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JJ Worthington
JJ Worthington
Verified email at lancaster.ac.uk - Homepage
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Year
TGFβ: a sleeping giant awoken by integrins
JJ Worthington, JE Klementowicz, MA Travis
Trends in biochemical sciences 36 (1), 47-54, 2011
2842011
Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity
JJ Worthington, F Reimann, FM Gribble
Mucosal immunology 11 (1), 3-20, 2018
2472018
Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance.
RIS Houlden A, Hayes KS, Bancroft AJ, Worthington JJ, Wang P, Grencis RK
Plos One 10 (5), e0125945, 2015
2102015
Intestinal dendritic cells specialize to activate transforming growth factor-β and induce Foxp3+ regulatory T cells via integrin αvβ8
JJ Worthington, BI Czajkowska, AC Melton, MA Travis
Gastroenterology 141 (5), 1802-1812, 2011
2022011
Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation.
JJ Worthington, A Kelly, C Smedley, D Bauché, S Campbell, JC Marie, ...
Immunity 42 (5), 903-915, 2015
1962015
Nesfatin-1, a unique regulatory neuropeptide of the brain
A Pałasz, M Krzystanek, J Worthington, B Czajkowska, K Kostro, ...
Neuropeptides 46 (3), 105-112, 2012
1452012
Regulation of TGFβ in the immune system: an emerging role for integrins and dendritic cells
JJ Worthington, TM Fenton, BI Czajkowska, JE Klementowicz, MA Travis
Immunobiology 217 (12), 1259-1265, 2012
1362012
Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders?
GW Moran, FC Leslie, SE Levison, JJ Worthington, JT McLaughlin
Therapeutic advances in gastroenterology 1 (1), 51-60, 2008
1282008
The intestinal immunoendocrine axis-novel cross talk between enteroendocrine cells and the immune system during infection and inflammatory disease.
JJ Worthington
Biochemical Society Transactions 43 (4), 727–733, 2015
1232015
WSX-1: a key role in induction of chronic intestinal nematode infection
AJ Bancroft, NE Humphreys, JJ Worthington, H Yoshida, RK Grencis
The Journal of Immunology 172 (12), 7635-7641, 2004
772004
Molecular Characterization and Expression of Urotensin II and its Receptor in the Flounder (Platichthys flesus): A Hormone System Supporting Body Fluid …
W Lu, M Greenwood, L Dow, J Yuill, J Worthington, MJ Brierley, ...
Endocrinology 147 (8), 3692-3708, 2006
692006
Trichinella spiralis antigens prime mixed Th1/Th2 response but do not induce de novo generation of Foxp3+ T cells in vitro
N Ilic, JJ Worthington, A Gruden‐Movsesijan, MA Travis, ...
Parasite Immunology 33 (10), 572-582, 2011
682011
Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8
TM Fenton, A Kelly, EE Shuttleworth, C Smedley, A Atakilit, F Powrie, ...
Mucosal immunology 10 (3), 624-634, 2017
672017
The novel neuropeptide phoenixin is highly co-expressed with nesfatin-1 in the rat hypothalamus, an immunohistochemical study
RW Artur Pałasza, Ewa Rojczyka, Katarzyna Bogusa, John J. Worthington
Neuroscience Letters 592, 17-21, 2015
632015
The potential role of the novel hypothalamic neuropeptides nesfatin-1, phoenixin, spexin and kisspeptin in the pathogenesis of anxiety and anorexia nervosa
A Pałasz, M Janas-Kozik, A Borrow, O Arias-Carrión, JJ Worthington
Neurochemistry international 113, 120-136, 2018
562018
Tuft cells: a new flavor in innate epithelial immunity
RK Grencis, JJ Worthington
Trends in parasitology 32 (8), 583-585, 2016
482016
Adaptive immunity alters distinct host feeding pathways during nematode induced inflammation, a novel mechanism in parasite expulsion
JJ Worthington, LC Samuelson, RK Grencis, JT McLaughlin
PLoS Pathogens 9 (1), e1003122, 2013
482013
Loss of the TGFβ-activating integrin αvβ8 on dendritic cells protects mice from chronic intestinal parasitic infection via control of type 2 immunity
JJ Worthington, JE Klementowicz, S Rahman, BI Czajkowska, C Smedley, ...
PLoS pathogens 9 (10), e1003675, 2013
452013
Seasonal changes in peptide, receptor and ion channel mRNA expression in the caudal neurosecretory system of the European flounder (Platichthys flesus)
W Lu, J Worthington, D Riccardi, RJ Balment, CR McCrohan
General and comparative endocrinology 153 (1-3), 262-272, 2007
382007
Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2
JG Park, FS Oladunni, MA Rohaim, J Whittingham-Dowd, J Tollitt, ...
IScience 24 (9), 2021
372021
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