Brennan Decker
Brennan Decker
Foundation Medicine
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Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease
EA Worthey, AN Mayer, GD Syverson, D Helbling, BB Bonacci, B Decker, ...
Genetics in Medicine 13 (3), 255-262, 2011
Variation of BMP3 Contributes to Dog Breed Skull Diversity
JJ Schoenebeck, SA Hutchinson, A Byers, HC Beale, B Carrington, ...
PLoS genetics 8 (8), e1002849, 2012
Prediction of DNA repair inhibitor response in short-term patient-derived ovarian cancer organoids
SJ Hill, B Decker, EA Roberts, NS Horowitz, MG Muto, MJ Worley, ...
Cancer discovery 8 (11), 1404-1421, 2018
Cancer risks associated with germline PALB2 pathogenic variants: an international study of 524 families
X Yang, G Leslie, A Doroszuk, S Schneider, J Allen, B Decker, ...
Journal of Clinical Oncology 38 (7), 674, 2020
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing
DF Easton, F Lesueur, B Decker, K Michailidou, J Li, J Allen, C Luccarini, ...
Journal of medical genetics 53 (5), 298-309, 2016
Whole genome sequencing of canids reveals genomic regions under selection and variants influencing morphology
J Plassais, J Kim, BW Davis, DM Karyadi, AN Hogan, AC Harris, B Decker, ...
Nature communications 10 (1), 1-14, 2019
Homologous mutation to human BRAF V600E is common in naturally occurring canine bladder cancer—Evidence for a relevant model system and urine-based diagnostic test
B Decker, HG Parker, D Dhawan, EM Kwon, E Karlins, BW Davis, ...
Molecular Cancer Research 13 (6), 993-1002, 2015
Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens
GM Lynn, C Sedlik, F Baharom, Y Zhu, RA Ramirez-Valdez, VL Coble, ...
Nature biotechnology 38 (3), 320-332, 2020
A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit
DM Karyadi, E Karlins, B Decker, BM vonHoldt, G Carpintero-Ramirez, ...
PLoS genetics 9 (3), e1003409, 2013
Rare, protein-truncating variants in ATM, CHEK2 and PALB2, but not XRCC2, are associated with increased breast cancer risks
B Decker, J Allen, C Luccarini, KA Pooley, M Shah, MK Bolla, Q Wang, ...
Journal of medical genetics 54 (11), 732-741, 2017
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor
B Decker, BW Davis, M Rimbault, AH Long, E Karlins, V Jagannathan, ...
Genome research 25 (11), 1646-1655, 2015
Breast Cancer Risk Genes-Association Analysis in More than 113,000 Women.
L Dorling, S Carvalho, J Allen, A González-Neira, C Luccarini, ...
N Engl J Med, 428-439, 2021
Biallelic BRCA2 Mutations Shape the Somatic Mutational Landscape of Aggressive Prostate Tumors
B Decker, DM Karyadi, BW Davis, E Karlins, LS Tillmans, JL Stanford, ...
The American Journal of Human Genetics 98 (5), 818-829, 2016
Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia
WX Wen, J Allen, KN Lai, S Mariapun, SN Hasan, PS Ng, DSC Lee, ...
Journal of medical genetics 55 (2), 97-103, 2018
Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
J Li, WX Wen, M Eklund, A Kvist, M Eriksson, HN Christensen, ...
International journal of cancer 144 (5), 1195-1204, 2019
Dysregulation of the homeobox transcription factor gene HOXB13: role in prostate cancer
B Decker, EA Ostrander
Pharmacogenomics and personalized medicine 7, 193, 2014
Periodically arranged interactions within the myosin filament backbone revealed by mechanical unzipping
B Decker, MSZ Kellermayer
Journal of molecular biology 377 (2), 307-310, 2008
Differential burden of rare and common variants on tumor characteristics, survival, and mode of detection in breast cancer
J Li, E Ugalde-Morales, WX Wen, B Decker, M Eriksson, A Torstensson, ...
Cancer research 78 (21), 6329-6338, 2018
Whole exome sequencing in 75 high-risk families with validation and replication in independent case-control studies identifies TANGO2, OR5H14, and CHAD as new prostate cancer …
DM Karyadi, MS Geybels, E Karlins, B Decker, L McIntosh, A Hutchinson, ...
Oncotarget 8 (1), 1495, 2017
Targeted Resequencing of the Coding Sequence of 38 Genes Near Breast Cancer GWAS Loci in a Large Case–Control Study
B Decker, J Allen, C Luccarini, KA Pooley, M Shah, MK Bolla, Q Wang, ...
Cancer Epidemiology and Prevention Biomarkers 28 (4), 822-825, 2019
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