Creation of human tumour cells with defined genetic elements WC Hahn, CM Counter, AS Lundberg, RL Beijersbergen, MW Brooks, ... Nature 400 (6743), 464-468, 1999 | 3070 | 1999 |
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. CM Counter, AA Avilion, CE LeFeuvre, NG Stewart, CW Greider, ... The EMBO journal 11 (5), 1921-1929, 1992 | 2891 | 1992 |
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization M Meyerson, CM Counter, EN Eaton, LW Ellisen, P Steiner, SD Caddle, ... cell 90 (4), 785-795, 1997 | 2589 | 1997 |
Telomerase activity in normal leukocytes and in hematologic malignancies CM Counter, J Gupta, CB Harley, B Leber, S Bacchetti | 1168 | 1995 |
Telomerase activity in human ovarian carcinoma. CM Counter, HW Hirte, S Bacchetti, CB Harley Proceedings of the National Academy of Sciences 91 (8), 2900-2904, 1994 | 1047 | 1994 |
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells E Yeh, M Cunningham, H Arnold, D Chasse, T Monteith, G Ivaldi, ... Nature cell biology 6 (4), 308-318, 2004 | 939 | 2004 |
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization CM Counter, WC Hahn, W Wei, SD Caddle, RL Beijersbergen, ... Proceedings of the National Academy of Sciences 95 (25), 14723-14728, 1998 | 833 | 1998 |
The telomere hypothesis of cellular aging CB Harley, H Vaziri, CM Counter, RC Allsopp Experimental gerontology 27 (4), 375-382, 1992 | 690 | 1992 |
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase CM Counter, M Meyerson, EN Eaton, LW Ellisen, SD Caddle, DA Haber, ... Oncogene 16 (9), 1217-1222, 1998 | 632 | 1998 |
Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth JA Kashatus, A Nascimento, LJ Myers, A Sher, FL Byrne, KL Hoehn, ... Molecular cell 57 (3), 537-551, 2015 | 605 | 2015 |
Distinct requirements for Ras oncogenesis in human versus mouse cells NM Hamad, JH Elconin, AE Karnoub, W Bai, JN Rich, RT Abraham, ... Genes & development 16 (16), 2045-2057, 2002 | 541 | 2002 |
Telomerase, cell immortality, and cancer CB Harley, NW Kim, KR Prowse, SL Weinrich, KS Hirsch, MD West, ... Cold Spring Harbor symposia on quantitative biology 59, 307-315, 1994 | 539 | 1994 |
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues KA Kolquist, LW Ellisen, CM Counter, MM Meyerson, LK Tan, ... Nature genetics 19 (2), 182-186, 1998 | 524 | 1998 |
Copper is required for oncogenic BRAF signalling and tumorigenesis DC Brady, MS Crowe, ML Turski, GA Hobbs, X Yao, A Chaikuad, S Knapp, ... Nature 509 (7501), 492-496, 2014 | 509 | 2014 |
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis B Ancrile, KH Lim, CM Counter Genes & development 21 (14), 1714-1719, 2007 | 489 | 2007 |
Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression S Shi, S Gronthos, S Chen, A Reddi, CM Counter, PG Robey, CY Wang Nature biotechnology 20 (6), 587-591, 2002 | 484 | 2002 |
Stabilization of short telomeres and telomerase activity accompany immortalization of Epstein-Barr virus-transformed human B lymphocytes CM Counter, FM Botelho, P Wang, CB Harley, S Bacchetti Journal of virology 68 (5), 3410-3414, 1994 | 469 | 1994 |
Activation of RalA is critical for Ras-induced tumorigenesis of human cells KH Lim, AT Baines, JJ Fiordalisi, M Shipitsin, LA Feig, AD Cox, CJ Der, ... Cancer cell 7 (6), 533-545, 2005 | 439 | 2005 |
RALA and RALBP1 regulate mitochondrial fission at mitosis DF Kashatus, KH Lim, DC Brady, NLK Pershing, AD Cox, CM Counter Nature cell biology 13 (9), 1108-1115, 2011 | 381 | 2011 |
Tumour maintenance is mediated by eNOS KH Lim, BB Ancrile, DF Kashatus, CM Counter Nature 452 (7187), 646-649, 2008 | 359 | 2008 |