Reducing codon redundancy and screening effort of combinatorial protein libraries created by saturation mutagenesis S Kille, CG Acevedo-Rocha, LP Parra, ZG Zhang, DJ Opperman, ... ACS synthetic biology 2 (2), 83-92, 2013 | 364 | 2013 |
Discovery, molecular mechanisms, and industrial applications of cold-active enzymes M Santiago, CA Ramírez-Sarmiento, RA Zamora, LP Parra Frontiers in microbiology 7, 222937, 2016 | 260 | 2016 |
Active site flexibility as a hallmark for efficient PET degradation by I. sakaiensis PETase T Fecker, P Galaz-Davison, F Engelberger, Y Narui, M Sotomayor, ... Biophysical journal 114 (6), 1302-1312, 2018 | 243 | 2018 |
Protein engineering for nicotinamide coenzyme specificity in oxidoreductases: attempts and challenges AM Chánique, LP Parra Frontiers in microbiology 9, 325410, 2018 | 67 | 2018 |
Protein engineering of stereoselective Baeyer–Villiger monooxygenases ZG Zhang, LP Parra, MT Reetz Chemistry–A European Journal 18 (33), 10160-10172, 2012 | 64 | 2012 |
Directed evolution by using iterative saturation mutagenesis based on multiresidue sites LP Parra, R Agudo, MT Reetz ChemBioChem 14 (17), 2301-2309, 2013 | 59 | 2013 |
Cloning and fusion expression of a cold-active lipase from marine Antarctic origin LP Parra, F Reyes, JP Acevedo, O Salazar, BA Andrews, JA Asenjo Enzyme and Microbial Technology 42 (4), 371-377, 2008 | 58 | 2008 |
Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique JP Acevedo, F Reyes, LP Parra, O Salazar, BA Andrews, JA Asenjo Journal of biotechnology 133 (3), 277-286, 2008 | 54 | 2008 |
One-step combined focused epPCR and saturation mutagenesis for thermostability evolution of a new cold-active xylanase JP Acevedo, MT Reetz, JA Asenjo, LP Parra Enzyme and microbial technology 100, 60-70, 2017 | 45 | 2017 |
Directed evolution of phenylacetone monooxygenase as an active catalyst for the Baeyer–Villiger conversion of cyclohexanone to caprolactone LP Parra, JP Acevedo, MT Reetz Biotechnology and Bioengineering 112 (7), 1354-1364, 2015 | 39 | 2015 |
Identification of lipase encoding genes from Antarctic seawater bacteria using degenerate primers: expression of a cold-active lipase with high specific activity LP Parra, G Espina, J Devia, O Salazar, B Andrews, JA Asenjo Enzyme and microbial technology 68, 56-61, 2015 | 25 | 2015 |
Relevance of local flexibility near the active site for enzymatic catalysis: biochemical characterization and engineering of cellulase Cel5A from Bacillus agaradherans JM Saavedra, MA Azócar, V Rodríguez, CA Ramírez‐Sarmiento, ... Biotechnology Journal 13 (8), 1700669, 2018 | 24 | 2018 |
Systematic assessment of uncoupling in flavoprotein oxidases and monooxygenases A Gran-Scheuch, L Parra, MW Fraaije ACS Sustainable Chemistry & Engineering 11 (13), 4948-4959, 2021 | 20 | 2021 |
Surfing the blood coagulation cascade: insight into the vital factor Xa NE Núñez-Navarro, FM Santana, LP Parra, FC Zacconi Current Medicinal Chemistry 26 (17), 3175-3200, 2019 | 20 | 2019 |
Mining the Genome of Streptomyces leeuwenhoekii: Two New Type I Baeyer–Villiger Monooxygenases From Atacama Desert A Gran-Scheuch, M Trajkovic, L Parra, MW Fraaije Frontiers in microbiology 9, 354532, 2018 | 20 | 2018 |
Rational Design of Resveratrol O-methyltransferase for the Production of Pinostilbene DP Herrera, AM Chánique, A Martínez-Márquez, R Bru-Martínez, ... International Journal of Molecular Sciences 22 (9), 4345, 2021 | 13 | 2021 |
A Structural View on the Stereospecificity of Plant Borneol‐Type Dehydrogenases AM Chánique, N Dimos, I Drienovská, E Calderini, MP Pantín, ... ChemCatChem 13 (9), 2262-2277, 2021 | 10 | 2021 |
Protein and DNA sequence encoding a cold adapted xylanase JA Asenjo, BA Andrews, JP Acevedo, L Parra, LO Burzio US Patent 8,679,814, 2014 | 6 | 2014 |
A Cold-Active Flavin-Dependent Monooxygenase from Janthinobacterium svalbardensis Unlocks Applications of Baeyer–Villiger Monooxygenases at Low … AM Chánique, N Polidori, L Sovic, D Kracher, L Assil-Companioni, ... ACS catalysis 13 (6), 3549-3562, 2023 | 3 | 2023 |
Discovery of new phenylacetone monooxygenase variants for the development of substituted indigoids through biocatalysis N Núñez-Navarro, J Salazar Muñoz, F Castillo, CA Ramírez-Sarmiento, ... International Journal of Molecular Sciences 23 (20), 12544, 2022 | 3 | 2022 |