Gurdyal Besra
Gurdyal Besra
Bardrick Professor of Microbial Physiology & Chemistry
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Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis
JT Belisle, VD Vissa, T Sievert, K Takayama, PJ Brennan, GS Besra
Science 276 (5317), 1420-1422, 1997
Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum
RF Waller, PJ Keeling, RGK Donald, B Striepen, E Handman, ...
Proceedings of the National Academy of Sciences 95 (21), 12352-12357, 1998
Pathway to Synthesis and Processing of Mycolic Acids in Mycobacterium tuberculosis
K Takayama, C Wang, GS Besra
Clinical microbiology reviews 18 (1), 81-101, 2005
CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor
NA Borg, KS Wun, L Kjer-Nielsen, MCJ Wilce, DG Pellicci, R Koh, ...
Nature 448 (7149), 44-49, 2007
Detection and molecular characterization of 9000-year-old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean
I Hershkovitz, HD Donoghue, DE Minnikin, GS Besra, OYC Lee, ...
PloS one 3 (10), e3426, 2008
The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.
AE Belanger, GS Besra, ME Ford, K Mikusová, JT Belisle, PJ Brennan, ...
Proceedings of the National Academy of Sciences 93 (21), 11919-11924, 1996
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response
V Briken, SA Porcelli, GS Besra, L Kremer
Molecular microbiology 53 (2), 391-403, 2004
CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection
DB Moody, T Ulrichs, W Mühlecker, DC Young, SS Gurcha, E Grant, ...
Nature 404 (6780), 884-888, 2000
A Novel Pathogenic Taxon of the Mycobacterium tuberculosis Complex, Canetti: Characterization of an Exceptional Isolate from Africa
D Van Soolingen, T Hoogenboezem, PEW De Haas, PWM Hermans, ...
International Journal of Systematic and Evolutionary Microbiology 47 (4 …, 1997
Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells
DB Moody, BB Reinhold, MR Guy, EM Beckman, DE Frederique, ...
Science 278 (5336), 283-286, 1997
Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum
NJ Garton, SJ Waddell, AL Sherratt, SM Lee, RJ Smith, C Senner, J Hinds, ...
PLoS medicine 5 (4), e75, 2008
IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production
JM Coquet, K Kyparissoudis, DG Pellicci, G Besra, SP Berzins, MJ Smyth, ...
The Journal of Immunology 178 (5), 2827-2834, 2007
The crystal structure of human CD1d with and without α-galactosylceramide
M Koch, VS Stronge, D Shepherd, SD Gadola, B Mathew, G Ritter, ...
Nature immunology 6 (8), 819-826, 2005
The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis
SM Newton, C Lau, SS Gurcha, GS Besra, CW Wright
Journal of ethnopharmacology 79 (1), 57-67, 2002
Apolipoprotein-mediated pathways of lipid antigen presentation
P Elzen, S Garg, L León, M Brigl, EA Leadbetter, JE Gumperz, ...
Nature 437 (7060), 906-910, 2005
Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of α-galactosylceramides
KOA Yu, JS Im, A Molano, Y Dutronc, PA Illarionov, C Forestier, ...
Proceedings of the National Academy of Sciences 102 (9), 3383-3388, 2005
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol
K Mikusova, RA Slayden, GS Besra, PJ Brennan
Antimicrobial agents and chemotherapy 39 (11), 2484-2489, 1995
Activation of the pro-drug ethionamide is regulated in mycobacteria
AR Baulard, JC Betts, J Engohang-Ndong, S Quan, RA McAdam, ...
Journal of Biological Chemistry 275 (36), 28326-28331, 2000
The complete genome sequence and analysis of Corynebacterium diphtheriae NCTC13129
AM Cerdeno‐Tarraga, A Efstratiou, LG Dover, MTG Holden, M Pallen, ...
Nucleic acids research 31 (22), 6516-6523, 2003
Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans
C De Santo, M Salio, SH Masri, LYH Lee, T Dong, AO Speak, S Porubsky, ...
The Journal of clinical investigation 118 (12), 4036-4048, 2008
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