|Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)|
GL Hura, AL Menon, M Hammel, RP Rambo, FL Poole Ii, SE Tsutakawa, ...
Nature methods 6 (8), 606-612, 2009
|Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily|
SE Tsutakawa, S Classen, BR Chapados, AS Arvai, LD Finger, ...
Cell 145 (2), 198-211, 2011
|Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome|
AH Sarker, SE Tsutakawa, S Kostek, C Ng, DS Shin, M Peris, E Campeau, ...
Molecular cell 20 (2), 187-198, 2005
|Exploring the repeat protein universe through computational protein design|
TJ Brunette, F Parmeggiani, PS Huang, G Bhabha, DC Ekiert, ...
Nature 528 (7583), 580-584, 2015
|Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN|
J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ...
Molecular cell 64 (4), 688-703, 2016
|High-throughput SAXS for the characterization of biomolecules in solution: a practical approach|
KN Dyer, M Hammel, RP Rambo, SE Tsutakawa, I Rodic, S Classen, ...
Structural Genomics, 245-258, 2014
|Determination of in vivo phosphorylation sites in protein kinase C|
SE Tsutakawa, KF Medzihradszky, AJ Flint, AL Burlingame, DE Koshland
Journal of Biological Chemistry 270 (45), 26807-26812, 1995
|Recognition of a TG mismatch: the crystal structure of very short patch repair endonuclease in complex with a DNA duplex|
SE Tsutakawa, H Jingami, K Morikawa
Cell 99 (6), 615-623, 1999
|Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography|
SE Tsutakawa, GL Hura, KA Frankel, PK Cooper, JA Tainer
Journal of structural biology 158 (2), 214-223, 2007
|The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once|
SE Tsutakawa, J Lafrance-Vanasse, JA Tainer
DNA repair 19, 95-107, 2014
|A new structural framework for integrating replication protein A into DNA processing machinery|
CA Brosey, C Yan, SE Tsutakawa, WT Heller, RP Rambo, JA Tainer, ...
Nucleic acids research 41 (4), 2313-2327, 2013
|The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system|
NG Lintner, KA Frankel, SE Tsutakawa, DL Alsbury, V Copiť, MJ Young, ...
Journal of molecular biology 405 (4), 939-955, 2011
|Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes|
SE Tsutakawa, DS Shin, CD Mol, T Izumi, AS Arvai, AK Mantha, ...
Journal of Biological Chemistry 288 (12), 8445-8455, 2013
|Crystallographic and functional studies of very short patch repair endonuclease|
SE Tsutakawa, T Muto, T Kawate, H Jingami, N Kunishima, M Ariyoshi, ...
Molecular cell 3 (5), 621-628, 1999
|Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA|
SE Tsutakawa, AW Van Wynsberghe, BD Freudenthal, CP Weinacht, ...
Proceedings of the National Academy of Sciences 108 (43), 17672-17677, 2011
|Structural basis for recognition of 5′-phosphotyrosine adducts by Tdp2|
K Shi, K Kurahashi, R Gao, SE Tsutakawa, JA Tainer, Y Pommier, ...
Nature structural & molecular biology 19 (12), 1372-1377, 2012
|Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases|
JA Grasby, LD Finger, SE Tsutakawa, JM Atack, JA Tainer
Trends in biochemical sciences 37 (2), 74-84, 2012
|Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability|
SE Tsutakawa, MJ Thompson, AS Arvai, AJ Neil, SJ Shaw, SI Algasaier, ...
Nature communications 8 (1), 1-15, 2017
|Flap endonucleases pass 5′-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5′-ends|
N Patel, JM Atack, LD Finger, JC Exell, P Thompson, S Tsutakawa, ...
Nucleic acids research 40 (10), 4507-4519, 2012
|The wonders of flap endonucleases: structure, function, mechanism and regulation|
LD Finger, JM Atack, S Tsutakawa, S Classen, J Tainer, J Grasby, B Shen
The eukaryotic replisome: a guide to protein structure and function, 301-326, 2012