| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 569 | 2020 |
| Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short‐chain dehydrogenase/reductase fold without an NAD (P) H binding site RM de Jong, JJW Tiesinga, HJ Rozeboom, KH Kalk, L Tang, DB Janssen, ... The EMBO journal 22 (19), 4933-4944, 2003 | 162 | 2003 |
| Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene J Beekwilder, A van Houwelingen, K Cankar, ADJ van Dijk, RM de Jong, ... Plant biotechnology journal 12 (2), 174-182, 2014 | 133 | 2014 |
| Engineering of an endogenous hexose transporter into a specific D-xylose transporter facilitates glucose-xylose co-consumption in Saccharomyces cerevisiae JG Nijland, HY Shin, RM de Jong, PP De Waal, P Klaassen, ... Biotechnology for biofuels 7 (1), 1-11, 2014 | 129 | 2014 |
| Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon–halogen bond RM de Jong, BW Dijkstra Current opinion in structural biology 13 (6), 722-730, 2003 | 125 | 2003 |
| Modified chymosin polypeptides PJT Dekker, RM De Jong, MD Tabeling, CM Muijlwijk US Patent 10,167,463, 2019 | 122* | 2019 |
| Carbohydrate degrading polypeptide and uses thereof AP Los, RM De Jong, M APPELDOORN US Patent 10,316,305, 2019 | 103* | 2019 |
| Coupling protein side-chain and backbone flexibility improves the re-design of protein-ligand specificity N Ollikainen, RM de Jong, T Kortemme PLoS computational biology 11 (9), e1004335, 2015 | 88 | 2015 |
| Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC RM de Jong, JJW Tiesinga, A Villa, L Tang, DB Janssen, BW Dijkstra Journal of the American Chemical Society 127 (38), 13338-13343, 2005 | 86 | 2005 |
| An engineered cryptic Hxt11 sugar transporter facilitates glucose–xylose co-consumption in Saccharomyces cerevisiae HY Shin, JG Nijland, PP de Waal, RM de Jong, P Klaassen, AJM Driessen Biotechnology for biofuels 8 (1), 176, 2015 | 72 | 2015 |
| Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site L Tang, DE Torres Pazmiño, MW Fraaije, RM De Jong, BW Dijkstra, ... Biochemistry 44 (17), 6609-6618, 2005 | 70 | 2005 |
| Valencene oxidase CYP706M1 from Alaska cedar (Callitropsis nootkatensis) K Cankar, A van Houwelingen, M Goedbloed, R Renirie, RM de Jong, ... FEBS letters 588 (6), 1001-1007, 2014 | 64 | 2014 |
| Pentose sugar fermenting cell P Klaassen, GP Van Suylekom, RM De Jong US Patent 10,100,320, 2018 | 61* | 2018 |
| The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily RM de Jong, W Brugman, GJ Poelarends, CP Whitman, BW Dijkstra Journal of Biological Chemistry 279 (12), 11546-11552, 2004 | 56 | 2004 |
| The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family RM de Jong, KH Kalk, L Tang, DB Janssen, BW Dijkstra Journal of bacteriology 188 (11), 4051-4056, 2006 | 45 | 2006 |
| Cells with improved pentose conversion MBE Jonkers, P Klaassen, AWRH Teunissen, RM De Jong US Patent App. 10/273,507, 2019 | 40* | 2019 |
| Metal Dependence of the Xylose Isomerase from Piromyces sp. E2 Explored by Activity Profiling and Protein Crystallography M Lee, HJ Rozeboom, PP de Waal, RM de Jong, HM Dudek, DB Janssen Biochemistry 56 (45), 5991-6005, 2017 | 39 | 2017 |
| Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate RM de Jong, P Bazzacco, GJ Poelarends, WH Johnson, YJ Kim, EA Burks, ... Journal of Biological Chemistry 282 (4), 2440-2449, 2007 | 39 | 2007 |
| Escherichia coli MltA: MAD phasing and refinement of a tetartohedrally twinned protein crystal structure TRM Barends, RM De Jong, KE Van Straaten, AMWH Thunnissen, ... Acta Crystallographica Section D: Biological Crystallography 61 (5), 613-621, 2005 | 35 | 2005 |
| Alpha-amylase variants RM De Jong, HE ABBAS, ET Van Rij US Patent App. 10/327,449, 2019 | 29* | 2019 |
