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Graeme Cottrell
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Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
G Barbara, V Stanghellini, R De Giorgio, C Cremon, GS Cottrell, D Santini, ...
Gastroenterology 126 (3), 693-702, 2004
17542004
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
M Trevisani, J Siemens, S Materazzi, DM Bautista, R Nassini, B Campi, ...
Proceedings of the National Academy of Sciences 104 (33), 13519-13524, 2007
8552007
Role for protease activity in visceral pain in irritable bowel syndrome
N Cenac, CN Andrews, M Holzhausen, K Chapman, G Cottrell, ...
Journal of Clinical Investigation 117 (3), 636-647, 2007
6882007
Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
S Amadesi, J Nie, N Vergnolle, GS Cottrell, EF Grady, M Trevisani, ...
The Journal of neuroscience 24 (18), 4300-4312, 2004
4762004
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
AD Grant, GS Cottrell, S Amadesi, M Trevisani, P Nicoletti, S Materazzi, ...
The Journal of physiology 578 (3), 715-733, 2007
4222007
Endosomes: a legitimate platform for the signaling train
JE Murphy, BE Padilla, B Hasdemir, GS Cottrell, NW Bunnett
Proceedings of the National Academy of Sciences 106 (42), 17615-17622, 2009
4122009
Mast Cell Tryptase Controls Paracellular Permeability of the Intestine ROLE OF PROTEASE-ACTIVATED RECEPTOR 2 AND β-ARRESTINS
C Jacob, PC Yang, D Darmoul, S Amadesi, T Saito, GS Cottrell, ...
Journal of Biological Chemistry 280 (36), 31936-31948, 2005
4092005
The TGR5 receptor mediates bile acid–induced itch and analgesia
F Alemi, E Kwon, DP Poole, TM Lieu, V Lyo, F Cattaruzza, F Cevikbas, ...
The Journal of clinical investigation 123 (4), 1513, 2013
3892013
Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐and A‐dependent mechanisms in rats and mice
S Amadesi, GS Cottrell, L Divino, K Chapman, EF Grady, F Bautista, ...
The Journal of physiology 575 (2), 555-571, 2006
3172006
Proteinase-activated receptors, targets for kallikrein signaling
K Oikonomopoulou, KK Hansen, M Saifeddine, I Tea, M Blaber, SI Blaber, ...
Journal of Biological Chemistry 281 (43), 32095-32112, 2006
2862006
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system
DP Poole, C Godfrey, F Cattaruzza, GS Cottrell, JG Kirkland, JC Pelayo, ...
Neurogastroenterology & Motility 22 (7), 814-e228, 2010
2352010
Mast cell tryptase and proteinase‐activated receptor 2 induce hyperexcitability of guinea‐pig submucosal neurons
DE Reed, C Barajas‐Lopez, G Cottrell, S Velazquez‐Rocha, O Dery, ...
The Journal of physiology 547 (2), 531-542, 2003
2082003
Trypsin IV, a novel agonist of protease-activated receptors 2 and 4
GS Cottrell, S Amadesi, EF Grady, NW Bunnett
Journal of Biological Chemistry 279 (14), 13532-13539, 2004
2072004
Protease-activated receptor 2: activation, signalling and function
GS Cottrell, S Amadesi, F Schmidlin, N Bunnett
Biochemical Society Transactions 31 (6), 1191-1197, 2003
1712003
Pseudomonas aeruginosa elastase disables proteinase-activated receptor 2 in respiratory epithelial cells
S Dulon, D Leduc, GS Cottrell, J D'Alayer, KK Hansen, NW Bunnett, ...
American journal of respiratory cell and molecular biology 32 (5), 411-419, 2005
1612005
c-Cbl mediates ubiquitination, degradation, and down-regulation of human protease-activated receptor 2
C Jacob, GS Cottrell, D Gehringer, F Schmidlin, EF Grady, NW Bunnett
Journal of Biological Chemistry 280 (16), 16076-16087, 2005
1582005
Localization of calcitonin receptor‐like receptor and receptor activity modifying protein 1 in enteric neurons, dorsal root ganglia, and the spinal cord of the rat
GS Cottrell, D Roosterman, JC Marvizon, B Song, E Wick, S Pikios, ...
Journal of Comparative Neurology 490 (3), 239-255, 2005
1232005
Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia
W Knecht, GS Cottrell, S Amadesi, J Mohlin, A Skåregärde, K Gedda, ...
Journal of Biological Chemistry 282 (36), 26089-26100, 2007
1222007
Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury
D Gazzieri, M Trevisani, J Springer, S Harrison, GS Cottrell, E Andre, ...
Free Radical Biology and Medicine 43 (4), 581-589, 2007
1102007
Cloning, expression, and characterization of human cytosolic aminopeptidase P: a single manganese (II)-dependent enzyme
GS Cottrell, NM Hooper, AJ Turner
Biochemistry 39 (49), 15121-15128, 2000
1032000
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