Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis U Barash, V Cohen‐Kaplan, I Dowek, RD Sanderson, N Ilan, I Vlodavsky The FEBS journal 277 (19), 3890-3903, 2010 | 210 | 2010 |
Binding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shock G Arad, R Levy, I Nasie, D Hillman, Z Rotfogel, U Barash, E Supper, ... PLoS biology 9 (9), e1001149, 2011 | 170 | 2011 |
Heparanase enhances myeloma progression via CXCL10 downregulation U Barash, Y Zohar, G Wildbaum, K Beider, A Nagler, N Karin, N Ilan, ... Leukemia 28 (11), 2178-2187, 2014 | 96 | 2014 |
Targeting heparanase in cancer: inhibition by synthetic, chemically modified, and natural compounds CD Mohan, S Hari, HD Preetham, S Rangappa, U Barash, N Ilan, ... Iscience 15, 360-390, 2019 | 75 | 2019 |
Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis I Boyango, U Barash, I Naroditsky, JP Li, E Hammond, N Ilan, I Vlodavsky Cancer research 74 (16), 4504-4514, 2014 | 74 | 2014 |
Specific inhibition of heparanase by a glycopolymer with well-defined sulfation pattern prevents breast cancer metastasis in mice RS Loka, ET Sletten, U Barash, I Vlodavsky, HM Nguyen ACS applied materials & interfaces 11 (1), 244-254, 2018 | 54 | 2018 |
Identification of novel class of triazolo-thiadiazoles as potent inhibitors of human heparanase and their anticancer activity CP Baburajeev, CD Mohan, S Rangappa, DJ Mason, JE Fuchs, A Bender, ... BMC cancer 17, 1-14, 2017 | 49 | 2017 |
Involvement of heparanase in the pathogenesis of mesothelioma: basic aspects and clinical applications U Barash, M Lapidot, Y Zohar, C Loomis, A Moreira, S Feld, C Goparaju, ... JNCI: Journal of the National Cancer Institute 110 (10), 1102-1114, 2018 | 46 | 2018 |
A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics U Barash, V Cohen-Kaplan, G Arvatz, S Gingis-Velitski, F Levy-Adam, ... The FASEB Journal 24 (4), 1239, 2010 | 46 | 2010 |
Heparanase 2 attenuates head and neck tumor vascularity and growth M Gross-Cohen, S Feld, I Doweck, G Neufeld, P Hasson, G Arvatz, ... Cancer research 76 (9), 2791-2801, 2016 | 42 | 2016 |
Post-transcriptional regulation of heparanase gene expression by a 3′ AU-rich element G Arvatz, U Barash, O Nativ, N Ilan, I Vlodavsky The FASEB Journal 24 (12), 4969, 2010 | 41 | 2010 |
Heparanase promotes glioma progression via enhancing CD24 expression U Barash, A Spyrou, P Liu, E Vlodavsky, C Zhu, J Luo, D Su, N Ilan, ... International journal of cancer 145 (6), 1596-1608, 2019 | 40 | 2019 |
Targeting heparanase to the mammary epithelium enhances mammary gland development and promotes tumor growth and metastasis I Boyango, U Barash, L Fux, I Naroditsky, N Ilan, I Vlodavsky Matrix Biology 65, 91-103, 2018 | 38 | 2018 |
Heparanase and chemotherapy synergize to drive macrophage activation and enhance tumor growth U Bhattacharya, L Gutter-Kapon, T Kan, I Boyango, U Barash, SM Yang, ... Cancer research 80 (1), 57-68, 2020 | 36 | 2020 |
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth A Spyrou, S Kundu, L Haseeb, D Yu, T Olofsson, K Dredge, E Hammond, ... Molecular Cancer Therapeutics 16 (8), 1705-1716, 2017 | 36 | 2017 |
Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo C de Boer, Z Armstrong, VAJ Lit, U Barash, G Ruijgrok, I Boyango, ... Proceedings of the National Academy of Sciences 119 (31), e2203167119, 2022 | 27 | 2022 |
The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis L Koren, U Barash, Y Zohar, N Karin, A Aronheim International journal of cardiology 228, 394-400, 2017 | 26 | 2017 |
Glycosaminoglycans as tools to decipher the platelet tumor cell interaction: a focus on P-selectin S Schwarz, LM Gockel, A Naggi, U Barash, M Gobec, G Bendas, ... Molecules 25 (5), 1039, 2020 | 25 | 2020 |
Basappa; Vlodavsky, I.; et al CD Mohan, S Hari, HD Preetham, S Rangappa, U Barash, N Ilan, ... Targeting heparanase in cancer: Inhibition by synthetic, chemically modified …, 2019 | 24 | 2019 |
Biology of the heparanase–heparan sulfate axis and its role in disease pathogenesis I Vlodavsky, U Barash, HM Nguyen, SM Yang, N Ilan Seminars in thrombosis and hemostasis 47 (03), 240-253, 2021 | 22 | 2021 |