Darren Tomlinson
Darren Tomlinson
Verified email at leeds.ac.uk - Homepage
Cited by
Cited by
FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma
AH Jebar, CD Hurst, DC Tomlinson, C Johnston, CF Taylor, MA Knowles
Oncogene 24 (33), 5218-5225, 2005
FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer
DC Tomlinson, O Baldo, P Harnden, MA Knowles
The Journal of pathology 213 (1), 91-98, 2007
Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo
FR Lamont, DC Tomlinson, PA Cooper, SD Shnyder, JD Chester, ...
British journal of cancer 104 (1), 75-82, 2011
Sonic hedgehog regulates prostatic growth and epithelial differentiation
SH Freestone, P Marker, OC Grace, DC Tomlinson, GR Cunha, ...
Developmental biology 264 (2), 352-362, 2003
An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
G Wheway, M Schmidts, DA Mans, K Szymanska, TMT Nguyen, H Racher, ...
Nature cell biology 17 (8), 1074-1087, 2015
Multidrug-resistant breast cancer: current perspectives
HL Martin, L Smith, DC Tomlinson
Breast Cancer: targets and therapy 6, 1, 2014
Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer
DC Tomlinson, CD Hurst, MA Knowles
Oncogene 26 (40), 5889-5899, 2007
Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer
DC Tomlinson, FR Lamont, SD Shnyder, MA Knowles
Cancer research 69 (11), 4613-4620, 2009
Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications
C Tiede, AAS Tang, SE Deacon, U Mandal, JE Nettleship, RL Owen, ...
Protein Engineering, Design and Selection 27 (5), 145-155, 2014
A decade of FGF receptor research in bladder cancer: past, present, and future challenges
E di Martino, DC Tomlinson, MA Knowles
Advances in urology 2012, 2012
Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification
CD Hurst, DC Tomlinson, SV Williams, FM Platt, MA Knowles
Oncogene 27 (19), 2716-2727, 2008
Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type-and mutation-specific manner
E Di Martino, CG L'hôte, W Kennedy, DC Tomlinson, MA Knowles
Oncogene 28 (48), 4306-4316, 2009
Affimer proteins are versatile and renewable affinity reagents
C Tiede, R Bedford, SJ Heseltine, G Smith, I Wijetunga, R Ross, ...
Elife 6, e24903, 2017
Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity
R Sharma, SE Deacon, D Nowak, SE George, MP Szymonik, AAS Tang, ...
Biosensors and Bioelectronics 80, 607-613, 2016
Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions
A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ...
Angewandte Chemie 127 (10), 3003-3008, 2015
FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms
DC Tomlinson, EW Baxter, PM Loadman, MA Hull, MA Knowles
PloS one 7 (6), e38972, 2012
Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor–induced proliferation and is repressed in …
DC Tomlinson, CG L'Hôte, W Kennedy, E Pitt, MA Knowles
Cancer research 65 (22), 10441-10449, 2005
Mechanisms of FGFR3 actions in endocrine resistant breast cancer
DC Tomlinson, MA Knowles, V Speirs
International journal of cancer 130 (12), 2857-2866, 2012
Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk
K Kearney, D Tomlinson, K Smith, R Ajjan
Cardiovascular Diabetology 16 (1), 34, 2017
High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers
HL Martin, M Adams, J Higgins, J Bond, EE Morrison, SM Bell, S Warriner, ...
PloS one 9 (2), e88338, 2014
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