| Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action JA Dunkle, L Xiong, AS Mankin, JHD Cate Proceedings of the national academy of sciences 107 (40), 17152-17157, 2010 | 490 | 2010 |
| Structures of the bacterial ribosome in classical and hybrid states of tRNA binding JA Dunkle, L Wang, MB Feldman, A Pulk, VB Chen, GJ Kapral, J Noeske, ... Science 332 (6032), 981-984, 2011 | 423 | 2011 |
| Structures of the ribosome in intermediate states of ratcheting W Zhang, JA Dunkle, JHD Cate Science 325 (5943), 1014-1017, 2009 | 299 | 2009 |
| The mechanisms of RNA SHAPE chemistry JL McGinnis, JA Dunkle, JHD Cate, KM Weeks Journal of the American Chemical Society 134 (15), 6617-6624, 2012 | 207 | 2012 |
| Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis B Llano-Sotelo, J Dunkle, D Klepacki, W Zhang, P Fernandes, JHD Cate, ... Antimicrobial agents and chemotherapy 54 (12), 4961-4970, 2010 | 170 | 2010 |
| Ribosome structure and dynamics during translocation and termination JA Dunkle, JHD Cate Annual review of biophysics 39 (1), 227-244, 2010 | 116 | 2010 |
| Structural insights into+ 1 frameshifting promoted by expanded or modification-deficient anticodon stem loops T Maehigashi, JA Dunkle, SJ Miles, CM Dunham Proceedings of the National Academy of Sciences 111 (35), 12740-12745, 2014 | 71 | 2014 |
| Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA JA Dunkle, K Vinal, PM Desai, N Zelinskaya, M Savic, DM West, GL Conn, ... Proceedings of the National Academy of Sciences 111 (17), 6275-6280, 2014 | 62 | 2014 |
| Mechanism of tRNA-mediated+ 1 ribosomal frameshifting S Hong, S Sunita, T Maehigashi, ED Hoffer, JA Dunkle, CM Dunham Proceedings of the National Academy of Sciences 115 (44), 11226-11231, 2018 | 51 | 2018 |
| Molecular determinants for CRISPR RNA maturation in the Cas10–Csm complex and roles for non-Cas nucleases FC Walker, L Chou-Zheng, JA Dunkle, A Hatoum-Aslan Nucleic acids research 45 (4), 2112-2123, 2017 | 51 | 2017 |
| Regulation of cyclic oligoadenylate synthesis by the Staphylococcus epidermidis Cas10-Csm complex M Nasef, MC Muffly, AB Beckman, SJ Rowe, FC Walker, A Hatoum-Aslan, ... Rna 25 (8), 948-962, 2019 | 43 | 2019 |
| Defining the mRNA recognition signature of a bacterial toxin protein MA Schureck, JA Dunkle, T Maehigashi, SJ Miles, CM Dunham Proceedings of the National Academy of Sciences 112 (45), 13862-13867, 2015 | 37 | 2015 |
| Reorganization of an intersubunit bridge induced by disparate 16S ribosomal ambiguity mutations mimics an EF-Tu-bound state CE Fagan, JA Dunkle, T Maehigashi, MN Dang, A Devaraj, SJ Miles, ... Proceedings of the National Academy of Sciences 110 (24), 9716-9721, 2013 | 34 | 2013 |
| Direct observation of intermediates in the SufS cysteine desulfurase reaction reveals functional roles of conserved active-site residues M Blahut, CE Wise, MR Bruno, G Dong, TM Makris, PA Frantom, ... Journal of Biological Chemistry 294 (33), 12444-12458, 2019 | 29 | 2019 |
| Structural insights into translational recoding by frameshift suppressor tRNASufJ CE Fagan, T Maehigashi, JA Dunkle, SJ Miles, CM Dunham RNA 20 (12), 1944-1954, 2014 | 29 | 2014 |
| Structural evidence for dimer-interface-driven regulation of the type II cysteine desulfurase, SufS JA Dunkle, MR Bruno, FW Outten, PA Frantom Biochemistry 58 (6), 687-696, 2018 | 28 | 2018 |
| Mechanisms of mRNA frame maintenance and its subversion during translation of the genetic code JA Dunkle, CM Dunham Biochimie 114, 90-96, 2015 | 28 | 2015 |
| Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases JA Dunkle, MR Bruno, PA Frantom Acta Crystallographica Section D: Structural Biology 76 (3), 291-301, 2020 | 12 | 2020 |
| Shared requirements for key residues in the antibiotic resistance enzymes ErmC and ErmE suggest a common mode of RNA recognition SJ Rowe, RJ Mecaskey, M Nasef, RC Talton, RE Sharkey, JC Halliday, ... Journal of Biological Chemistry 295 (51), 17476-17485, 2020 | 8 | 2020 |
| The β-latch structural element of the SufS cysteine desulfurase mediates active site accessibility and SufE transpersulfurase positioning RK Gogar, F Carroll, JV Conte, M Nasef, JA Dunkle, PA Frantom Journal of Biological Chemistry 299 (3), 2023 | 7 | 2023 |
Tatsuya MaehigashiJohnson & JohnsonGeverifieerd e-mailadres voor its.jnj.com
