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Chen Zhang
Chen Zhang
Baylor college of medicine, Temple University
Verified email at bcm.edu
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Year
Single-cell transcriptome analysis reveals dynamic cell populations and differential gene expression patterns in control and aneurysmal human aortic tissue
Y Li, P Ren, A Dawson, HG Vasquez, W Ageedi, C Zhang, W Luo, R Chen, ...
Circulation 142 (14), 1374-1388, 2020
1772020
Critical role of cytosolic DNA and its sensing adaptor STING in aortic degeneration, dissection, and rupture
W Luo, Y Wang, L Zhang, P Ren, C Zhang, Y Li, AR Azares, M Zhang, ...
Circulation 141 (1), 42-66, 2020
1562020
Effect of ciprofloxacin on susceptibility to aortic dissection and rupture in mice
SA LeMaire, L Zhang, W Luo, P Ren, AR Azares, Y Wang, C Zhang, ...
JAMA surgery 153 (9), e181804-e181804, 2018
992018
Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation
Z Dong, P Zhao, M Xu, C Zhang, W Guo, H Chen, J Tian, H Wei, R Lu, ...
Scientific reports 7 (1), 2691, 2017
922017
Targeting the nlrp 3 inflammasome with inhibitor mcc 950 prevents aortic aneurysms and dissections in mice
P Ren, D Wu, R Appel, L Zhang, C Zhang, W Luo, AAB Robertson, ...
Journal of the American Heart Association 9 (7), e014044, 2020
722020
Critical role of ADAMTS-4 in the development of sporadic aortic aneurysm and dissection in mice
P Ren, M Hughes, S Krishnamoorthy, S Zou, L Zhang, D Wu, C Zhang, ...
Scientific reports 7 (1), 12351, 2017
722017
Stachydrine protects against pressure overload-induced cardiac hypertrophy by suppressing autophagy
TT Cao, HH Chen, Z Dong, YW Xu, P Zhao, W Guo, HC Wei, C Zhang, ...
Cellular Physiology and Biochemistry 42 (1), 103-114, 2017
532017
Role of STIM1 (stromal interaction molecule 1) in hypertrophy-related contractile dysfunction
CD Troupes, M Wallner, G Borghetti, C Zhang, S Mohsin, D von Lewinski, ...
Circulation research 121 (2), 125-136, 2017
472017
Cardiomyocyte PKA ablation enhances basal contractility while eliminates cardiac β-adrenergic response without adverse effects on the heart
Y Zhang, WE Wang, X Zhang, Y Li, B Chen, C Liu, X Ai, X Zhang, Y Tian, ...
Circulation Research 124 (12), 1760-1777, 2019
442019
Programmed cell death in aortic aneurysm and dissection: a potential therapeutic target
A Chakraborty, Y Li, C Zhang, Y Li, SA LeMaire, YH Shen
Journal of molecular and cellular cardiology 163, 67-80, 2022
422022
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations
J Park, AM Lucas, X Zhang, K Chaudhary, JH Cho, G Nadkarni, A Dobbyn, ...
Nature medicine 27 (1), 66-72, 2021
412021
Single-cell analysis of aneurysmal aortic tissue in patients with Marfan syndrome reveals dysfunctional TGF-β signaling
A Dawson, Y Li, Y Li, P Ren, HG Vasquez, C Zhang, KR Rebello, ...
Genes 13 (1), 95, 2021
282021
Increasing T‐type calcium channel activity by β‐adrenergic stimulation contributes to β‐adrenergic regulation of heart rates
Y Li, X Zhang, C Zhang, X Zhang, Y Li, Z Qi, C Szeto, M Tang, Y Peng, ...
The Journal of Physiology 596 (7), 1137-1151, 2018
232018
Second heart field–derived cells contribute to angiotensin II–mediated ascending aortopathies
H Sawada, Y Katsumata, H Higashi, C Zhang, Y Li, S Morgan, LH Lee, ...
Circulation 145 (13), 987-1001, 2022
222022
Caveolae-localized L-type Ca2+ channels do not contribute to function or hypertrophic signalling in the mouse heart
RN Correll, CA Makarewich, H Zhang, C Zhang, MA Sargent, AJ York, ...
Cardiovascular research 113 (7), 749-759, 2017
222017
Preventing cholesterol-induced perk (protein kinase RNA-like endoplasmic reticulum kinase) signaling in smooth muscle cells blocks atherosclerotic plaque formation
A Chattopadhyay, P Guan, S Majumder, K Kaw, Z Zhou, C Zhang, ...
Arteriosclerosis, thrombosis, and vascular biology 42 (8), 1005-1022, 2022
152022
Epigenetic induction of smooth muscle cell phenotypic alterations in aortic aneurysms and dissections
A Chakraborty, Y Li, C Zhang, Y Li, KR Rebello, S Li, S Xu, HG Vasquez, ...
Circulation 148 (12), 959-977, 2023
142023
Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model
A Toib, C Zhang, G Borghetti, X Zhang, M Wallner, Y Yang, CD Troupes, ...
American Journal of Physiology-Heart and Circulatory Physiology 313 (3 …, 2017
112017
Smooth muscle α-actin missense variant promotes atherosclerosis through modulation of intracellular cholesterol in smooth muscle cells
K Kaw, A Chattopadhyay, P Guan, J Chen, S Majumder, X Duan, S Ma, ...
European Heart Journal 44 (29), 2713-2726, 2023
92023
Aortic stress activates an adaptive program in thoracic aortic smooth muscle cells that maintains aortic strength and protects against aneurysm and dissection in mice
C Zhang, Y Li, A Chakraborty, Y Li, KR Rebello, P Ren, W Luo, L Zhang, ...
Arteriosclerosis, thrombosis, and vascular biology 43 (2), 234-252, 2023
92023
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