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Le Han (韩乐)
Le Han (韩乐)
VUIIS Vanderbilt Univ
Geverifieerd e-mailadres voor vumc.org
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A highly selective and sensitive fluorescence “turn-on” probe for Ag+ in aqueous solution and live cells
L Xu, Y Xu, W Zhu, C Yang, L Han, X Qian
Dalton Transactions 41 (24), 7212-7217, 2012
942012
Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts
GN Pandian, J Taniguchi, S Junetha, S Sato, L Han, A Saha, ...
Scientific reports 4 (1), 3843, 2014
702014
Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase
J Zhu, L Han, Y Diao, X Ren, M Xu, L Xu, S Li, Q Li, D Dong, J Huang, ...
Journal of Medicinal Chemistry 58 (3), 1123-1139, 2015
542015
Identification of a small molecule that turns ON the pluripotency gene circuitry in human fibroblasts
GN Pandian, S Sato, C Anandhakumar, J Taniguchi, K Takashima, J Syed, ...
ACS chemical biology 9 (12), 2729-2736, 2014
502014
Discovery of diverse human dihydroorotate dehydrogenase inhibitors as immunosuppressive agents by structure-based virtual screening
Y Diao, W Lu, H Jin, J Zhu, L Han, M Xu, R Gao, X Shen, Z Zhao, X Liu, ...
Journal of Medicinal Chemistry 55 (19), 8341-8349, 2012
502012
Rationally designed multitarget anticancer agents
Z Chen, L Han, M Xu, Y Xu, X Qian
Current medicinal chemistry 20 (13), 1694-1714, 2013
462013
A synthetic small molecule for targeted transcriptional activation of germ cell genes in a human somatic cell
L Han, GN Pandian, S Junetha, S Sato, C Anandhakumar, J Taniguchi, ...
Angew. Chem. Int. Ed 52, 13410-13413, 2013
442013
A synthetic DNA‐binding domain guides distinct chromatin‐modifying small molecules to activate an identical gene network
L Han, GN Pandian, A Chandran, S Sato, J Taniguchi, G Kashiwazaki, ...
Angewandte Chemie 127 (30), 8824-8827, 2015
412015
Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts. Sci Rep 4: 3843
GN Pandian, J Taniguchi, S Junetha, S Sato, L Han, A Saha, ...
22014
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Artikelen 1–9