|FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma|
AH Jebar, CD Hurst, DC Tomlinson, C Johnston, CF Taylor, MA Knowles
Oncogene 24 (33), 5218-5225, 2005
|FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer|
DC Tomlinson, O Baldo, P Harnden, MA Knowles
The Journal of pathology 213 (1), 91-98, 2007
|Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo|
FR Lamont, DC Tomlinson, PA Cooper, SD Shnyder, JD Chester, ...
British journal of cancer 104 (1), 75-82, 2011
|Sonic hedgehog regulates prostatic growth and epithelial differentiation|
SH Freestone, P Marker, OC Grace, DC Tomlinson, GR Cunha, ...
Developmental biology 264 (2), 352-362, 2003
|An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes|
G Wheway, M Schmidts, DA Mans, K Szymanska, TMT Nguyen, H Racher, ...
Nature cell biology 17 (8), 1074-1087, 2015
|Multidrug-resistant breast cancer: current perspectives|
HL Martin, L Smith, DC Tomlinson
Breast Cancer: targets and therapy 6, 1, 2014
|Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer|
DC Tomlinson, CD Hurst, MA Knowles
Oncogene 26 (40), 5889-5899, 2007
|Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer|
DC Tomlinson, FR Lamont, SD Shnyder, MA Knowles
Cancer research 69 (11), 4613-4620, 2009
|Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications|
C Tiede, AAS Tang, SE Deacon, U Mandal, JE Nettleship, RL Owen, ...
Protein Engineering, Design and Selection 27 (5), 145-155, 2014
|A decade of FGF receptor research in bladder cancer: past, present, and future challenges|
E di Martino, DC Tomlinson, MA Knowles
Advances in urology 2012, 2012
|Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification|
CD Hurst, DC Tomlinson, SV Williams, FM Platt, MA Knowles
Oncogene 27 (19), 2716-2727, 2008
|Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type-and mutation-specific manner|
E Di Martino, CG L'hôte, W Kennedy, DC Tomlinson, MA Knowles
Oncogene 28 (48), 4306-4316, 2009
|Affimer proteins are versatile and renewable affinity reagents|
C Tiede, R Bedford, SJ Heseltine, G Smith, I Wijetunga, R Ross, ...
Elife 6, e24903, 2017
|Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity|
R Sharma, SE Deacon, D Nowak, SE George, MP Szymonik, AAS Tang, ...
Biosensors and Bioelectronics 80, 607-613, 2016
|Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions|
A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ...
Angewandte Chemie 127 (10), 3003-3008, 2015
|FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms|
DC Tomlinson, EW Baxter, PM Loadman, MA Hull, MA Knowles
PloS one 7 (6), e38972, 2012
|Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor–induced proliferation and is repressed in …|
DC Tomlinson, CG L'Hôte, W Kennedy, E Pitt, MA Knowles
Cancer research 65 (22), 10441-10449, 2005
|Mechanisms of FGFR3 actions in endocrine resistant breast cancer|
DC Tomlinson, MA Knowles, V Speirs
International journal of cancer 130 (12), 2857-2866, 2012
|Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk|
K Kearney, D Tomlinson, K Smith, R Ajjan
Cardiovascular Diabetology 16 (1), 34, 2017
|High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers|
HL Martin, M Adams, J Higgins, J Bond, EE Morrison, SM Bell, S Warriner, ...
PloS one 9 (2), e88338, 2014