Susan Tsutakawa
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Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
GL Hura, AL Menon, M Hammel, RP Rambo, FL Poole Ii, SE Tsutakawa, ...
Nature methods 6 (8), 606-612, 2009
Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily
SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ...
Cell 145 (2), 198-211, 2011
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome
AH Sarker, SE Tsutakawa, S Kostek, C Ng, DS Shin, M Peris, E Campeau, ...
Molecular cell 20 (2), 187-198, 2005
Exploring the repeat protein universe through computational protein design
TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ...
Nature 528 (7583), 580-584, 2015
Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN
J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ...
Molecular cell 64 (4), 688-703, 2016
High-throughput SAXS for the characterization of biomolecules in solution: a practical approach
KN Dyer, M Hammel, RP Rambo, SE Tsutakawa, I Rodic, S Classen, ...
Structural Genomics, 245-258, 2014
Determination of in vivo phosphorylation sites in protein kinase C
SE Tsutakawa, KF Medzihradszky, AJ Flint, AL Burlingame, DE Koshland
Journal of Biological Chemistry 270 (45), 26807-26812, 1995
Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex
SE Tsutakawa, H Jingami, K Morikawa
Cell 99 (6), 615-623, 1999
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography
SE Tsutakawa, GL Hura, KA Frankel, PK Cooper, JA Tainer
Journal of structural biology 158 (2), 214-223, 2007
The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once
SE Tsutakawa, J Lafrance-Vanasse, JA Tainer
DNA repair 19, 95-107, 2014
A new structural framework for integrating replication protein A into DNA processing machinery
CA Brosey, C Yan, SE Tsutakawa, WT Heller, RP Rambo, JA Tainer, ...
Nucleic acids research 41 (4), 2313-2327, 2013
The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system
NG Lintner, KA Frankel, SE Tsutakawa, DL Alsbury, V Copiť, MJ Young, ...
Journal of molecular biology 405 (4), 939-955, 2011
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes
SE Tsutakawa, DS Shin, CD Mol, T Izumi, AS Arvai, AK Mantha, ...
Journal of Biological Chemistry 288 (12), 8445-8455, 2013
Crystallographic and functional studies of very short patch repair endonuclease
SE Tsutakawa, T Muto, T Kawate, H Jingami, N Kunishima, M Ariyoshi, ...
Molecular cell 3 (5), 621-628, 1999
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA
SE Tsutakawa, AW Van Wynsberghe, BD Freudenthal, CP Weinacht, ...
Proceedings of the National Academy of Sciences 108 (43), 17672-17677, 2011
Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp2
K Shi, K Kurahashi, R Gao, SE Tsutakawa, JA Tainer, Y Pommier, ...
Nature structural & molecular biology 19 (12), 1372-1377, 2012
Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases
JA Grasby, LD Finger, SE Tsutakawa, JM Atack, JA Tainer
Trends in biochemical sciences 37 (2), 74-84, 2012
Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability
SE Tsutakawa, MJ Thompson, AS Arvai, AJ Neil, SJ Shaw, SI Algasaier, ...
Nature communications 8 (1), 1-15, 2017
Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends
N Patel, JM Atack, LD Finger, JC Exell, P Thompson, S Tsutakawa, ...
Nucleic acids research 40 (10), 4507-4519, 2012
The wonders of flap endonucleases: structure, function, mechanism and regulation
LD Finger, JM Atack, S Tsutakawa, S Classen, J Tainer, J Grasby, B Shen
The eukaryotic replisome: a guide to protein structure and function, 301-326, 2012
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