification, 2020 | 2 | 2020 |
Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids N Anaganti, S Valmiki, R Recacha, S Islam, S Farber, L Ruddock, ... Journal of Biological Chemistry, 105726, 2024 | | 2024 |
Crystal structure of NK2-heparin complex R Recacha, B Mulloy, E Gherardi Acta Crystallographica Section A 67, C300-C300, 2011 | | 2011 |