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Pamela A G Clarke  Clarke
Pamela A G Clarke Clarke
Adresse e-mail validée de georgetown.edu
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Hydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer
KL Cook, A Wärri, DR Soto-Pantoja, PAG Clarke, MI Cruz, A Zwart, ...
Clinical Cancer Research 20 (12), 3222-3232, 2014
2232014
Endoplasmic reticulum stress protein GRP78 modulates lipid metabolism to control drug sensitivity and antitumor immunity in breast cancer
KL Cook, DR Soto-Pantoja, PAG Clarke, MI Cruz, A Zwart, A Wärri, ...
Cancer research 76 (19), 5657-5670, 2016
1062016
Knockdown of estrogen receptor-α induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation, promoting ROS-induced breast cancer cell death
KL Cook, PAG Clarke, J Parmar, R Hu, JL Schwartz-Roberts, M Abu-Asab, ...
The FASEB Journal 28 (9), 3891-3905, 2014
912014
Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy
KL Cook, DR Soto-Pantoja, M Abu-Asab, PA Clarke, DD Roberts, ...
Cell Biosci 4 (1), 16, 2014
742014
Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy
DDRRC Katherine L Cook1, David R Soto-Pantoja2, Mones Abu-Asab3, Pamela AG ...
Cell & Bioscience 4 (16), 9, 2014
74*2014
Targeting GRP78 and antiestrogen resistance in breast cancer
KL Cook, PAG Clarke, R Clarke
Future medicinal chemistry 5 (9), 1047-1057, 2013
382013
Modelling the effect of GRP78 on anti-oestrogen sensitivity and resistance in breast cancer
JH Parmar, KL Cook, AN Shajahan-Haq, PAG Clarke, I Tavassoly, ...
Interface focus 3 (4), 20130012, 2013
332013
Heterozygous ATG7 inhibition enhances endocrine therapy responsiveness through regulation of damage associated molecular patterns and priming the immune system in ER+ breast tumors
R Clarke, PAG Clarke, A Wärri, KL Cook
Cancer Research 76 (14_Supplement), 904-904, 2016
2016
INHIBITING AUTOPHAGY AS A STRATEGY TO IMPROVE ANTIESTROGEN RESPONSES IN BREAST CANCER
K Cook, A Waerri, D Soto-Pantoja, P Clarke, I Cruz, A Zwart, R Clarke
ANTICANCER RESEARCH 34 (10), 5868-5869, 2014
2014
Novel role of glucose-regulated protein 78 mediating lipid metabolism through controlling stearoyl-CoA desaturase 1
KL Cook, PAG Clarke, M Axelrod, A Wärri, R Clarke
Cancer Research 74 (19 Supplement), 2443-2443, 2014
2014
Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1
K Cook, P Clarke, A Warri, R Clarke
Cancer & metabolism 2 (1), 1-1, 2014
2014
Estrogen receptor-α (ER) integration of unfolded protein response signaling activates autophagy and production of reactive oxygen species to determine ER+ breast cancer cell fate
R Clarke, P Clarke, R Hu, M Abu-Asab, AM Warri, KL Cook
Breast & Prostate Cancer, SAT-317-SAT-317, 2013
2013
Estrogen receptor-α coordinates the unfolded protein response, autophagy, and reactive oxygen species generation to regulate breast cancer survival.
PA Clarke, K Cook, R Hu, JL Schwartz, M Abu-Asab, A Warri, R Clarke
Cancer Research 73 (8 Supplement), 4046-4046, 2013
2013
Knockdown of estrogen receptor-induces autophagy and inhibits antiestrogen-mediated unfolded protein response activation promoting ROS-induced breast cancer cell death
KL Cook, PAG Clarke, J Parmar, R Hu, JL Schwartz-Roberts, M Abu-Asab, ...
SAT-317: Estrogen receptor-α (ER) integration of unfolded protein response signaling activates autophagy and production of reactive oxygen species to determine ER+ breast …
R Clarke, P Clarke, R Hu, M Abu-Asab, AM Warri, KL Cook
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